Page last updated: 2024-09-04

moxifloxacin and clotrimazole

moxifloxacin has been researched along with clotrimazole in 6 studies

Compound Research Comparison

Studies
(moxifloxacin)
Trials
(moxifloxacin)
Recent Studies (post-2010)
(moxifloxacin)
Studies
(clotrimazole)
Trials
(clotrimazole)
Recent Studies (post-2010) (clotrimazole)
3,1575521,6902,005299503

Protein Interaction Comparison

ProteinTaxonomymoxifloxacin (IC50)clotrimazole (IC50)
Intermediate conductance calcium-activated potassium channel protein 4Homo sapiens (human)0.1667
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.59
Transient receptor potential cation channel subfamily M member 2Homo sapiens (human)3
Bile salt export pumpHomo sapiens (human)10
Glucocorticoid receptorHomo sapiens (human)3.258
ATP-dependent translocase ABCB1Mus musculus (house mouse)3.5
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)3.258
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)7.936
ATP-dependent translocase ABCB1Homo sapiens (human)4.9
Cytochrome P450 3A4Homo sapiens (human)0.0406
Adenosine receptor A3Homo sapiens (human)4.752
Muscarinic acetylcholine receptor M1Homo sapiens (human)6.869
AromataseHomo sapiens (human)0.0018
Cytochrome P450 2C9 Homo sapiens (human)0.016
Beta-3 adrenergic receptorHomo sapiens (human)7.208
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)4.752
Alpha-2B adrenergic receptorHomo sapiens (human)8.159
Potassium-transporting ATPase subunit betaSus scrofa (pig)5.2
Potassium-transporting ATPase alpha chain 1Sus scrofa (pig)5.2
Muscarinic acetylcholine receptor M3Homo sapiens (human)9.928
Glycine receptor subunit betaRattus norvegicus (Norway rat)3.258
ATP-dependent translocase ABCB1Mus musculus (house mouse)4.8
D(1A) dopamine receptorHomo sapiens (human)9.017
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)6
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.59
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)3.258
Sodium-dependent noradrenaline transporter Homo sapiens (human)7.936
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)3.258
Thromboxane-A synthase Homo sapiens (human)0.014
Histamine H2 receptorHomo sapiens (human)5.165
C-X-C chemokine receptor type 1Homo sapiens (human)5.9677
Vasopressin V2 receptorHomo sapiens (human)2.6059
Sodium-dependent serotonin transporterHomo sapiens (human)5.76
Cytochrome P450 2C19Homo sapiens (human)0.016
Mu-type opioid receptorHomo sapiens (human)1.802
D(3) dopamine receptorHomo sapiens (human)2.647
Delta-type opioid receptorHomo sapiens (human)4.978
Kappa-type opioid receptorHomo sapiens (human)6.303
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)4.752
C-C chemokine receptor type 4Homo sapiens (human)1.6
Transitional endoplasmic reticulum ATPaseHomo sapiens (human)1.4
Sodium-dependent dopamine transporter Homo sapiens (human)5.581
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.0199
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.59
Nuclear receptor subfamily 1 group I member 3 Homo sapiens (human)0.29
Lanosterol 14-alpha demethylaseHomo sapiens (human)0.13
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)5.9
Bile acid receptorHomo sapiens (human)3.24

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sen, S; Sinha, N1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gao, Y; Ji, Y; Lin, Y; Lin, Z; Lu, Y; Yang, Y; Zhang, L1

Reviews

1 review(s) available for moxifloxacin and clotrimazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

5 other study(ies) available for moxifloxacin and clotrimazole

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Antibiotics and antimycotics in waste water treatment plants: Concentrations, removal efficiency, spatial and temporal variations, prediction, and ecological risk assessment.
    Environmental research, 2022, Volume: 215, Issue:Pt 1

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Clotrimazole; Environmental Monitoring; Moxifloxacin; Norfloxacin; Ofloxacin; Pefloxacin; Risk Assessment; Sewage; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Purification

2022