Page last updated: 2024-09-04

moxifloxacin and aprepitant

moxifloxacin has been researched along with aprepitant in 4 studies

Compound Research Comparison

Studies (moxifloxacin)	Trials (moxifloxacin)	Recent Studies (post-2010) (moxifloxacin)	Studies (aprepitant)	Trials (aprepitant)	Recent Studies (post-2010) (aprepitant)
3,157	552	1,690	769	229	521

Protein Interaction Comparison

Protein	Taxonomy	aprepitant (IC50)
Cytochrome P450 3A4	Homo sapiens (human)	0.046
Substance-P receptor	Homo sapiens (human)	0.0002
Substance-P receptor	Meriones unguiculatus (Mongolian gerbil)	0.0001

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (75.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Constanzer, ML; Dru, J; Evans, JK; Han, TH; Jin, B; Marbury, TC; Murphy, MG; Panebianco, D; Shadle, CR; Sun, H	1

Reviews

1 review(s) available for moxifloxacin and aprepitant

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for moxifloxacin and aprepitant

Article	Year
Lack of effect of aprepitant or its prodrug fosaprepitant on QTc intervals in healthy subjects. Anesthesia and analgesia, 2009, Volume: 109, Issue:2 Topics: Adolescent; Adult; Anti-Infective Agents; Antidepressive Agents; Aprepitant; Aza Compounds; Cross-Over Studies; Double-Blind Method; Electrocardiography; Electrocardiography, Ambulatory; Female; Fluoroquinolones; Heart Rate; Humans; Linear Models; Male; Middle Aged; Morpholines; Moxifloxacin; Prodrugs; Quinolines; Young Adult	2009

Article

Year

Lack of effect of aprepitant or its prodrug fosaprepitant on QTc intervals in healthy subjects.

Anesthesia and analgesia, 2009, Volume: 109, Issue:2

Topics: Adolescent; Adult; Anti-Infective Agents; Antidepressive Agents; Aprepitant; Aza Compounds; Cross-Over Studies; Double-Blind Method; Electrocardiography; Electrocardiography, Ambulatory; Female; Fluoroquinolones; Heart Rate; Humans; Linear Models; Male; Middle Aged; Morpholines; Moxifloxacin; Prodrugs; Quinolines; Young Adult

2009

Other Studies

2 other study(ies) available for moxifloxacin and aprepitant

Article	Year
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008