motilin and 4-diphenylacetoxy-1-1-dimethylpiperidinium

motilin has been researched along with 4-diphenylacetoxy-1-1-dimethylpiperidinium* in 1 studies

Other Studies

1 other study(ies) available for motilin and 4-diphenylacetoxy-1-1-dimethylpiperidinium

Article	Year
Muscarinic control of phase III contractions and motilin release in dogs. Peptides, 1997, Volume: 18, Issue:5 The role of muscarinic receptor subtype(s) in the control of gastric phase III contractions and motilin release was determined in dogs. Pirenzepine (226 nmol/kg/h) shortened the phase III cycle, causing an early increase in plasma motilin concentrations. Both AF-DX116BS and 4-DAMP inhibited the occurrence of spontaneous and motilin-induced phase III contractions, and 4-DAMP also inhibited the spontaneous increase in plasma motilin concentration. Only 4-DAMP inhibited carbachol-induced motilin release in perifused duodenal mucosal cells. In conclusion, M1 receptors are involved in the indirect inhibition of motilin release. Motilin-induced contractions are mediated mainly by M3 receptors and partly by M2 receptors, and M3 receptors are present in motilin-producing cells. Topics: Animals; Cell Separation; Dogs; Duodenum; Female; Infusions, Intravenous; Intestinal Mucosa; Male; Motilin; Muscarinic Antagonists; Piperidines; Pirenzepine; Stomach	1997

Article

Year

Muscarinic control of phase III contractions and motilin release in dogs.

Peptides, 1997, Volume: 18, Issue:5

The role of muscarinic receptor subtype(s) in the control of gastric phase III contractions and motilin release was determined in dogs. Pirenzepine (226 nmol/kg/h) shortened the phase III cycle, causing an early increase in plasma motilin concentrations. Both AF-DX116BS and 4-DAMP inhibited the occurrence of spontaneous and motilin-induced phase III contractions, and 4-DAMP also inhibited the spontaneous increase in plasma motilin concentration. Only 4-DAMP inhibited carbachol-induced motilin release in perifused duodenal mucosal cells. In conclusion, M1 receptors are involved in the indirect inhibition of motilin release. Motilin-induced contractions are mediated mainly by M3 receptors and partly by M2 receptors, and M3 receptors are present in motilin-producing cells.

Topics: Animals; Cell Separation; Dogs; Duodenum; Female; Infusions, Intravenous; Intestinal Mucosa; Male; Motilin; Muscarinic Antagonists; Piperidines; Pirenzepine; Stomach

1997