morpholine has been researched along with thienopyrimidine in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hollander, I; Toral-Barza, L; Verheijen, JC; Yu, K; Zask, A | 1 |
| Brooijmans, N; Hollander, I; Kaplan, J; Toral-Barza, L; Verheijen, JC; Yu, K; Zask, A | 1 |
2 other study(ies) available for morpholine and thienopyrimidine
| Article | Year |
|---|---|
Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K.
Topics: Cell Line, Tumor; Drug Discovery; Humans; Intracellular Signaling Peptides and Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Structure-Activity Relationship; TOR Serine-Threonine Kinases; Tropanes | 2010 |
Discovery of 3,6-dihydro-2H-pyran as a morpholine replacement in 6-aryl-1H-pyrazolo[3,4-d]pyrimidines and 2-arylthieno[3,2-d]pyrimidines: ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR).
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Computer Simulation; Drug Discovery; Intracellular Signaling Peptides and Proteins; Mice; Microsomes; Models, Molecular; Morpholines; Protein Serine-Threonine Kinases; Pyrans; Pyrazoles; Pyridines; Pyrimidines; TOR Serine-Threonine Kinases | 2010 |