morphinans has been researched along with protoberberine* in 2 studies
2 other study(ies) available for morphinans and protoberberine
| Article | Year |
|---|---|
Over 100 Million Years of Enzyme Evolution Underpinning the Production of Morphine in the Papaveraceae Family of Flowering Plants.
Phylogenomic analysis of whole genome sequences of five benzylisoquinoline alkaloid (BIA)-producing species from the Ranunculales and Proteales orders of flowering plants revealed the sequence and timing of evolutionary events leading to the diversification of these compounds. ( Topics: Benzophenanthridines; Benzylisoquinolines; Berberine Alkaloids; Enzymes; Evolution, Molecular; Gene Duplication; Isoquinolines; Morphinans; Morphine; Multigene Family; Noscapine; Papaveraceae; Phylogeny; Plant Proteins | 2020 |
New bisbenzylisoquinolines, fatty acid amidic aporphines, and a protoberberine from Formosan Cocculus orbiculatus.
Two new bisbenzylisoquinoline alkaloids, (+)-coccuorbiculatine A (2) and (+)-10-hydroxyisotrilobine (3), two new amidic aporphines, a mixture of (+)-laurelliptinhexadecan-1-one (6) and (+)-laurelliptinoctadecan-1-one (7), and one new protoberberine (-)-4-methoxy-13,14-dihydrooxypalmatine (8) have been isolated from the stems of Taiwanese Cocculus orbiculatus. The structures were established on the basis of extensive analysis of spectroscopic data and by comparison with known related metabolites. Cytotoxicity of the isolated compounds was examined toward HepG2, Hep3B, MCF-7, and MDA-MB-231 cancer cell lines. Alkaloids 1 and (-)-sinococuline (9) showed significant inhibitory activity against the target cell lines. Topics: Antineoplastic Agents, Phytogenic; Aporphines; Benzylisoquinolines; Berberine Alkaloids; Fatty Acids; Menispermum; Molecular Structure; Morphinans; Plant Stems; Plants, Medicinal; Taiwan | 2005 |