morphinans and oxymorphindole

morphinans has been researched along with oxymorphindole* in 2 studies

Other Studies

2 other study(ies) available for morphinans and oxymorphindole

Article	Year
Agonist and antagonist activities of ligands derived from naltrexone and oxymorphone. Life sciences, 1992, Volume: 50, Issue:20 The pharmacological profile of naltrindole (NTI) and three of its analogues, N-methyl-NTI (N-Me-NTI), oxymorphindole (OMI) and naltriben (NTB) were studied in antinociceptive assays. The compounds were found to have agonist activities that appear to be mediated mainly by kappa opioid receptors because norbinaltorphimine (nor-BNI), the selective kappa opioid receptor antagonist inhibited their effects significantly. All of the compounds, behaved as antagonists at doses that were lower than those that produced agonist effects and they possessed a profile that was very selective for inhibiting the antinociceptive activities of delta opioid receptor agonists. Differential antagonism by NTB of the activities of DSLET and DPDPE was demonstrated. Topics: Animals; Indoles; Ligands; Male; Mice; Morphinans; Morpholines; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa	1992
Opioid modulation of immunoglobulin production by lymphocytes isolated from Peyer's patches and spleen. Annals of the New York Academy of Sciences, 1992, Apr-15, Volume: 650 Topics: Animals; Antibody Formation; Cells, Cultured; Concanavalin A; In Vitro Techniques; Indoles; Lipopolysaccharides; Lymphocytes; Morphinans; Morpholines; Naltrexone; Peyer's Patches; Spleen	1992

Article

Year

Agonist and antagonist activities of ligands derived from naltrexone and oxymorphone.

Life sciences, 1992, Volume: 50, Issue:20

The pharmacological profile of naltrindole (NTI) and three of its analogues, N-methyl-NTI (N-Me-NTI), oxymorphindole (OMI) and naltriben (NTB) were studied in antinociceptive assays. The compounds were found to have agonist activities that appear to be mediated mainly by kappa opioid receptors because norbinaltorphimine (nor-BNI), the selective kappa opioid receptor antagonist inhibited their effects significantly. All of the compounds, behaved as antagonists at doses that were lower than those that produced agonist effects and they possessed a profile that was very selective for inhibiting the antinociceptive activities of delta opioid receptor agonists. Differential antagonism by NTB of the activities of DSLET and DPDPE was demonstrated.

Topics: Animals; Indoles; Ligands; Male; Mice; Morphinans; Morpholines; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa

1992

Opioid modulation of immunoglobulin production by lymphocytes isolated from Peyer's patches and spleen.

Annals of the New York Academy of Sciences, 1992, Apr-15, Volume: 650

Topics: Animals; Antibody Formation; Cells, Cultured; Concanavalin A; In Vitro Techniques; Indoles; Lipopolysaccharides; Lymphocytes; Morphinans; Morpholines; Naltrexone; Peyer's Patches; Spleen

1992