morphinans has been researched along with hydroxide-ion* in 1 studies
1 other study(ies) available for morphinans and hydroxide-ion
Article | Year |
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A convenient synthesis of delta(7,8)-morphinan-6-one and its direct oxidation to 14-hydroxy-delta(7,8)-morphinan-6-one.
Synthesis of Delta(7,8)-morphinan-6-one by Grewe cyclization and bromoketalization reaction as crucial steps is described. Introduction of a hydroxyl group at 14-position is demonstrated by direct oxidation with MnO(2) in the presence of silica gel. Topics: Cyclization; Hydrogenation; Hydromorphone; Hydroxides; Ketones; Manganese Compounds; Morphinans; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxides; Silicon Dioxide; Stereoisomerism | 2002 |