Page last updated: 2024-09-03

morphiceptin and naltrexone

morphiceptin has been researched along with naltrexone in 7 studies

Compound Research Comparison

Studies
(morphiceptin)
Trials
(morphiceptin)
Recent Studies (post-2010)
(morphiceptin)
Studies
(naltrexone)
Trials
(naltrexone)
Recent Studies (post-2010) (naltrexone)
1390128,7451,2282,642

Protein Interaction Comparison

ProteinTaxonomymorphiceptin (IC50)naltrexone (IC50)
Cytochrome P450 2D6Homo sapiens (human)1
Delta-type opioid receptorMus musculus (house mouse)0.0051
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0063
Kappa-type opioid receptorMus musculus (house mouse)0.006
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0005
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0005
Mu-type opioid receptorHomo sapiens (human)0.006
Delta-type opioid receptorHomo sapiens (human)0.0319
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.0093
Kappa-type opioid receptorHomo sapiens (human)0.0377
Mu-type opioid receptorMus musculus (house mouse)0.0076
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0004

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Portoghese, PS; Takemori, AE1
Haddad, GG; Jeng, HJ; Lai, TL1
Billington, CJ; Gosnell, BA; Levine, AS; Morley, JE1
Goodman, M; Malmberg, AB; Ro, S; Schiller, P; Yaksh, TL1
Kübler, W; Mura, RA; Niroomand, F; Piacentini, L1
Bates, SL; Davison, JS; Lang, ME; Meddings, JB1
Dong, S; Li, M; Ma, G; Zhou, L1

Other Studies

7 other study(ies) available for morphiceptin and naltrexone

ArticleYear
Receptors for opioid peptides in the guinea-pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: Alkylation; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens

1985
Effect of endorphins on heart rate and blood pressure in adult dogs.
    The American journal of physiology, 1986, Volume: 250, Issue:5 Pt 2

    Topics: Animals; Atropine; Blood Pressure; Consciousness; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Heart; Heart Rate; Naloxone; Naltrexone

1986
Which opioid receptor mechanism modulates feeding?
    Appetite, 1984, Volume: 5, Issue:1

    Topics: Animals; Azocines; Diprenorphine; Dynorphins; Endorphins; Feeding Behavior; Humans; Mice; Naloxone; Naltrexone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma

1984
Characterization of the spinal antinociceptive activity of constrained peptidomimetic opioids.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: Amino Acid Sequence; Analgesia; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Injections, Spinal; Male; Mice; Molecular Sequence Data; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Oligopeptides; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Structure-Activity Relationship; Vas Deferens

1995
Opioid receptor agonists activate pertussis toxin-sensitive G proteins and inhibit adenylyl cyclase in canine cardiac sarcolemma.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:5

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Analgesics; Analysis of Variance; Animals; Diprenorphine; Dogs; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP Phosphohydrolases; GTP-Binding Proteins; Myocardium; Naltrexone; Narcotic Antagonists; Pertussis Toxin; Sarcolemma; Virulence Factors, Bordetella

1996
Opioid receptors on guinea-pig intestinal crypt epithelial cells.
    The Journal of physiology, 1996, Nov-15, Volume: 497 ( Pt 1)

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding, Competitive; Cells, Cultured; Cyclic AMP; Endorphins; Enkephalins; Flow Cytometry; Guinea Pigs; Immunohistochemistry; Intestinal Absorption; Intestinal Mucosa; Intestines; Levorphanol; Male; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Stereoisomerism; Vasoactive Intestinal Peptide

1996
Analgesic properties of chimeric peptide based on morphiceptin and PFRTic-amide.
    Regulatory peptides, 2012, Nov-10, Volume: 179, Issue:1-3

    Topics: Analgesia; Analgesics, Opioid; Animals; Arginine; Dose-Response Relationship, Drug; Endorphins; Guinea Pigs; Male; Mice; Morphinans; Naloxone; Naltrexone; Neuropeptides; Opioid Peptides; Proline; Receptors, Neuropeptide; Tetrahydroisoquinolines; Time Factors

2012