Page last updated: 2024-09-03

morphiceptin and morphine

morphiceptin has been researched along with morphine in 21 studies

Compound Research Comparison

Studies
(morphiceptin)
Trials
(morphiceptin)
Recent Studies (post-2010)
(morphiceptin)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
13901244,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomymorphiceptin (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199013 (61.90)18.7374
1990's8 (38.10)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boon, F; Cain, DP; Corcoran, ME1
Basbaum, AI; Levine, JD; Perry, F; Taiwo, YO1
Levine, JD; Taiwo, YO1
Geppert, M; Illes, P; Jackisch, R1
Bero, LA; Kuhn, CM; Lurie, SN1
Nilekani, SP; Nuchols, PA; Oeltgen, PR; Spurrier, WA; Su, TP1
Snead, OC1
Chang, KJ1
Root-Bernstein, RS1
Clouet, DH; Yonehara, N1
Bostock, E; Chang, KJ; Dingledine, R; Xu, G1
Han, JS; Xie, CW1
Barchas, JD; Madden, J; Mauk, MD; Thompson, RF1
Chang, JK; Chang, KJ; Killian, A; Wei, ET1
Bakogeorgou, E; Castanas, E; Hatzoglou, A; Ouafik, L; Thermos, K1
Donahoe, RM; Ketelsen, D; Madden, JJ; Oleson, D; Whaley, WL1
Aoki, Y; Katao, Y; Katsumata, S; Minami, M; Nakagawa, T; Onogi, T; Satoh, M1
de Andrés, I; Reinoso-Barbero, F1
Banks, WA; Harrison, LM; Kastin, AJ; Zadina, JE1
Ammer, H; Schulz, R1
Rabkin, SW1

Other Studies

21 other study(ies) available for morphiceptin and morphine

ArticleYear
Involvement of multiple opiate receptors in opioid kindling.
    Brain research, 1990, May-28, Volume: 517, Issue:1-2

    Topics: Animals; beta-Endorphin; Convulsants; Endorphins; Enkephalin, Leucine; Kindling, Neurologic; Male; Morphine; Oligopeptides; Rats; Receptors, Opioid

1990
Paradoxical analgesia produced by low doses of the opiate-antagonist naloxone is mediated by interaction at a site with characteristics of the delta opioid receptor.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:1

    Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Male; Morphine; Naloxone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta

1989
Involvement of the mu-opiate receptor in peripheral analgesia.
    Neuroscience, 1989, Volume: 32, Issue:3

    Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Morphine; Peripheral Nerves; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1989
Characterization of opioid receptors modulating noradrenaline release in the hippocampus of the rabbit.
    Journal of neurochemistry, 1986, Volume: 46, Issue:6

    Topics: Animals; Benzomorphans; Clonidine; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Hippocampus; Morphine; Norepinephrine; Rabbits; Receptors, Opioid

1986
Early ontogeny of kappa-opioid receptor regulation of prolactin secretion in the rat.
    Brain research, 1987, Dec-15, Volume: 465, Issue:1-2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hydrazines; Morphine; Peptide Fragments; Prolactin; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin

1987
Further studies on opioids and hibernation: delta opioid receptor ligand selectively induced hibernation in summer-active ground squirrels.
    Life sciences, 1988, Volume: 43, Issue:19

    Topics: Analgesics; Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; Hibernation; Male; Morphine; Peptides; Proteins; Receptors, Opioid; Receptors, Opioid, delta; Reference Values; Sciuridae; Seasons; Structure-Activity Relationship

1988
Opiate-induced seizures: a study of mu and delta specific mechanisms.
    Experimental neurology, 1986, Volume: 93, Issue:2

    Topics: Animals; Electroencephalography; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Morphine; Narcotics; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures

1986
Structure-activity relationship and pharmacology of the highly selective mu-opioid agonist, morphiceptin.
    NIDA research monograph, 1986, Volume: 69

    Topics: Analgesia; Animals; Drug Tolerance; Endorphins; Morphine; Muscle, Smooth; Receptors, Opioid; Receptors, Opioid, mu; Structure-Activity Relationship

1986
Catecholamines bind to enkephalins, morphiceptin, and morphine.
    Brain research bulletin, 1987, Volume: 18, Issue:4

    Topics: Catecholamines; Dopamine; Endorphins; Enkephalins; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Morphine; Norepinephrine; Peptide Fragments

1987
Effects of delta and mu opiopeptides on the turnover and release of dopamine in rat striatum.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:1

    Topics: Animals; Corpus Striatum; Dopamine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Male; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1984
Mu opioid receptors participate in the excitatory effect of opiates in the hippocampal slice.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:3

    Topics: Action Potentials; Animals; Endorphins; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1984
Dynorphin: potent analgesic effect in spinal cord of the rat.
    Scientia Sinica. Series B, Chemical, biological, agricultural, medical & earth sciences, 1984, Volume: 27, Issue:2

    Topics: Analgesia; Analgesics; Animals; Drug Tolerance; Dynorphins; Endorphins; Female; Injections, Intraventricular; Injections, Spinal; Morphine; Naloxone; Pain; Peptide Fragments; Rats; Sensory Thresholds; Spinal Cord

1984
Opiates and classical conditioning: selective abolition of conditioned responses by activation of opiate receptors within the central nervous system.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:23

    Topics: Avoidance Learning; Cerebral Ventricles; Conditioning, Classical; Endorphins; Injections, Intraventricular; Morphine; Periaqueductal Gray; Receptors, Opioid

1982
Potent morphiceptin analogs: structure activity relationships and morphine-like activities.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2

    Topics: Animals; Chemical Phenomena; Chemistry; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Evoked Potentials; Female; Growth Hormone-Releasing Hormone; Guinea Pigs; Hormones; Male; Mice; Mice, Inbred Strains; Morphine; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship

1983
Morphine cross-reacts with somatostatin receptor SSTR2 in the T47D human breast cancer cell line and decreases cell growth.
    Cancer research, 1995, Dec-01, Volume: 55, Issue:23

    Topics: Base Sequence; Breast Neoplasms; Cell Division; Endorphins; Female; Hormone Antagonists; Humans; Molecular Sequence Data; Morphine; Narcotics; Octreotide; Receptors, Somatostatin; RNA, Messenger; Somatostatin; Tumor Cells, Cultured

1995
Mitogenic activation of human T lymphocytes induces a high affinity morphine binding site.
    Advances in experimental medicine and biology, 1995, Volume: 373

    Topics: Analgesics; beta-Endorphin; Cells, Cultured; Culture Media; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Interleukin-2; Ligands; Lymphocyte Activation; Mitogens; Morphine; Naloxone; Phytohemagglutinins; Receptors, Opioid; T-Lymphocytes

1995
DAMGO, a mu-opioid receptor selective ligand, distinguishes between mu-and kappa-opioid receptors at a different region from that for the distinction between mu- and delta-opioid receptors.
    FEBS letters, 1995, May-01, Volume: 364, Issue:1

    Topics: Amino Acid Sequence; Analgesics; Animals; Cells, Cultured; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ligands; Molecular Sequence Data; Morphine; Naloxone; Oligopeptides; Opioid Peptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Fusion Proteins; Somatostatin; Structure-Activity Relationship

1995
Effects of opioid microinjections in the nucleus of the solitary tract on the sleep-wakefulness cycle states in cats.
    Anesthesiology, 1995, Volume: 82, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Cats; Drug Interactions; Electroencephalography; Endorphins; Microinjections; Morphine; Naloxone; Pyrrolidines; Receptors, Opioid; Sleep Stages; Sodium Chloride; Solitary Nucleus

1995
Effects of neonatal treatment with Tyr-MIF-1, morphiceptin, and morphine on development, tail flick, and blood-brain barrier transport.
    Brain research. Developmental brain research, 1993, Oct-15, Volume: 75, Issue:2

    Topics: Analgesics; Animals; Animals, Newborn; Behavior, Animal; Blood-Brain Barrier; Body Weight; Endorphins; Eye; Female; Growth; Iodine Radioisotopes; Morphine; MSH Release-Inhibiting Hormone; Nociceptors; Pain Measurement; Pregnancy; Rats

1993
Alterations in the expression of G-proteins and regulation of adenylate cyclase in human neuroblastoma SH-SY5Y cells chronically exposed to low-efficacy mu-opioids.
    The Biochemical journal, 1993, Oct-01, Volume: 295 ( Pt 1)

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Analgesics; Cell Differentiation; Cell Membrane; Cycloheximide; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GTP-Binding Proteins; Humans; Molecular Sequence Data; Morphine; Narcotics; Neuroblastoma; Time Factors; Tumor Cells, Cultured; Up-Regulation

1993
Morphine and morphiceptin increase the threshold for epinephrine-induced cardiac arrhythmias in the rat through brain mu opioid receptors.
    Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Brain; Endorphins; Epinephrine; Injections, Intravenous; Injections, Intraventricular; Male; Morphine; Rats; Rats, Wistar; Receptors, Opioid, mu

1993