Page last updated: 2024-09-03

morphiceptin and enkephalin, leucine-2-alanine

morphiceptin has been researched along with enkephalin, leucine-2-alanine in 19 studies

Compound Research Comparison

Studies
(morphiceptin)
Trials
(morphiceptin)
Recent Studies (post-2010)
(morphiceptin)
Studies
(enkephalin, leucine-2-alanine)
Trials
(enkephalin, leucine-2-alanine)
Recent Studies (post-2010) (enkephalin, leucine-2-alanine)
1390121,5812374

Protein Interaction Comparison

ProteinTaxonomymorphiceptin (IC50)enkephalin, leucine-2-alanine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.0915
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0017
Kappa-type opioid receptorMus musculus (house mouse)0.009
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0419
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)1.4691
Mu-type opioid receptorMus musculus (house mouse)0.009

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199016 (84.21)18.7374
1990's3 (15.79)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kondo, M; Matsumoto, H; Ohno, M; Sakamoto, H; Shimohigashi, Y; Takada, K; Yasunaga, T1
Dawson, G; Mangoura, D1
Herblin, WF; Kauer, JC; Tam, SW1
Geppert, M; Illes, P; Jackisch, R1
Kirby, GC; McQueen, DS1
Nilekani, SP; Nuchols, PA; Oeltgen, PR; Spurrier, WA; Su, TP1
Gottlieb, DI; Mattler, JA; Slaughter, MM1
Boudouresque, F; Bourhim, N; Cantau, P; Castanas, E; Giraud, P; Oliver, C2
Haddad, GG; Schaeffer, JI1
Portoghese, PS; Takemori, AE1
de Avila, A; Martinez, JL1
Snead, OC1
Haddad, GG; Jeng, HJ; Lai, TL1
Clouet, DH; Yonehara, N1
Bourhim, N; Cantau, P; Castanas, E; Giraud, P; Oliver, C1
Chang, JK; Chang, KJ; Cuatrecasas, P; Wei, ET1
Killian, A; Mack, KJ; Weyhenmeyer, JA1
Joshi, S; Lee, JW; Wong, YH1

Other Studies

19 other study(ies) available for morphiceptin and enkephalin, leucine-2-alanine

ArticleYear
Discriminative affinity labelling of opioid receptors by enkephalin and morphiceptin analogues containing 3-nitro-2-pyridinesulphenyl-activated thiol residues.
    Journal of chromatography, 1992, Apr-24, Volume: 597, Issue:1-2

    Topics: Affinity Labels; Amino Acid Sequence; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Indicators and Reagents; Molecular Sequence Data; Peptides; Pyridines; Radioligand Assay; Receptors, Opioid

1992
Chronic opioid treatment attenuates carbachol-mediated polyphosphoinositide hydrolysis in chick embryo neuronal cultures.
    Brain research, 1991, May-10, Volume: 548, Issue:1-2

    Topics: Analgesics; Animals; Bradykinin; Brain; Carbachol; Cells, Cultured; Chick Embryo; Endorphins; Enkephalin, Leucine-2-Alanine; Hydrolysis; Inositol; Inositol Phosphates; Kinetics; Neurons; Phosphatidylinositol Phosphates; Phosphatidylinositols; Receptors, Opioid

1991
Photoinactivation of the mu opioid receptor using a novel synthetic morphiceptin analog.
    European journal of pharmacology, 1987, Jul-23, Volume: 139, Issue:3

    Topics: Affinity Labels; Animals; Brain; Chemical Phenomena; Chemistry; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guinea Pigs; In Vitro Techniques; Light; Naloxone; Phenylalanine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1987
Characterization of opioid receptors modulating noradrenaline release in the hippocampus of the rabbit.
    Journal of neurochemistry, 1986, Volume: 46, Issue:6

    Topics: Animals; Benzomorphans; Clonidine; Cyclazocine; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Hippocampus; Morphine; Norepinephrine; Rabbits; Receptors, Opioid

1986
Characterization of opioid receptors in the cat carotid body involved in chemosensory depression in vivo.
    British journal of pharmacology, 1986, Volume: 88, Issue:4

    Topics: Animals; Carotid Body; Cats; Chemoreceptor Cells; Cyclazocine; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylketocyclazocine; Hypercapnia; Hypoxia; Peptide Fragments; Receptors, Opioid

1986
Further studies on opioids and hibernation: delta opioid receptor ligand selectively induced hibernation in summer-active ground squirrels.
    Life sciences, 1988, Volume: 43, Issue:19

    Topics: Analgesics; Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; Hibernation; Male; Morphine; Peptides; Proteins; Receptors, Opioid; Receptors, Opioid, delta; Reference Values; Sciuridae; Seasons; Structure-Activity Relationship

1988
Opiate binding sites in the chick, rabbit and goldfish retina.
    Brain research, 1985, Jul-22, Volume: 339, Issue:1

    Topics: Animals; Benzomorphans; Chickens; Dihydromorphine; Diprenorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Goldfish; Oligopeptides; Rabbits; Receptors, Opioid; Retina; Species Specificity

1985
Interaction of opiates with opioid binding sites in the bovine adrenal medulla: I. Interaction with delta and mu sites.
    Journal of neurochemistry, 1985, Volume: 45, Issue:3

    Topics: Adrenal Medulla; Animals; Binding Sites; Cattle; Cesium; Chlorides; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Ethylmaleimide; Kinetics; Lithium; Narcotics; Oligopeptides; Phospholipases A; Potassium; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium; Stereoisomerism

1985
Interaction of opiates with opioid binding sites in the bovine adrenal medulla: II. Interaction with kappa sites.
    Journal of neurochemistry, 1985, Volume: 45, Issue:3

    Topics: Adrenal Medulla; Animals; Benzomorphans; Binding Sites; Calcium; Cattle; Cyclazocine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethylketocyclazocine; Ethylmaleimide; Etorphine; Guinea Pigs; Kinetics; Lithium; Manganese; Narcotics; Oligopeptides; Phospholipases A; Potassium; Receptors, Opioid; Receptors, Opioid, kappa; Sodium; Stereoisomerism

1985
Regulation of ventilation and oxygen consumption by delta- and mu-opioid receptor agonists.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 59, Issue:3

    Topics: Animals; Blood Gas Analysis; Carbon Dioxide; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Hydrogen-Ion Concentration; Naloxone; Oxygen; Oxygen Consumption; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration

1985
Receptors for opioid peptides in the guinea-pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: Alkylation; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens

1985
Sex-dependent effects of neonatally administered morphiceptin and D-ala-D-leu-enkephalin on maze learning in rats.
    Behavioral and neural biology, 1985, Volume: 44, Issue:3

    Topics: Animals; Cerebral Ventricles; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Female; Learning; Male; Motor Activity; Rats; Reaction Time; Receptors, Opioid; Receptors, Opioid, mu; Sex Characteristics

1985
Opiate-induced seizures: a study of mu and delta specific mechanisms.
    Experimental neurology, 1986, Volume: 93, Issue:2

    Topics: Animals; Electroencephalography; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Morphine; Narcotics; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures

1986
Effect of endorphins on heart rate and blood pressure in adult dogs.
    The American journal of physiology, 1986, Volume: 250, Issue:5 Pt 2

    Topics: Animals; Atropine; Blood Pressure; Consciousness; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Heart; Heart Rate; Naloxone; Naltrexone

1986
Effects of delta and mu opiopeptides on the turnover and release of dopamine in rat striatum.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:1

    Topics: Animals; Corpus Striatum; Dopamine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Male; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1984
Kappa 3: a novel subtype of the kappa opioid site in bovine adrenal medulla, highly selective for Met-enkephalin-Arg6-Phe7.
    Neuropeptides, 1984, Volume: 5, Issue:1-3

    Topics: Adrenal Medulla; Animals; Cattle; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; In Vitro Techniques; Narcotics; Receptors, Opioid; Receptors, Opioid, kappa

1984
Analgesic activity of intracerebroventricular administration of morphiceptin and beta-casomorphins: correlation with the morphine (micro) receptor binding affinity.
    Life sciences, 1982, May-03, Volume: 30, Issue:18

    Topics: Analgesia; Animals; Binding, Competitive; Brain; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalin, Leucine-2-Alanine; Enkephalins; Injections, Intraventricular; Male; Naloxone; Rats; Receptors, Opioid

1982
Comparison of mu, delta, and kappa opiate binding sites in rat brain and spinal cord.
    Life sciences, 1984, Jan-16, Volume: 34, Issue:3

    Topics: Animals; Binding Sites; Brain; Cell Membrane; Cyclazocine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord

1984
Stimulation of phospholipase C by the cloned mu, delta and kappa opioid receptors via chimeric G alpha(q) mutants.
    The European journal of neuroscience, 1999, Volume: 11, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cloning, Molecular; COS Cells; DNA, Complementary; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Enzyme Activation; GTP-Binding Proteins; Mice; Naloxone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Fusion Proteins; Type C Phospholipases

1999