morphiceptin, n-me-phe(3)- has been researched along with naloxone in 26 studies
| Studies (morphiceptin, n-me-phe(3)-) | Trials (morphiceptin, n-me-phe(3)-) | Recent Studies (post-2010) (morphiceptin, n-me-phe(3)-) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 95 | 1 | 1 | 20,134 | 1,257 | 3,321 |
| Protein | Taxonomy | morphiceptin, n-me-phe(3)- (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (19.23) | 18.7374 |
| 1990's | 20 (76.92) | 18.2507 |
| 2000's | 1 (3.85) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Costa, EM; Hoffmann, BB; Loew, GH | 1 |
| Chang, KJ; Su, YF; Watkins, WD; Wong, CS | 1 |
| Caudle, RM; Chavkin, C; Simmons, ML; Wagner, JJ | 1 |
| Carboni, E; Di Chiara, G; Garau, L; Longoni, R; Melchiorri, P; Mulas, A; Spina, L | 1 |
| Burks, TF; Farmer, SC | 1 |
| Lewis, DV; Xie, CW | 1 |
| Burks, TF; Lemcke, PK; Shook, JE | 1 |
| Caudle, RM; Chavkin, C; Wagner, JJ | 1 |
| Hong, JS; Lee, PH; Lewis, DV; Mitchell, CL; Wilson, WA; Xie, CW | 1 |
| Burks, TF; Hruby, VJ; Lemcke, PK; Pelton, JT; Porreca, F; Shook, JE | 1 |
| Chavkin, C; Mailheau, S; Neumaier, JF | 1 |
| Haddad, GG; Schaeffer, JI | 1 |
| Chang, KJ; Leslie, JB; Russell, RD; Su, YF; Watkins, WD | 1 |
| Chang, KJ; Haddad, GG; Schaeffer, JI | 1 |
| Adler, MW; Geller, EB; Handler, CM; Mondgock, DJ; Zhao, SF | 1 |
| Bidlack, JM; Chung, NN; Dooley, CT; Houghten, RA; Pasternak, GW; Schiller, PW; Wilkes, BC | 1 |
| Macdonald, RL; Moises, HC; Rusin, KI | 1 |
| Hasegawa, A; Nagamatsu, K; Tagawa, Y; Uchida, S | 1 |
| Hauser, KF; Knapp, PE | 1 |
| Adler, MW; Handler, CM; Weinberg, R | 1 |
| Adler, MW; Chen, C; Geller, EB; Liu-Chen, LY; Xin, L | 1 |
| Harrison, LM; Kastin, AJ; Zadina, JE | 1 |
| Hauser, KF; Stiene-Martin, A; Zhou, R | 1 |
| Carney, JM; Harris-White, ME; Hauser, KF; Jackson, JA; Opanashuk, LA | 1 |
| Pol, O; Puig, MM; Valle, L | 1 |
26 other study(ies) available for morphiceptin, n-me-phe(3)- and naloxone
| Article | Year |
|---|---|
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
Opioid agonists binding and responses in SH-SY5Y cells.
Topics: Alprostadil; Analgesics; Cyclic AMP; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Fentanyl; GTP Phosphohydrolases; Humans; Meperidine; Morphinans; Naloxone; Narcotics; Oxymorphone; Receptors, Opioid; Receptors, Opioid, mu; Tumor Cells, Cultured | 1992 |
Continuous intrathecal opioid treatment abolishes the regulatory effects of magnesium and guanine nucleotides on mu opioid receptor binding in rat spinal membranes.
Topics: Animals; Cell Membrane; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Tolerance; Endorphins; Guanylyl Imidodiphosphate; Magnesium; Male; Morphine; Naloxone; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Spinal Cord; Virulence Factors, Bordetella | 1992 |
Endogenous opioid regulation of norepinephrine release in guinea pig hippocampus.
Topics: Animals; Calcium; Electric Stimulation; Endorphins; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Naloxone; Norepinephrine; Propranolol; Radioligand Assay | 1992 |
(D-Ala2)deltorphin II: D1-dependent stereotypies and stimulation of dopamine release in the nucleus accumbens.
Topics: Animals; Brain; Caudate Nucleus; Cerebral Ventricles; Dopamine; Endorphins; Functional Laterality; Indoles; Infusions, Parenteral; Injections, Intraventricular; Male; Morphinans; Motor Activity; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereotyped Behavior | 1991 |
Selective mu opioid is effective in mouse enteropooling model.
Topics: Animals; Biological Transport; Dinoprostone; Endorphins; Intestinal Mucosa; Intestine, Small; Male; Mice; Mice, Inbred ICR; Naloxone; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Opioid-mediated facilitation of long-term potentiation at the lateral perforant path-dentate granule cell synapse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electric Stimulation; Endorphins; Hippocampus; Male; Naloxone; Narcotics; Neural Pathways; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, mu; Synapses | 1991 |
Spinally mediated opioid antidiarrheal effects.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Antidiarrheals; Body Weight; Diarrhea; Dinoprostone; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gastrointestinal Transit; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotics; Pyrrolidines; Spinal Cord | 1991 |
Endogenous opioids released from perforant path modulate norepinephrine actions and inhibitory postsynaptic potentials in guinea pig CA3 pyramidal cells.
Topics: Animals; Electric Stimulation; Electrophysiology; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Hippocampus; Male; Membrane Potentials; Naloxone; Norepinephrine; Propranolol; Pyramidal Tracts; Synapses | 1991 |
Opioid-induced epileptiform bursting in hippocampal slices: higher susceptibility in ventral than dorsal hippocampus.
Topics: Animals; Electrophysiology; Endorphins; Hippocampus; In Vitro Techniques; Male; Naloxone; Rats; Rats, Inbred F344; Receptors, Opioid; Seizures | 1990 |
Mu opioid antagonist properties of a cyclic somatostatin octapeptide in vivo: identification of mu receptor-related functions.
Topics: Analgesia; Analgesics; Animals; Behavior, Animal; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gastrointestinal Motility; Hot Temperature; Kinetics; Male; Mice; Mice, Inbred ICR; Naloxone; Receptors, Opioid; Receptors, Opioid, mu; Somatostatin | 1987 |
Opioid receptor-mediated responses in the dentate gyrus and CA1 region of the rat hippocampus.
Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; GABA Antagonists; Hippocampus; Interneurons; Naloxone; Oligopeptides; Rats; Receptors, Opioid | 1988 |
Regulation of ventilation and oxygen consumption by delta- and mu-opioid receptor agonists.
Topics: Animals; Blood Gas Analysis; Carbon Dioxide; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Hydrogen-Ion Concentration; Naloxone; Oxygen; Oxygen Consumption; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration | 1985 |
Continuous intrathecal opioid analgesia: tolerance and cross-tolerance of mu and delta spinal opioid receptors.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Injections, Spinal; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 1987 |
Opposite effects of the delta- and mu-opioid receptor agonists on ventilation in conscious adult dogs.
Topics: Animals; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Morphine; Naloxone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration; Respiratory Center | 1984 |
Interaction between opioid agonists and neurotensin on thermoregulation in the rat. I. Body temperature.
Topics: Animals; Body Temperature Regulation; Endorphins; Male; Naloxone; Neurotensin; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 1995 |
An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library.
Topics: Amino Acid Sequence; Analgesics; Animals; Brain; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; Injections, Intraventricular; Male; Mice; Models, Molecular; Molecular Sequence Data; Naloxone; Opioid Peptides; Pain Measurement; Protein Conformation; Rats; Receptors, Opioid, mu; Stereoisomerism | 1994 |
Mu- and kappa-opioid receptors selectively reduce the same transient components of high-threshold calcium current in rat dorsal root ganglion sensory neurons.
Topics: Analgesics; Animals; Benzeneacetamides; Calcium; Calcium Channels; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Evoked Potentials; Ganglia, Spinal; In Vitro Techniques; Naloxone; Naltrexone; Narcotic Antagonists; Neurons, Afferent; Pyrrolidines; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reference Values; Sensitivity and Specificity | 1994 |
Mouse brain opioid receptor identification by direct ultraviolet photoaffinity labeling.
Topics: Affinity Labels; Animals; Binding Sites; Dithiothreitol; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Morphine; Naloxone; Receptors, Opioid; Tritium; Tyrosine; Ultraviolet Rays | 1993 |
mu-Opioid receptor activation enhances DNA synthesis in immature oligodendrocytes.
Topics: Animals; Cell Division; Cells, Cultured; Cellular Senescence; Cloning, Molecular; DNA; Endorphins; Epitope Mapping; Immunohistochemistry; Mice; Naloxone; Narcotic Antagonists; Oligodendroglia; Receptors, Opioid, mu | 1996 |
The effect of selective and nonselective opioids on body temperature in cold-acclimated rats.
Topics: Acclimatization; Animals; Body Temperature; Body Temperature Regulation; Cold Temperature; Endorphins; Male; Morphine; Naloxone; Narcotics; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1997 |
Substance P release in the rat periaqueductal gray and preoptic anterior hypothalamus after noxious cold stimulation: effect of selective mu and kappa opioid agonists.
Topics: Animals; Cold Temperature; Dynorphins; Endorphins; Hypothalamus; Microdialysis; Naloxone; Peptide Fragments; Periaqueductal Gray; Physical Stimulation; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance P | 1997 |
Tyr-W-MIF-1 attenuates down-regulation of opiate receptors in SH-SY5Y human neuroblastoma cells.
Topics: Culture Media; Down-Regulation; Endorphins; Enkephalin, Methionine; Humans; Morphine; MSH Release-Inhibiting Hormone; Naloxone; Neuroblastoma; Neurons; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured; Up-Regulation | 1998 |
Regional, developmental, and cell cycle-dependent differences in mu, delta, and kappa-opioid receptor expression among cultured mouse astrocytes.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Age Factors; Analgesics; Analgesics, Non-Narcotic; Animals; Antibody Specificity; Astrocytes; Brain Chemistry; Calcium; Cell Cycle; Cell Division; Cells, Cultured; Cerebellum; Cerebral Cortex; Corpus Striatum; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Flow Cytometry; Hippocampus; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1998 |
Opioids disrupt Ca2+ homeostasis and induce carbonyl oxyradical production in mouse astrocytes in vitro: transient increases and adaptation to sustained exposure.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Animals; Astrocytes; Calcium; Drug Tolerance; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Homeostasis; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Narcotics; Oxidative Stress; Reactive Oxygen Species; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1998 |
Effects of mu-opioid receptor agonists on intestinal secretion and permeability during acute intestinal inflammation in mice.
Topics: Acute Disease; Animals; Croton Oil; Dose-Response Relationship, Drug; Endorphins; Enteritis; Fentanyl; Intestinal Mucosa; Male; Mice; Morphine; Naloxone; Permeability; Receptors, Opioid, mu | 2000 |