morin-5--sulfonic-acid and malonic-acid

morin-5--sulfonic-acid has been researched along with malonic-acid* in 1 studies

Other Studies

1 other study(ies) available for morin-5--sulfonic-acid and malonic-acid

ArticleYear
Syntheses, crystal structures and antioxidant study of Zn(II) complexes with morin-5'-sulfonic acid (MSA).
    Journal of inorganic biochemistry, 2014, Volume: 141

    The study of modified synthetic procedure of water soluble morin-5'-sulfonic acid sodium salt (NaMSA) involving less aggressive chemicals and carried out at mild conditions was described. The NaMSA salt is a convenient source of anionic morin-5'-sulfonic ligand (MSA) in ion exchange reactions. The coordination ability of MSA ligand towards the zinc cations was investigated in aqueous solution and in solid state. Novel zinc complexes of morin-5'-sulfonate were obtained by a reaction of Zn(NO3)2 with morin-5'-sulfonate in water. Resulting compounds were characterized by single-crystal X-ray diffraction analysis, as well as spectral and thermal methods. The coordination interaction, hydrogen bond and π-π stacking lead to the formation of a 1D chain or 3D coordination polymers. The antioxidant activity of the Zn(II)-MSA complexes was evaluated by means of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging method. In this work, we have shown that the studied compounds are more effective free radical scavengers than the natural flavonoids like plain morin.

    Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cisplatin; Coordination Complexes; Crystallography, X-Ray; Female; Flavonoids; Humans; Inhibitory Concentration 50; Male; Malonates; Mice; NIH 3T3 Cells; Organoplatinum Compounds; Pyrimidines; Structure-Activity Relationship; Sulfonic Acids; Zinc

2014