monomethyl-auristatin-e has been researched along with carfilzomib* in 1 studies
1 other study(ies) available for monomethyl-auristatin-e and carfilzomib
Article | Year |
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Carfilzomib Is Not an Appropriate Payload of Antibody-Drug Conjugates Due to Rapid Inactivation by Lysosomal Enzymes.
Carfilzomib (CFZ) is a proteasome inhibitor used for oncology indications including treating multiple myeloma. CFZ is a potent cytotoxic agent with an IC Topics: Antibodies, Monoclonal; Antineoplastic Agents; Cathepsin B; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Feasibility Studies; Humans; Immunoconjugates; Lysosomes; Neoplasms; Oligopeptides; Receptor, ErbB-2; Sialic Acid Binding Ig-like Lectin 2 | 2019 |