monoisoamyl-2,3-dimercaptosuccinate has been researched along with succimer in 48 studies
Studies (monoisoamyl-2,3-dimercaptosuccinate) | Trials (monoisoamyl-2,3-dimercaptosuccinate) | Recent Studies (post-2010) (monoisoamyl-2,3-dimercaptosuccinate) | Studies (succimer) | Trials (succimer) | Recent Studies (post-2010) (succimer) |
---|---|---|---|---|---|
53 | 0 | 19 | 1,665 | 57 | 269 |
Protein | Taxonomy | monoisoamyl-2,3-dimercaptosuccinate (IC50) | succimer (IC50) |
---|---|---|---|
Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 1.72 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 9 (18.75) | 18.2507 |
2000's | 19 (39.58) | 29.6817 |
2010's | 15 (31.25) | 24.3611 |
2020's | 5 (10.42) | 2.80 |
Authors | Studies |
---|---|
Holscher, MA; Jones, MM; Singh, PK; Xu, C | 1 |
Eybl, V; Jones, MM; Kotyzová, D; Koutenský, J; Singh, PK | 1 |
Blanusa, M; Jones, MM; Kostial, K; Piasek, M; Singh, PK | 2 |
Blanusa, M; Jones, MM; Kargacin, B; Kostial, K; Piasek, M; Singh, PK | 1 |
Bellés, M; Domingo, JL; Gómez, M; Jones, MM; Sánchez, DJ; Singh, PK | 1 |
Domingo, JL; Gómez, M; Jones, MM; Llobet, JM; Sánchez, DJ; Singh, PK | 1 |
Carter, CE; Dietrich, MS; Johnson, JE; Jones, MM; Singh, PK; Xu, C; Yan, H | 1 |
Arora, U; Flora, GJ; Seth, PK | 1 |
Chauhan, RS; Dubey, R; Flora, SJ; Jaiswal, DK; Kannan, GM; Pant, BP | 1 |
Flora, SJ; Jaiswal, DK; Kannan, GM; Pant, BP | 2 |
Prasad, S; Siddiqui, MK; Singh, S; Srivastava, S; Tandon, SK | 1 |
Flora, SJ; Mehta, A; Pande, M | 1 |
Chatterjee, M; Dwivedi, VK; Khandekar, K; Mathur, N; Prasad, S; Singh, S; Tandon, SK | 1 |
Bhaskar, AS; Dube, SN; Flora, SJ; Kannan, GM; Mehta, A; Pant, BP; Rao, PV | 1 |
Flora, SJ; Kannan, GM | 1 |
Bhadauria, S; Flora, SJ | 2 |
Flora, SJ; Saxena, G | 1 |
Bhadauria, S; Dhaked, RK; Flora, SJ; Pant, SC | 1 |
Flora, SJ; Mehta, A; Saxena, G | 1 |
Flora, SJ; Modi, M | 1 |
Flora, SJ; Gautam, P; Jatav, PC; Mehta, A; Pathak, U | 1 |
Bhadauria, S; Flora, SJ; Kannan, GM; Singh, N | 1 |
Flora, SJ; Mehta, A; Mishra, D; Pachauri, V; Saxena, G | 1 |
Flora, SJ; Mehta, A | 1 |
Baran, EJ; Williams, PA; Zinczuk, J | 1 |
Flora, SJ; Gupta, R; Kushwah, P; Mishra, D; Pant, SC; Satish, HT | 1 |
Bhatt, K; Dwivedi, N; Flora, SJ; Kushwah, PK; Pachauri, V | 1 |
Binukumar, BK; Dwivedi, N; Flora, SJ; Gill, KD; Mehta, A; Yadav, A | 1 |
Badisa, RB; Badisa, VL; Buggs, R; Darling-Reed, SF; Ikediobi, CO; Latinwo, LM; Odewumi, CO; Owens, MA | 1 |
Bhadauria, S; Flora, SJ; Pachauri, V; Yadav, A | 1 |
Acharya, S; Basu, AK; Bhattacharya, D; Chatterjee, S; Chaudhuri, S; Dasgupta, S; Flora, SJ; Kumar, P; Singh, MK | 1 |
Dubey, M; Flora, SJ; Kushwaha, P; Pachauri, V; Yadav, A | 1 |
Flora, SJ; Mehta, A; Mishra, D; Pachauri, V | 1 |
Flora, SJ; Ram Kumar, M; Reddy, GR | 1 |
Flora, SJ; Kushwaha, P; Pachauri, V; Srivastava, P; Yadav, A | 1 |
Gottipolu, RR; Kadeyala, PK; Sannadi, S | 2 |
Babbar, AK; Flora, SJ; Kaushik, MP; Kushwaha, P; Lomash, V; Mathur, R; Mishra, AK; Pathak, U; Samim, M; Yadav, A | 1 |
Flora, SJS; Kushwaha, P; Samim, M; Yadav, A | 1 |
Davuljigari, CB; Kumar, KP; Reddy, GR; Saritha, S | 1 |
Flora, SJS; Sathua, K; Srivastava, S | 1 |
Flora, SJS; Patwa, J; Sharma, A; Thakur, A | 1 |
Flora, SJS; Kumar, P; Naqvi, S | 1 |
Flora, SJS; Sachdeva, S; Sharma, A | 1 |
Flora, SJS; Jain, K; Panghal, A; Patwa, J | 1 |
2 review(s) available for monoisoamyl-2,3-dimercaptosuccinate and succimer
Article | Year |
---|---|
Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review.
Topics: Acetylcysteine; Animals; Antioxidants; Arsenic Poisoning; Ascorbic Acid; Chelating Agents; Chelation Therapy; Dimercaprol; Drug Therapy, Combination; Environmental Pollutants; Humans; Melatonin; Oxidative Stress; Plant Extracts; Selenium; Succimer; Taurine; Thioctic Acid; Vitamin E; Zinc | 2007 |
Chemistry, Pharmacology, and Toxicology of Monoisoamyl Dimercaptosuccinic Acid: A Chelating Agent for Chronic Metal Poisoning.
Topics: Animals; Antidotes; Antioxidants; Arsenic; Arsenic Poisoning; Cadmium; Chelating Agents; Heavy Metal Poisoning; Mercury; Rats; Rats, Wistar; Succimer | 2022 |
46 other study(ies) available for monoisoamyl-2,3-dimercaptosuccinate and succimer
Article | Year |
---|---|
Effect of monoisoamyl meso-2,3-dimercaptosuccinate on the pathology of acute cadmium intoxication.
Topics: Acute Disease; Animals; Cadmium; Cadmium Chloride; Chelating Agents; Chlorides; Cysteine; Drug Combinations; Kidney; Male; Rats; Rats, Wistar; Succimer; Testis | 1995 |
Effect of chelators, monoisoamyl meso-2,3-dimercaptosuccinate and N-(4-methylbenzyl)-4-O-(beta-D-galactopyranosyl)-D-glucamine-N-carbodit hioate, on cadmium and essential element levels in mice.
Topics: Animals; Brain; Cadmium; Chelating Agents; Disaccharides; Kidney; Liver; Male; Mice; Mice, Inbred ICR; Succimer; Testis; Thiocarbamates | 1995 |
Reduction of lead retention by mono-3-methylbutan-1-yl meso-2,3-dimercaptosuccinate in suckling rats.
Topics: Animals; Animals, Suckling; Bone and Bones; Brain; Chelating Agents; Kidney; Lead; Liver; Rats; Rats, Wistar; Spectrophotometry, Atomic; Succimer | 1995 |
Monoisoamyl meso-2,3-dimercaptosuccinate as a delayed treatment for mercury removal in rats.
Topics: Aging; Animals; Animals, Suckling; Chelation Therapy; Mercury Poisoning; Rats; Rats, Wistar; Succimer; Time Factors | 1994 |
Assessment of the protective activity of monisoamyl meso-2,3-dimercaptosuccinate against methylmercury-induced maternal and embryo/fetal toxicity in mice.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Chelating Agents; Chelation Therapy; Disease Models, Animal; Embryonic and Fetal Development; Female; Fetal Death; Male; Methylmercury Compounds; Mice; Pregnancy; Succimer | 1996 |
Effects of monoisoamyl meso-2,3-dimercaptosuccinate on arsenite-induced maternal and developmental toxicity in mice.
Topics: Animals; Arsenites; Chelating Agents; Female; Injections, Subcutaneous; Maternal Behavior; Maternal Welfare; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Pregnancy; Succimer; Time Factors | 1995 |
Prolonged oral treatment with two monoesters of meso-2,3-dimercaptosuccinic acid for depleting inorganic mercury retention in suckling rats.
Topics: Administration, Oral; Animals; Animals, Suckling; Brain; Chelating Agents; Female; Isotope Labeling; Kidney; Liver; Male; Mercury; Rats; Rats, Wistar; Succimer; Tissue Distribution | 1995 |
Cadmium-induced apoptosis in the urogenital organs of the male rat and its suppression by chelation.
Topics: Animals; Apoptosis; Biotin; Cadmium Chloride; Chelating Agents; Chromatin; DNA Fragmentation; DNA Nucleotidylexotransferase; Enzyme-Linked Immunosorbent Assay; Epididymis; Injections, Intraperitoneal; Kidney; Male; Mutagens; Prostate; Rats; Rats, Wistar; Seminal Vesicles; Succimer; Uridine Triphosphate; Urinary Bladder; Urogenital System | 1997 |
Influence of combined therapeutic potential of meso 2,3-dimercaptosuccinic acid and calcium disodium edetate on lead-induced testicular alterations in rats.
Topics: Animals; Chelating Agents; Edetic Acid; Lead; Male; Rats; Succimer; Testicular Neoplasms; Testis | 1999 |
Meso 2,3-dimercaptosuccinic acid (DMSA) and monoisoamyl DMSA effect on gallium arsenide induced pathological liver injury in rats.
Topics: Alanine Transaminase; Animals; Arsenicals; Aspartate Aminotransferases; Catalase; Chelating Agents; Chemical and Drug Induced Liver Injury; Gallium; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver Function Tests; Male; Metals; Oxidation-Reduction; Oxidative Stress; Porphobilinogen Synthase; Rats; Succimer; Superoxide Dismutase | 2002 |
Combined administration of oxalic acid, succimer and its analogue for the reversal of gallium arsenide-induced oxidative stress in rats.
Topics: Aminolevulinic Acid; Animals; Arsenicals; Chelating Agents; Copper; Drug Therapy, Combination; Gallium; Glutathione; Glutathione Disulfide; Kidney; Liver; Male; Malondialdehyde; Oxalic Acid; Oxidative Stress; Porphobilinogen Synthase; Protoporphyrins; Rats; Rats, Wistar; Spleen; Succimer; Tissue Distribution; Zinc | 2002 |
Reversal of lead-induced oxidative stress by chelating agent, antioxidant, or their combination in the rat.
Topics: Acetylcysteine; Aminolevulinic Acid; Animals; Antioxidants; Brain; Catalase; Chelating Agents; Free Radical Scavengers; Glutathione; Kidney; Lead; Lead Poisoning; Male; Malondialdehyde; Oxidative Stress; Rats; Succimer | 2002 |
The efficacy of monoisoamyl ester of dimercaptosuccinic acid in chronic experimental arsenic poisoning in mice.
Topics: Administration, Oral; Animals; Arsenic Poisoning; Disease Models, Animal; Infusions, Parenteral; Kidney; Liver; Male; Mice; Oxidative Stress; Succimer | 2003 |
Beneficial effect of combined administration of some naturally occurring antioxidants (vitamins) and thiol chelators in the treatment of chronic lead intoxication.
Topics: Animals; Antidotes; Antioxidants; Ascorbic Acid; Chelating Agents; Cysteinyldopa; Disease Models, Animal; Drug Therapy, Combination; Lead Poisoning; Male; Oxidative Stress; Porphobilinogen Synthase; Protoporphyrins; Rats; Rats, Wistar; Succimer; Treatment Outcome; Vitamin E | 2003 |
Reversal of cadmium induced oxidative stress by chelating agent, antioxidant or their combination in rat.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Brain; Cadmium Chloride; Cadmium Poisoning; Catalase; Chelating Agents; Drug Synergism; Drug Therapy, Combination; Glutathione; Liver; Male; Malondialdehyde; Mannitol; Oxidative Stress; Rats; Succimer; Superoxide Dismutase | 2003 |
Therapeutic potential of monoisoamyl and monomethyl esters of meso 2,3-dimercaptosuccinic acid in gallium arsenide intoxicated rats.
Topics: Aminolevulinic Acid; Animals; Antidotes; Arsenic Poisoning; Arsenicals; Biomarkers; Chelating Agents; Chelation Therapy; Comet Assay; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Gallium; Injections, Intraperitoneal; Liver; Male; Protoporphyrins; Rats; Rats, Wistar; Succimer; Treatment Outcome | 2004 |
Chronic arsenic poisoning in the rat: treatment with combined administration of succimers and an antioxidant.
Topics: Animals; Antioxidants; Arsenic; Arsenic Poisoning; Ascorbic Acid; Brain Chemistry; Chelating Agents; Drug Interactions; Drug Therapy, Combination; Heme; Male; Oxidative Stress; Rats; Rats, Wistar; Succimer; Tissue Distribution | 2004 |
Arsenic induced inhibition of delta-aminolevulinate dehydratase activity in rat blood and its response to meso 2,3-dimercaptosuccinic acid and monoisoamyl DMSA.
Topics: Administration, Oral; Animals; Arsenic Poisoning; Arsenicals; Enzyme Inhibitors; Injections, Intraperitoneal; Male; Mice; Porphobilinogen Synthase; Rats; Succimer | 2004 |
Lead-induced oxidative stress and hematological alterations and their response to combined administration of calcium disodium EDTA with a thiol chelator in rats.
Topics: Animals; Brain; Chelating Agents; Drug Therapy, Combination; Edetic Acid; Glutathione; Hemoglobins; Kidney; Lead; Lead Poisoning; Male; Metals; Oxidative Stress; Porphobilinogen Synthase; Protoporphyrins; Rats; Rats, Wistar; Succimer; Unithiol | 2004 |
Arsenic induced blood and brain oxidative stress and its response to some thiol chelators in rats.
Topics: 5-Aminolevulinate Synthetase; Animals; Arsenic; Arsenic Poisoning; Chelating Agents; DNA Damage; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Male; Oxidative Stress; Porphobilinogen Synthase; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Unithiol | 2005 |
Response of arsenic-induced oxidative stress, DNA damage, and metal imbalance to combined administration of DMSA and monoisoamyl-DMSA during chronic arsenic poisoning in rats.
Topics: Animals; Antidotes; Arsenic Poisoning; Chelating Agents; Copper; DNA Damage; Drug Therapy, Combination; Erythrocytes; Kidney; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Succimer; Zinc | 2007 |
Reversal of lead-induced neuronal apoptosis by chelation treatment in rats: role of reactive oxygen species and intracellular Ca(2+).
Topics: Animals; Apoptosis; Behavior, Animal; Brain; Calcium; Chelating Agents; Edetic Acid; Lead; Male; Mitochondria; Neurons; Neurotransmitter Agents; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer | 2007 |
Combined administration of iron and monoisoamyl-DMSA in the treatment of chronic arsenic intoxication in mice.
Topics: Animals; Arsenic; Arsenic Poisoning; Brain; Chronic Disease; Drug Therapy, Combination; Iron; Kidney; Liver; Male; Mice; Oxidative Stress; Succimer; Zinc | 2007 |
Essential metal status, prooxidant/antioxidant effects of MiADMSA in male rats: age-related effects.
Topics: Aging; Animals; Antioxidants; Chelating Agents; Copper; Glutathione; Glutathione Disulfide; Hemoglobins; Iron; Magnesium; Male; Metals; Oxidants; Porphobilinogen Synthase; Protoporphyrins; Rats; Rats, Wistar; Succimer; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Zinc | 2007 |
Combinational chelation therapy abrogates lead-induced neurodegeneration in rats.
Topics: Animals; Antioxidants; Apoptosis; Behavior, Animal; Biogenic Amines; Calcium; Captopril; Chelating Agents; Cytochromes c; Disease Models, Animal; DNA Damage; Drug Therapy, Combination; Exploratory Behavior; Lead Poisoning, Nervous System; Learning; Male; Membrane Potential, Mitochondrial; Memory; Mitochondria; Motor Activity; Nerve Degeneration; Neurons; Nitric Oxide; Organometallic Compounds; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer | 2009 |
Monoisoamyl dimercaptosuccinic acid abrogates arsenic-induced developmental toxicity in human embryonic stem cell-derived embryoid bodies: comparison with in vivo studies.
Topics: Animals; Arsenites; Cell Culture Techniques; Cell Differentiation; Cell Line; Cell Survival; Chelating Agents; Congenital Abnormalities; Embryonic Development; Embryonic Stem Cells; Environmental Pollutants; Female; Gene Expression Regulation, Developmental; Germ Layers; Humans; Pregnancy; Rats; Rats, Wistar; Sodium Compounds; Succimer; Toxicity Tests | 2009 |
On the interaction of vanadium species with the monoisoamyl ester of meso-2,3-dimercaptosuccinic acid.
Topics: Chelating Agents; Hydrogen-Ion Concentration; Succimer; Vanadium | 2010 |
Co-administration of monoisoamyl dimercaptosuccinic acid and Moringa oleifera seed powder protects arsenic-induced oxidative stress and metal distribution in mice.
Topics: Animals; Antioxidants; Arsenic; Arsenic Poisoning; Body Weight; Brain; Chelating Agents; Drinking; Eating; Free Radicals; Glutathione; Kidney; Liver; Male; Metals; Mice; Moringa oleifera; Oxidative Stress; Seeds; Succimer; Tissue Distribution | 2009 |
Co-administration of meso 2,3-dimercaptosuccinic acid monoesters reduces arsenic concentration and oxidative stress in gallium arsenide exposed rats.
Topics: Aminolevulinic Acid; Animals; Arsenic; Arsenic Poisoning; Arsenicals; Catalase; Copper; Gallium; Glutathione; Heme; Kidney; Lipid Peroxidation; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer; Superoxide Dismutase; Transaminases; Zinc | 2011 |
MiADMSA reverses impaired mitochondrial energy metabolism and neuronal apoptotic cell death after arsenic exposure in rats.
Topics: Animals; Apoptosis; Arsenic Poisoning; Brain; Cells, Cultured; Chelating Agents; Electron Transport; Electron Transport Complex IV; Energy Metabolism; Male; Membrane Potential, Mitochondrial; Mitochondria; NADH Dehydrogenase; Neurons; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer; Succinate Dehydrogenase | 2011 |
Mitigative action of monoisoamyl-2,3-dimercaptosuccinate (MiADMS) against cadmium-induced damage in cultured rat normal liver cells.
Topics: Animals; Antioxidants; Cadmium; Catalase; Cell Cycle Checkpoints; Cell Line; Cell Survival; Chelating Agents; Environmental Pollutants; Glutathione Peroxidase; Glutathione Reductase; Hepatocytes; Rats; S Phase; Succimer | 2011 |
Monoisoamyl 2, 3-dimercaptosuccinic acid (MiADMSA) demonstrates higher efficacy by oral route in reversing arsenic toxicity: a pharmacokinetic approach.
Topics: Administration, Oral; Animals; Arsenic; Arsenic Poisoning; Chelating Agents; Chronic Disease; Copper; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Kidney; Liver; Liver Function Tests; Male; Oxidative Stress; Rats; Rats, Wistar; Succimer; Zinc | 2012 |
Therapeutic profile of T11TS vs. T11TS+MiADMSA: a hunt for a more effective therapeutic regimen for arsenic exposure.
Topics: Animals; Apoptosis; Arsenic; Arsenic Poisoning; CD2 Antigens; Cell Transformation, Neoplastic; Chelating Agents; Chelation Therapy; Cytokines; Drug Therapy, Combination; Environmental Exposure; Lymphocytes; Mice; Oxidative Stress; Succimer | 2012 |
Monensin potentiates lead chelation efficacy of MiADMSA in rat brain post chronic lead exposure.
Topics: Animals; Antioxidants; Biomarkers; Brain; Chelating Agents; DNA Damage; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Kidney; Lead; Male; Monensin; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
Arsenic induced neuronal apoptosis in guinea pigs is Ca2+ dependent and abrogated by chelation therapy: role of voltage gated calcium channels.
Topics: Animals; Apoptosis; Arsenic Poisoning; Arsenites; bcl-2-Associated X Protein; Calcium; Calcium Channels, L-Type; Caspase 3; Chelating Agents; Cytoprotection; Disease Models, Animal; Drug Therapy, Combination; Guinea Pigs; Kinetics; Male; Membrane Potential, Mitochondrial; Neurons; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Sodium Compounds; Succimer | 2013 |
Monoisoamyl 2,3-dimercaptosuccinic acid attenuates arsenic induced toxicity: behavioral and neurochemical approach.
Topics: Animals; Arsenic Poisoning; Behavior, Animal; Brain; Catalase; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hand Strength; Male; Maze Learning; Mitochondria; Motor Activity; Neuroprotective Agents; Rats; Rats, Wistar; Succimer; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2013 |
MiADMSA protects arsenic-induced oxidative stress in human keratinocyte 'HaCaT' cells.
Topics: Arsenic; Cell Line; Dose-Response Relationship, Drug; Humans; Keratinocytes; Oxidative Stress; Succimer | 2013 |
Reversal effect of monoisoamyl dimercaptosuccinic acid (MiADMSA) for arsenic and lead induced perturbations in apoptosis and antioxidant enzymes in developing rat brain.
Topics: Age Factors; Animals; Animals, Newborn; Antioxidants; Apoptosis; Arsenates; Brain; Catalase; Embryo, Mammalian; Female; Lead; Male; Malondialdehyde; Oxidative Stress; Pregnancy; Rats; Rats, Wistar; Succimer; Superoxide Dismutase | 2013 |
Alterations in apoptotic caspases and antioxidant enzymes in arsenic exposed rat brain regions: reversal effect of essential metals and a chelating agent.
Topics: Animals; Antioxidants; Apoptosis; Arsenic; Brain; Calcium; Caspases; Chelating Agents; Lipid Peroxidation; Metals; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Succimer; Zinc | 2013 |
Nanoencapsulation of DMSA monoester for better therapeutic efficacy of the chelating agent against arsenic toxicity.
Topics: Animals; Arsenic; Arsenic Poisoning; Brain; Chelating Agents; Drug Carriers; Kidney; Liver; Male; Mice; Nanoparticles; Rabbits; Rats; Rats, Wistar; Succimer | 2014 |
Combinatorial drug delivery strategy employing nano-curcumin and nano-MiADMSA for the treatment of arsenic intoxication in mouse.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Arsenic; Arsenic Poisoning; Curcumin; Deoxyguanosine; Drug Carriers; Drug Synergism; Enzymes; Glutathione; Liver; Male; Mice; Nanoparticles; Oxidative Stress; Reactive Oxygen Species; Succimer | 2018 |
Effects of combined arsenic and lead exposure on the brain monoaminergic system and behavioral functions in rats: Reversal effect of MiADMSA.
Topics: Animals; Arsenic; Behavior, Animal; Biogenic Monoamines; Brain; Exploratory Behavior; Female; Lead; Male; Motor Activity; Neuroprotective Agents; Neurotoxins; Rats; Rats, Wistar; Succimer | 2019 |
MiADMSA ameliorate arsenic induced urinary bladder carcinogenesis in vivo and in vitro.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Arsenites; Cacodylic Acid; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; Chelating Agents; DNA Damage; Humans; Male; Matrix Metalloproteinase 9; Nitrosative Stress; Rats, Sprague-Dawley; Sodium Compounds; Succimer; Survivin; Urinary Bladder Neoplasms | 2020 |
Monoisoamyl DMSA reduced copper-induced neurotoxicity by lowering 8-OHdG level, amyloid beta and Tau protein expressions in Sprague-Dawley rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amyloid beta-Peptides; Animals; Brain; Brain Chemistry; Copper; Male; Molecular Docking Simulation; Neuroprotective Agents; Rats, Sprague-Dawley; Succimer; tau Proteins | 2020 |
Comparative efficacy of Nano and Bulk Monoisoamyl DMSA against arsenic-induced neurotoxicity in rats.
Topics: Animals; Antioxidants; Arsenic Poisoning; Arsenites; Behavior, Animal; Biomarkers; Brain; Chelating Agents; Disease Models, Animal; Drug Compounding; Lipids; Male; Motor Activity; Nanoparticles; Oxidative Stress; Rats, Transgenic; Sodium Compounds; Succimer | 2020 |
MiADMSA abrogates sodium tungstate-induced oxidative stress in rats.
Topics: Animals; Antidotes; Arsenic; Biomarkers; Chelating Agents; Glutathione Disulfide; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Succimer; Thiobarbituric Acid Reactive Substances; Tungsten | 2022 |