monoiodotyrosine and 9-aminoacridine-4-carboxamide

monoiodotyrosine has been researched along with 9-aminoacridine-4-carboxamide* in 1 studies

Other Studies

1 other study(ies) available for monoiodotyrosine and 9-aminoacridine-4-carboxamide

Article	Year
Haloperidol-succinylglycyl[125I]iodotyrosine, a novel iodinated ligand for dopamine D2 receptors. FEBS letters, 1987, Nov-30, Volume: 224, Issue:2 A novel radioiodinated ligand of the butyrophenone type has been synthesized for the quantification and characterization of dopamine D2 receptors. This haloperidol-derived ligand, haloperidol-succinylglycyl[125I]iodotyrosine ([125I]HSGTI), binds rapidly (equilibrium is reached within 30 min, at 10 pM and 37 degrees C) and with high affinity (Kd = 0.3 nM) to bovine striatal membranes. Its pharmacology, determined by competitive displacement with dopaminergic and non-dopaminergic drugs, is characteristic of binding to dopamine D2 receptors. Topics: Aminoacridines; Animals; Binding, Competitive; Cattle; Cell Membrane; Corpus Striatum; Haloperidol; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Ligands; Monoiodotyrosine; Receptors, Dopamine	1987

Article

Year

Haloperidol-succinylglycyl[125I]iodotyrosine, a novel iodinated ligand for dopamine D2 receptors.

FEBS letters, 1987, Nov-30, Volume: 224, Issue:2

A novel radioiodinated ligand of the butyrophenone type has been synthesized for the quantification and characterization of dopamine D2 receptors. This haloperidol-derived ligand, haloperidol-succinylglycyl[125I]iodotyrosine ([125I]HSGTI), binds rapidly (equilibrium is reached within 30 min, at 10 pM and 37 degrees C) and with high affinity (Kd = 0.3 nM) to bovine striatal membranes. Its pharmacology, determined by competitive displacement with dopaminergic and non-dopaminergic drugs, is characteristic of binding to dopamine D2 receptors.

Topics: Aminoacridines; Animals; Binding, Competitive; Cattle; Cell Membrane; Corpus Striatum; Haloperidol; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Ligands; Monoiodotyrosine; Receptors, Dopamine

1987