Page last updated: 2024-08-22

monoethylglycinexylidide and fluvoxamine

monoethylglycinexylidide has been researched along with fluvoxamine in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	2 (66.67)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Backman, JT; Kivistö, KT; Neuvonen, PJ; Taavitsainen, P; Wang, JS; Wen, X	1
De Martin, S; Floreani, M; Orlando, R; Padrini, R; Palatini, P; Piccoli, P	1
Isohanni, MH; Neuvonen, PJ; Olkkola, KT	1

Trials

2 trial(s) available for monoethylglycinexylidide and fluvoxamine

Article	Year
Cytochrome P450 1A2 is a major determinant of lidocaine metabolism in vivo: effects of liver function. Clinical pharmacology and therapeutics, 2004, Volume: 75, Issue:1 Topics: Anti-Arrhythmia Agents; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP1A2 Inhibitors; Double-Blind Method; Fluvoxamine; Humans; Infusions, Intravenous; Lidocaine; Liver; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index	2004
Effect of fluvoxamine and erythromycin on the pharmacokinetics of oral lidocaine. Basic & clinical pharmacology & toxicology, 2006, Volume: 99, Issue:2 Topics: Administration, Oral; Adult; Anesthetics, Local; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Erythromycin; Female; Fluvoxamine; Half-Life; Humans; Lidocaine; Male; Metabolic Clearance Rate; Nausea	2006

Article

Year

Cytochrome P450 1A2 is a major determinant of lidocaine metabolism in vivo: effects of liver function.

Clinical pharmacology and therapeutics, 2004, Volume: 75, Issue:1

Topics: Anti-Arrhythmia Agents; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP1A2 Inhibitors; Double-Blind Method; Fluvoxamine; Humans; Infusions, Intravenous; Lidocaine; Liver; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index

2004

Effect of fluvoxamine and erythromycin on the pharmacokinetics of oral lidocaine.

Basic & clinical pharmacology & toxicology, 2006, Volume: 99, Issue:2

Topics: Administration, Oral; Adult; Anesthetics, Local; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Erythromycin; Female; Fluvoxamine; Half-Life; Humans; Lidocaine; Male; Metabolic Clearance Rate; Nausea

2006

Other Studies

1 other study(ies) available for monoethylglycinexylidide and fluvoxamine

Article	Year
Fluvoxamine is a more potent inhibitor of lidocaine metabolism than ketoconazole and erythromycin in vitro. Pharmacology & toxicology, 1999, Volume: 85, Issue:5 Topics: Anesthetics, Local; Autopsy; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythromycin; Fluvoxamine; Humans; In Vitro Techniques; Ketoconazole; Lidocaine; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases	1999

Article

Year

Fluvoxamine is a more potent inhibitor of lidocaine metabolism than ketoconazole and erythromycin in vitro.

Pharmacology & toxicology, 1999, Volume: 85, Issue:5

Topics: Anesthetics, Local; Autopsy; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythromycin; Fluvoxamine; Humans; In Vitro Techniques; Ketoconazole; Lidocaine; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases

1999