Page last updated: 2024-09-04

monodesmethylcitalopram and citalopram

monodesmethylcitalopram has been researched along with citalopram in 49 studies

Compound Research Comparison

Studies (monodesmethylcitalopram)	Trials (monodesmethylcitalopram)	Recent Studies (post-2010) (monodesmethylcitalopram)	Studies (citalopram)	Trials (citalopram)	Recent Studies (post-2010) (citalopram)
50	5	19	5,348	1,424	2,350

Protein Interaction Comparison

Protein	Taxonomy	citalopram (IC50)
5-hydroxytryptamine receptor 4	Cavia porcellus (domestic guinea pig)	0.297
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	2.196
Aromatase	Rattus norvegicus (Norway rat)	0.0018
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	2.196
Alpha-1D adrenergic receptor	Homo sapiens (human)	3.289
5-hydroxytryptamine receptor 2C	Homo sapiens (human)	0.297
Sodium-dependent serotonin transporter	Homo sapiens (human)	0.0227
Sodium-dependent serotonin transporter	Rattus norvegicus (Norway rat)	0.0027
Histamine H1 receptor	Homo sapiens (human)	3.194
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	1.839
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	3.1869
Sigma non-opioid intracellular receptor 1	Homo sapiens (human)	0.398
Transporter	Rattus norvegicus (Norway rat)	8.8

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (6.12)	18.7374
1990's	7 (14.29)	18.2507
2000's	18 (36.73)	29.6817
2010's	19 (38.78)	24.3611
2020's	2 (4.08)	2.80

Authors

Authors	Studies
Andersen, J; Bang-Andersen, B; Eildal, JN; Jørgensen, AM; Jørgensen, M; Kristensen, AS; Strømgaard, K	1
Durand, A; Jørgensen, A; Rop, PP; Viala, A	1
Bouchacourt, M; Dufour, H; Durand, A; Gouezo, F; Høpfner Petersen, HE; Phak Rop, P; Thermoz, P; Viala, A	1
Christensen, P	1
Górka, Z; Mazela, H; Nowak, G; Pawlowski, L	1
Amey, M; Baumann, P; Rochat, B	1
Linnet, K; Olesen, OV	1
Bertelsen, A; Jensen, PN; Linnet, K; Olesen, OV	1
Grollier, G; Larsen, F; Poulsen, M; Priskorn, M; Segonzac, A; Sidhu, J	1
Akerman, KK; Huttunen, H; Jolkkonen, J; Penttilä, I	1
Madea, B; Musshoff, F; Schmidt, P	1
Halvorsen, TG; Pedersen-Bjergaard, S; Rasmussen, KE	1
Ahlner, J; Bengtsson, F; Carlsson, B; Dahl, ML; Lundmark, J; Olsson, G; Reis, M; Wålinder, J	1
Ekblad, U; Heikkine, T; Laine, K	1
Bengtsson, F; Lundmark, J; Reis, M	1
Fanali, S; Mandrioli, R; Pucci, V; Raggi, MA	1
Bertilsson, L; Gustafsson, LL; Herrlin, K; Tybring, G; Widén, J; Yasui-Furukori, N	1
Andersen, S; Halvorsen, TG; Pedersen-Bjergaard, S; Rasmussen, KE; Refsum, H; Tanum, L	1
Gauthier, D; Meng, QH	1
Lambert, WE; Maudens, KE; Van Peteghem, CH; Wille, SM	1
Alkass, K; Carlsson, B; Druid, H; Kingbäck, M; Kugelberg, FC	1
Cheung, Y; Chiu, HF; Chow, MS; Lam, SL; Wang, ZJ; Wing, YK; Yin, OQ	1
Coelho, EB; Lanchote, VL; Marques, MP; Rocha, A	1
Bylund, DB; Deupree, JD; Montgomery, MD	1
Barrio, RJ; Goicolea, MA; Gómez-Caballero, A; Millán, S; Sallés, J; Sampedro, MC; Sánchez, A; Unceta, N	1
Blood, J; Pekary, AE; Sattin, A	1
Burgoyne, KS; Cook, IA; Fava, M; Gilmer, WS; Greenwald, S; Howland, RH; Iosifescu, D; Jain, R; Leuchter, AF; Marangell, LB; McCracken, JT; Trivedi, MH; Zisook, S	1
Hermann, M; Molden, E; Refsum, H; Reubsaet, JL; Rudberg, I	1
Baumer, C; Koren, G; O'Brien, L; Sachs, H; Thieme, D	1
Chen, B; Chen, C; Chen, H; Jiang, T; Lu, Y; Peng, L; Rong, Z; Sun, J; Xie, Y; Xu, Y	1
Ahlner, J; Bengtsson, F; Carlsson, B; Kingbäck, M; Kugelberg, FC	1
Aitchison, KJ; Campbell, D; Craig, IW; Farmer, AE; Giovannini, C; Gray, J; Gunasinghe, C; Hauser, J; Huezo-Diaz, P; Ingelman-Sundberg, M; Maier, W; Marusic, A; McGuffin, P; Mendlewicz, J; Mors, O; Perez, J; Perroud, N; Rietschel, M; Sim, S; Smith, R; Spencer, EP; Uher, R; Virding, S	1
Dean, D; Desrosiers, NA; Watterson, JH; Wyman, JF	1
Florek, E; Jawien, W; Kulza, M; Majcherczyk, J; Piekoszewski, W; Senczuk-Przybylowska, M	1
Bonati, M; Butera, R; Cotti Cottini, F; Eleftheriou, G; Farina, M	1
Barrio, RJ; Díaz, G; García, D; Goicolea, MA; Gómez-Caballero, A; Guerreiro, A; Piletsky, S; Unceta, N	1
Groppi, A; Morini, L; Tricomi, P; Vignali, C	1
Baskak, B; Devrimci Ozguven, H; Ozdemir, H; Ozel-Kizil, ET; Suzen, HS; Uckun, Z	1
Bender, DM; Bies, RR; Eastwood, B; Jackson, K; Lowe, S; Swanson, S; Velez de Mendizabal, N	1
Akil, A; Avramopoulos, D; Bies, RR; Devanand, DP; Lyketsos, CG; Mintzer, JE; Pollock, BG; Porsteinsson, AP; Schneider, LS; Shade, DM; Weintraub, D; Yesavage, J	1
Gründer, G; Hiemke, C; Lammertz, SE; Paulzen, M; Tauber, SC; Veselinovic, T	1
Inoue, Y; Ishioka, M; Kubo, K; Nakamura, K; Tsuchimine, S; Yasui-Furukori, N	1
Ansermot, N; Csajka, C; Eap, CB; Grosjean, D; Hascoët, JM; Nguyen, KA; Panchaud, A; Weisskopf, E	1
Brose, SA; Golovko, MY; Henry, LK; Krout, D; Rodriquez, M; Thompson, BJ	1
Johansen, SS	1
Inoue, Y; Ochi, S; Sugawara, N; Suzuki, Y; Tajiri, M; Tsuchimine, S; Yasui-Furukori, N	1
El Sherbiny, D; Wahba, MEK	1
Dinis-Oliveira, RJ; Durão, C; Pedrosa, F	1
Cecil, K; DelBello, MP; Desta, Z; Mills, JA; Mossman, SA; Poweleit, EA; Ramsey, LB; Schroeder, H; Strawn, JR; Varney, ST	1

Trials

5 trial(s) available for monodesmethylcitalopram and citalopram

Article	Year
Citalopram--a highly selective 5-HT uptake inhibitor--in the treatment of depressed patients. International clinical psychopharmacology, 1987, Volume: 2, Issue:3 Topics: Adult; Aged; Anxiety; Citalopram; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Male; Middle Aged; Propylamines	1987
Serum levels of citalopram and its main metabolites in adolescent patients treated in a naturalistic clinical setting. Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:4 Topics: Adolescent; Citalopram; Confidence Intervals; Contraceptives, Oral; Depressive Disorder, Major; Dose-Response Relationship, Drug; Female; Humans; Male; Prospective Studies; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Sex Factors; Smoking	2002
CYP2C19 genotype predicts steady state escitalopram concentration in GENDEP. Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:3 Topics: Adult; Aged; Antidepressive Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Citalopram; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Female; Genetic Association Studies; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic; Selective Serotonin Reuptake Inhibitors; White People; Young Adult	2012
Measuring citalopram in blood and cerebrospinal fluid: revealing a distribution pattern that differs from other antidepressants. International clinical psychopharmacology, 2016, Volume: 31, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Citalopram; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged	2016
Escitalopram in Adolescents With Generalized Anxiety Disorder: A Double-Blind, Randomized, Placebo-Controlled Study. The Journal of clinical psychiatry, 2020, 08-25, Volume: 81, Issue:5 Topics: Adolescent; Anti-Anxiety Agents; Anxiety Disorders; Area Under Curve; Child; Citalopram; Cytochrome P-450 CYP2C19; Double-Blind Method; Female; Humans; Male; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Treatment Outcome	2020

Other Studies

44 other study(ies) available for monodesmethylcitalopram and citalopram

Article	Year
From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: synthesis and structure-activity relationship studies. Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10 Topics: Animals; Benzofurans; Blood Platelets; Brain; Cell Line; Citalopram; Humans; In Vitro Techniques; Norepinephrine Plasma Membrane Transport Proteins; Propylamines; Rats; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Synaptosomes	2008
Simultaneous determination of citalopram, monodesmethylcitalopram and didesmethylcitalopram in plasma by high-performance liquid chromatography after column extraction. Journal of chromatography, 1990, Apr-27, Volume: 527, Issue:1 Topics: Chromatography, High Pressure Liquid; Citalopram; Humans	1990
Receptor assay based on 3H-imipramine binding. Psychopharmacology series, 1987, Volume: 3 Topics: Antidepressive Agents; Binding, Competitive; Blood Platelets; Chromatography, Thin Layer; Citalopram; Clomipramine; Humans; Imipramine; Propylamines; Radioligand Assay	1987
Ro 11-2465 (cyan-imipramine), citalopram and their N-desmethyl metabolites: effects on the uptake of 5-hydroxytryptamine and noradrenaline in vivo and related pharmacological activities. Psychopharmacology, 1985, Volume: 86, Issue:1-2 Topics: Animals; Antidepressive Agents; Brain; Citalopram; Drug Interactions; Imipramine; Male; Mice; Norepinephrine; Propylamines; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Thyrotropin-Releasing Hormone; Tyramine	1985
Analysis of enantiomers of citalopram and its demethylated metabolites in plasma of depressive patients using chiral reverse-phase liquid chromatography. Therapeutic drug monitoring, 1995, Volume: 17, Issue:3 Topics: Adult; Aged; Chromatography, High Pressure Liquid; Citalopram; Depression; Female; Humans; Male; Middle Aged; Stereoisomerism	1995
Simplified high-performance liquid chromatographic method for the determination of citalopram and desmethylcitalopram in serum without interference from commonly used psychotropic drugs and their metabolites. Journal of chromatography. B, Biomedical applications, 1996, Jan-12, Volume: 675, Issue:1 Topics: Artifacts; Chromatography, High Pressure Liquid; Citalopram; Humans; Psychotropic Drugs; Reference Standards; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Spectrophotometry, Ultraviolet	1996
Citalopram and desmethylcitalopram concentrations in breast milk and in serum of mother and infant. Therapeutic drug monitoring, 1997, Volume: 19, Issue:2 Topics: Adult; Citalopram; Female; Humans; Milk, Human	1997
Steady-state pharmacokinetics of the enantiomers of citalopram and its metabolites in humans. Chirality, 1997, Volume: 9, Issue:7 Topics: Adult; Antidepressive Agents; Biotransformation; Chromatography, High Pressure Liquid; Citalopram; Female; Humans; Male; Stereoisomerism	1997
High-performance liquid chromatography method for analyzing citalopram and desmethylcitalopram from human serum. Therapeutic drug monitoring, 1998, Volume: 20, Issue:1 Topics: Chromatography, High Pressure Liquid; Citalopram; Drug Monitoring; Humans; Selective Serotonin Reuptake Inhibitors	1998
Fatality caused by a combined trimipramine-citalopram intoxication. Forensic science international, 1999, Dec-06, Volume: 106, Issue:2 Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Depression; Drug Overdose; Drug Synergism; Fatal Outcome; Female; Humans; Hypnotics and Sedatives; Liver; Middle Aged; Pyridines; Suicide; Trimipramine; Zolpidem	1999
Liquid-phase microextraction and capillary electrophoresis of citalopram, an antidepressant drug. Journal of chromatography. A, 2001, Feb-09, Volume: 909, Issue:1 Topics: Antidepressive Agents, Second-Generation; Chemistry Techniques, Analytical; Citalopram; Electrophoresis, Capillary; Humans; Polypropylenes; Quality Control; Reproducibility of Results	2001
Transplacental transfer of citalopram, fluoxetine and their primary demethylated metabolites in isolated perfused human placenta. BJOG : an international journal of obstetrics and gynaecology, 2002, Volume: 109, Issue:9 Topics: Citalopram; Female; Fluoxetine; Humans; Maternal-Fetal Exchange; Placenta; Pregnancy; Prospective Studies; Protein Binding; Selective Serotonin Reuptake Inhibitors	2002
Therapeutic drug monitoring of racemic citalopram: a 5-year experience in Sweden, 1992-1997. Therapeutic drug monitoring, 2003, Volume: 25, Issue:2 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Body Mass Index; Child; Chromatography, High Pressure Liquid; Citalopram; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sex Factors; Smoking; Stereoisomerism	2003
Enantiomeric separation of citalopram and its metabolites by capillary electrophoresis. Electrophoresis, 2003, Volume: 24, Issue:15 Topics: beta-Cyclodextrins; Biotransformation; Citalopram; Cyclodextrins; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Stereoisomerism; Temperature	2003
Metabolism of citalopram enantiomers in CYP2C19/CYP2D6 phenotyped panels of healthy Swedes. British journal of clinical pharmacology, 2003, Volume: 56, Issue:4 Topics: Adult; Antidepressive Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Citalopram; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Female; Genotype; Humans; Isomerism; Male; Mixed Function Oxygenases; Phenotype	2003
Stereospecific determination of citalopram and desmethylcitalopram by capillary electrophoresis and liquid-phase microextraction. Journal of pharmaceutical and biomedical analysis, 2003, Sep-19, Volume: 33, Issue:2 Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Citalopram; Depression; Electrophoresis, Capillary; Humans; Middle Aged; Reference Standards; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Stereoisomerism	2003
Simultaneous analysis of citalopram and desmethylcitalopram by liquid chromatography with fluorescence detection after solid-phase extraction. Clinical biochemistry, 2005, Volume: 38, Issue:3 Topics: Chromatography, High Pressure Liquid; Citalopram; Fluorescence; Humans; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity	2005
Development of a solid phase extraction for 13 'new' generation antidepressants and their active metabolites for gas chromatographic-mass spectrometric analysis. Journal of chromatography. A, 2005, Dec-09, Volume: 1098, Issue:1-2 Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Desvenlafaxine Succinate; Fluoxetine; Gas Chromatography-Mass Spectrometry; Humans; Mianserin; Microchemistry; Mirtazapine; Piperazines; Reproducibility of Results; Sertraline	2005
Influence of blood loss on the pharmacokinetics of citalopram. Forensic science international, 2006, Sep-12, Volume: 161, Issue:2-3 Topics: Animals; Blood Chemical Analysis; Brain Chemistry; Chromatography, High Pressure Liquid; Citalopram; Drug Administration Schedule; Female; Forensic Medicine; Hemorrhage; Lung; Models, Animal; Postmortem Changes; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Wounds and Injuries	2006
Phenotype-genotype relationship and clinical effects of citalopram in Chinese patients. Journal of clinical psychopharmacology, 2006, Volume: 26, Issue:4 Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Antidepressive Agents; Aryl Hydrocarbon Hydroxylases; Asian People; China; Citalopram; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Female; Gene Frequency; Genotype; Humans; Male; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Mood Disorders; Phenotype; Polymorphism, Genetic	2006
Enantioselective analysis of citalopram and demethylcitalopram in human and rat plasma by chiral LC-MS/MS: application to pharmacokinetics. Chirality, 2007, Volume: 19, Issue:10 Topics: Animals; Blood Chemical Analysis; Chromatography, Liquid; Citalopram; Humans; Male; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Stereoisomerism; Tandem Mass Spectrometry	2007
Pharmacological properties of the active metabolites of the antidepressants desipramine and citalopram. European journal of pharmacology, 2007, Dec-08, Volume: 576, Issue:1-3 Topics: Animals; Antidepressive Agents; Citalopram; Desipramine; Imipramine; Male; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Serotonin Plasma Membrane Transport Proteins	2007
Simultaneous determination of citalopram, fluoxetine and their main metabolites in human urine samples by solid-phase microextraction coupled with high-performance liquid chromatography. Journal of pharmaceutical and biomedical analysis, 2008, Mar-13, Volume: 46, Issue:4 Topics: Chromatography, High Pressure Liquid; Citalopram; Fluoxetine; Humans; Hydrogen-Ion Concentration; Osmolar Concentration; Solid Phase Extraction; Temperature	2008
Escitalopram regulates expression of TRH and TRH-like peptides in rat brain and peripheral tissues. Neuroendocrinology, 2008, Volume: 88, Issue:2 Topics: Animals; Brain; Citalopram; Corticosterone; Dissection; Epididymis; Male; Organ Size; Peptide Fragments; Prostate; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Testis; Thyrotropin-Releasing Hormone; Time Factors; Tissue Distribution; Tissue Extracts	2008
Comparative effectiveness of biomarkers and clinical indicators for predicting outcomes of SSRI treatment in Major Depressive Disorder: results of the BRITE-MD study. Psychiatry research, 2009, Sep-30, Volume: 169, Issue:2 Topics: Adolescent; Adult; Aged; Biomarkers; Citalopram; Depressive Disorder, Major; Electroencephalography; Female; Frontal Lobe; Humans; Male; Middle Aged; Predictive Value of Tests; Psychiatric Status Rating Scales; Receptors, Serotonin; ROC Curve; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Time Factors; Treatment Outcome; Young Adult	2009
Identification of a novel CYP2C19-mediated metabolic pathway of S-citalopram in vitro. Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:12 Topics: Adult; Antidepressive Agents, Second-Generation; Aryl Hydrocarbon Hydroxylases; Biotransformation; Citalopram; Cytochrome P-450 CYP2C19; Dealkylation; Female; Genotype; Humans; Kinetics; Male; Microsomes; Middle Aged; Models, Biological; Phenotype; Propionates; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors	2009
Changes in antidepressant metabolism in pregnancy evidenced by metabolic ratios in hair: a novel approach. Forensic science international, 2010, Mar-20, Volume: 196, Issue:1-3 Topics: Adult; Antidepressive Agents; Citalopram; Cyclohexanols; Female; Fluoxetine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Postpartum Period; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Third; Sertraline; Venlafaxine Hydrochloride	2010
Simultaneous determination of citalopram and its metabolite in human plasma by LC-MS/MS applied to pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Feb-15, Volume: 878, Issue:5-6 Topics: Chromatography, Liquid; Citalopram; Humans; Sensitivity and Specificity; Tandem Mass Spectrometry	2010
Cytochrome P450-dependent disposition of the enantiomers of citalopram and its metabolites: in vivo studies in Sprague-Dawley and Dark Agouti rats. Chirality, 2011, Volume: 23, Issue:2 Topics: Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Citalopram; Cytochrome P-450 CYP2D6; Female; Humans; Infusion Pumps, Implantable; Mesencephalon; Models, Animal; Phenotype; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Species Specificity; Stereoisomerism	2011
Detection of amitriptyline, citalopram, and metabolites in porcine bones following extended outdoor decomposition. Journal of forensic sciences, 2012, Volume: 57, Issue:2 Topics: Amitriptyline; Animals; Antidepressive Agents; Bone and Bones; Chromatography, Liquid; Citalopram; Environment; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Nortriptyline; Postmortem Changes; Solid Phase Extraction; Swine	2012
Influence of tobacco smoke on the pharmacokinetics of citalopram and its enantiomers. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2012, Volume: 63, Issue:1 Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Citalopram; Half-Life; Limit of Detection; Male; Rats; Rats, Wistar; Stereoisomerism; Tobacco Smoke Pollution	2012
Neonatal toxicity following maternal citalopram treatment. Fetal and pediatric pathology, 2013, Volume: 32, Issue:5 Topics: Citalopram; Depressive Disorder, Major; Diagnosis, Differential; Female; Half-Life; Humans; Infant, Newborn; Male; Neonatal Abstinence Syndrome; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors	2013
Enantioselective extraction of (+)-(S)-citalopram and its main metabolites using a tailor-made stir bar chiral imprinted polymer for their LC-ESI-MS/MS quantitation in urine samples. Talanta, 2013, Nov-15, Volume: 116 Topics: Adsorption; Antidepressive Agents, Second-Generation; Chromatography, Liquid; Citalopram; Humans; Molecular Imprinting; Polymers; Reference Standards; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry	2013
Analytical Challenge in Postmortem Toxicology Applied to a Human Body Found into a Lake after Three Years Immersion. Journal of forensic sciences, 2015, Volume: 60, Issue:5 Topics: Adult; Antipsychotic Agents; Bile; Brain Chemistry; Chromatography, Liquid; Citalopram; Dibenzothiazepines; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Glucuronates; Hair; Humans; Immersion; Kidney; Lakes; Lung; Muscle, Skeletal; Postmortem Changes; Time Factors	2015
The impact of CYP2C19 polymorphisms on citalopram metabolism in patients with major depressive disorder. Journal of clinical pharmacy and therapeutics, 2015, Volume: 40, Issue:6 Topics: Adult; Aged; Citalopram; Cytochrome P-450 CYP2C19; Depressive Disorder, Major; Dose-Response Relationship, Drug; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Polymorphism, Genetic	2015
A population PK model for citalopram and its major metabolite, N-desmethyl citalopram, in rats. Journal of pharmacokinetics and pharmacodynamics, 2015, Volume: 42, Issue:6 Topics: Administration, Intravenous; Administration, Oral; Animals; Antidepressive Agents, Second-Generation; Area Under Curve; Biological Availability; Biotransformation; Citalopram; Computer Simulation; Linear Models; Male; Metabolic Clearance Rate; Models, Animal; Models, Biological; Models, Statistical; Monte Carlo Method; Nonlinear Dynamics; Rats, Sprague-Dawley; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Species Specificity	2015
A population pharmacokinetic model for R- and S-citalopram and desmethylcitalopram in Alzheimer's disease patients with agitation. Journal of pharmacokinetics and pharmacodynamics, 2016, Volume: 43, Issue:1 Topics: Aged; Aged, 80 and over; Aging; Algorithms; Alzheimer Disease; Antidepressive Agents; Citalopram; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Nonlinear Dynamics; Psychomotor Agitation; Sex Characteristics; Stereoisomerism; Structure-Activity Relationship	2016
The Effects of Fluvoxamine on the Steady-State Plasma Concentrations of Escitalopram and Desmethylescitalopram in Depressed Japanese Patients. Therapeutic drug monitoring, 2016, Volume: 38, Issue:4 Topics: Asian People; Citalopram; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Depression; Female; Fluvoxamine; Genotype; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors	2016
Stereoselective determination of citalopram and desmethylcitalopram in human plasma and breast milk by liquid chromatography tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2016, Nov-30, Volume: 131 Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Citalopram; Humans; Milk, Human; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry	2016
Inhibition of the Serotonin Transporter Is Altered by Metabolites of Selective Serotonin and Norepinephrine Reuptake Inhibitors and Represents a Caution to Acute or Chronic Treatment Paradigms. ACS chemical neuroscience, 2017, 05-17, Volume: 8, Issue:5 Topics: Animals; Citalopram; Fluoxetine; Mice; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Sertraline; Synaptosomes	2017
Enantioselective analysis of citalopram and demethylcitalopram in human whole blood by chiral LC-MS/MS and application in forensic cases. Drug testing and analysis, 2017, Volume: 9, Issue:10 Topics: Antidepressive Agents, Second-Generation; Autopsy; Chromatography, High Pressure Liquid; Citalopram; Forensic Toxicology; Humans; Limit of Detection; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Stereoisomerism; Tandem Mass Spectrometry	2017
Effects of Cytochrome P450 (CYP) 2C19 Genotypes on Steady-State Plasma Concentrations of Escitalopram and its Desmethyl Metabolite in Japanese Patients With Depression. Therapeutic drug monitoring, 2018, Volume: 40, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Citalopram; Cytochrome P-450 CYP2C19; Depression; Female; Genotype; Humans; Japan; Male; Middle Aged; Retrospective Studies; Young Adult	2018
Micellar liquid chromatographic method for the simultaneous determination of citalopram hydrobromide with its two demethylated metabolites. Utility as a diagnostic tool in forensic toxicology. Journal of pharmaceutical and biomedical analysis, 2019, Feb-05, Volume: 164 Topics: Animals; Autopsy; Chemical Fractionation; Chromatography, High Pressure Liquid; Citalopram; Forensic Toxicology; Limit of Detection; Liver; Micelles; Models, Animal; Myocardium; Rats; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets	2019
A fatal case by a suicide kit containing sodium nitrite ordered on the internet. Journal of forensic and legal medicine, 2020, Volume: 73 Topics: Adult; Chromatography, Gas; Chromatography, Liquid; Citalopram; Commerce; Food Preservatives; Gastrointestinal Contents; Humans; Internet; Male; Mass Spectrometry; Nitrites; Sodium Nitrite; Suicide, Completed; Trazodone	2020