Page last updated: 2024-09-03

monobutyryl cyclic amp and 1-methyl-3-isobutylxanthine

monobutyryl cyclic amp has been researched along with 1-methyl-3-isobutylxanthine in 11 studies

Compound Research Comparison

Studies (monobutyryl cyclic amp)	Trials (monobutyryl cyclic amp)	Recent Studies (post-2010) (monobutyryl cyclic amp)	Studies (1-methyl-3-isobutylxanthine)	Trials (1-methyl-3-isobutylxanthine)	Recent Studies (post-2010) (1-methyl-3-isobutylxanthine)
55	0	2	5,148	5	279

Protein Interaction Comparison

Protein	Taxonomy	1-methyl-3-isobutylxanthine (IC50)
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	Homo sapiens (human)	8.1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	31
Chain A, Phosphodiesterase 9A	Homo sapiens (human)	500
Chain A, Class I phosphodiesterase PDEB1	Leishmania major	580
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	Homo sapiens (human)	698
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	40
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	Homo sapiens (human)	117.2
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	Homo sapiens (human)	117.2
Phosphodiesterase	Bos taurus (cattle)	9.9
cGMP-dependent 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	4
cGMP-specific 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	3.1667
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	Bos taurus (cattle)	9.9
Adenosine receptor A1	Rattus norvegicus (Norway rat)	7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	Homo sapiens (human)	3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	Bos taurus (cattle)	9.9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	Homo sapiens (human)	3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	Rattus norvegicus (Norway rat)	0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	Homo sapiens (human)	0.242
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	Homo sapiens (human)	3.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Homo sapiens (human)	7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	Rattus norvegicus (Norway rat)	0.1
Phosphodiesterase	Rattus norvegicus (Norway rat)	0.1

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (63.64)	18.7374
1990's	4 (36.36)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Björntorp, P; De Pergola, G; Giorgino, R; Holmäng, A; Svedberg, J	1
Mangiarua, EI; McCumbee, WD	1
Bartholdi, M; Haag, M; Johnson, R; Krystosek, A; Puck, TT	1
Bonini, NM; Gustin, MC; Nelson, DL	1
Lönnroth, P; Smith, U	1
Butler, RD; Evans, RL; McCrohan, CR	1
Bicknell, RJ; Schofield, JG	1
Burch, WM; Lebovitz, HE	2
Bomboy, JD; Salmon, WD; Sullivan, JN	1
Telfer, WH; Wang, Y	1

Other Studies

11 other study(ies) available for monobutyryl cyclic amp and 1-methyl-3-isobutylxanthine

Article	Year
Testosterone treatment of ovariectomized rats: effects on lipolysis regulation in adipocytes. Acta endocrinologica, 1990, Volume: 123, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Bucladesine; Colforsin; Cyclic AMP; Epinephrine; Female; Isoproterenol; Lipolysis; Norepinephrine; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Testosterone	1990
Effects of cyclic adenosine 3',5'-monophosphate on amino acid transport and incorporation into protein in the rat aorta. Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:7 Topics: 1-Methyl-3-isobutylxanthine; Amino Acids; Aminoisobutyric Acids; Animals; Aorta, Thoracic; Bucladesine; Cyclic AMP; Extracellular Space; In Vitro Techniques; Male; Muscle Proteins; Rats; Rats, Inbred Strains	1991
Confocal microscopy of genome exposure in normal, cancer, and reverse-transformed cells. Somatic cell and molecular genetics, 1991, Volume: 17, Issue:5 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cell Nucleolus; Cell Nucleus; Cell Transformation, Neoplastic; CHO Cells; Cricetinae; Deoxyribonuclease I; DNA; DNA, Neoplasm; Fibroblasts; Genome; Microscopy, Fluorescence; Phenotype; Tumor Cells, Cultured	1991
Regulation of ciliary motility by membrane potential in Paramecium: a role for cyclic AMP. Cell motility and the cytoskeleton, 1986, Volume: 6, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Bucladesine; Cell Membrane; Cell Movement; Cilia; Cyclic AMP; Homeostasis; Membrane Potentials; Paramecium; Potassium	1986
The antilipolytic effect of insulin in human adipocytes requires activation of the phosphodiesterase. Biochemical and biophysical research communications, 1986, Dec-30, Volume: 141, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Deaminase; Adipose Tissue; Bucladesine; Enzyme Activation; Humans; Insulin; Isoproterenol; Lipolysis; Phenylisopropyladenosine	1986
Tentacle contraction in Heliophrya erhardi (Suctoria): the role of inositol phospholipid metabolites and cyclic nucleotides in stimulus-response coupling. Experimental cell research, 1988, Volume: 177, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Chlorides; Ciliophora; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Inositol Phosphates; Lithium; Lithium Chloride; Muscle Contraction; Pyrimidinones; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thiazoles	1988
Role of cyclic nucleotides in the inhibition of growth-hormone secretion by somatostatin. Molecular and cellular endocrinology, 1981, Volume: 22, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cattle; Cholera Toxin; Cyclic AMP; Cyclic GMP; Female; Growth Hormone; Male; Pituitary Gland, Anterior; Somatostatin	1981
Adenosine 3',5'-monophosphate: a modulator of embryonic chick cartilage growth. The Journal of clinical investigation, 1981, Volume: 68, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cartilage; Chick Embryo; Culture Media; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Growth Substances; Organ Culture Techniques; Organ Size; Pelvic Bones; Time Factors	1981
In vitro stimulation of alkaline phosphatase activity in immature embryonic chick pelvic cartilage by adenosine 3'5'-monophosphate. The Journal of cell biology, 1982, Volume: 93, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Animals; Bucladesine; Cartilage; Chick Embryo; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Organ Culture Techniques; Stimulation, Chemical; Time Factors	1982
Stimulation of uridine, leucine, and sulfate incorporation into rat cartilage macromolecules by adenosine 3',5'-monophosphate. Endocrinology, 1984, Volume: 115, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; Adenosine Monophosphate; Animals; Bucladesine; Cartilage; Hypophysectomy; In Vitro Techniques; Leucine; Macromolecular Substances; Male; Nucleotides, Cyclic; Parathyroid Hormone; Rats; Rats, Inbred Strains; Ribs; Stimulation, Chemical; Sulfates; Uridine	1984
Cyclic nucleotide-induced termination of vitellogenin uptake by Hyalophora cecropia follicles. Insect biochemistry and molecular biology, 1996, Volume: 26, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Drug Synergism; Enzyme Activation; Female; Isoquinolines; Moths; Nucleotides, Cyclic; Oviducts; Phosphodiesterase Inhibitors; Sulfonamides; Vitellogenins	1996