Page last updated: 2024-08-18

monobutyl phthalate and dibutyl phthalate

monobutyl phthalate has been researched along with dibutyl phthalate in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.03)18.7374
1990's3 (4.55)18.2507
2000's19 (28.79)29.6817
2010's26 (39.39)24.3611
2020's16 (24.24)2.80

Authors

AuthorsStudies
Higuti, T; Murakami, K; Nishiyama, K1
Melnick, RL; Schiller, CM1
Fukuoka, M; Hayakawa, T; Kobayashi, T1
Fukuoka, M; Hayakawa, T; Kobayashi, T; Niimi, S; Zhou, Y1
Coldham, NG; Dave, M; Sauer, MJ1
Conolly, RB; Kepler, TB; Keys, DA; Wallace, DG1
Langonné, I; Leheup, B; Saillenfait, AM1
Anderson, WA; Castle, L; Massey, RC; Scotter, MJ; Springall, C1
Choi, YW; Han, SY; Kim, SH; Kim, SS; Kwack, SJ; Kwon, O; Lee, MK; Park, KL; Sohn, KH1
Ema, M1
Gaido, KW; Ross, SM; Thompson, CJ1
Borghoff, SJ; Kremer, JJ; Parkinson, HD; Williams, CC1
Barr, DB; Brock, JW; Calafat, AM; Gray, LE; Needham, LL; Reidy, JA; Silva, MJ1
Karegoudar, TB; Kundapur, R; Patil, NK; Shouche, YS1
Calafat, AM; Green, RA; Hauser, R; Hu, H; Sánchez, BN; Schettler, T; Weuve, J1
Hanaoka, T; Inoue, K; Nakazawa, H; Pan, G; Takahashi, K; Tsugane, S; Tsukino, H; Wang, P; Yoshimura, M; Zhang, S1
Anderson, RA; Bayne, R; Coutts, S; Greig, I; Hallmark, N; Mahood, IK; McKinnell, C; Morris, K; Scott, H; Sharpe, RM; Walker, M1
Andersen, ME; Borghoff, SJ; Campbell, JL; Clewell, RA; Kremer, JJ; Williams, CC1
Sharpe, RM1
Han, SY; Im, JY; Jung, KK; Kim, HJ; Kim, HS; Kim, J; Kim, SH; Lee, BM; Lee, E; Lee, J; Park, H; Ryu, JY; Shim, KA1
Andersen, ME; Borghoff, SJ; Campbell, JL; Clewell, RA; Kremer, JJ; Sochaski, MA; Williams, CC1
Divya, LM; Prasanth, GK; Sadasivan, C1
Fromme, H; Seckin, E; Völkel, W1
Dorman, DC; Gaido, KW; Hensley, JB; Lehmann, KP; Ross, SM; Sochaski, MA; Struve, MF; Willson, GA1
Hines, M; Kruse, RL; Liu, F; Redmon, JB; Sparks, A; Swan, SH; Wang, C; Weiss, B1
Guo, Y; Kannan, K; Wu, Q1
Du, G; Han, X; Hu, W; Jiang, Y; Liu, R; Shen, O; Shi, W; Song, L; Sun, H; Wang, S; Wang, X; Wu, W; Xia, Y; Yu, L1
Chen, X; Leng, L; Tang, NJ; Zhang, JS; Zhou, QH1
Chen, X; Leng, L; Sun, ZR; Tang, NJ; Zhou, QH1
Bae, S; Hong, YC; Kim, JH; Lim, YH; Park, HY1
C H, R; Misra, S; Ram, KR; Reddy Mudiam, MK; Sharma, V; Singh, A1
Chen, Y; Jiang, Q; Wang, B; Wang, H; Zhou, W; Zhou, Y1
Bendtzen, K; Brorson, MM; Feldt-Rasmussen, U; Frederiksen, H; Hansen, JF; Hartoft-Nielsen, ML; Nielsen, CH; Rasmussen, ÅK1
Chen, Y; Cobbina, SJ; Feng, W; Huang, J; Mao, G; Wang, W; Wu, X; Xu, H; Yang, L; Zhang, Z; Zhou, Z1
Dong, C; Hu, Q; Hu, Y; Li, S; Li, Y; Li, Z; Lu, H; Qin, H; Wang, Y; Zhang, C1
Bendtzen, K; Boas, M; Brorson, MM; Feldt-Rasmussen, U; Frederiksen, H; Frisch, T; Hansen, JF; Hartoft-Nielsen, ML; Hofman-Bang, J; Lindström, ES; Main, KM; Nielsen, CH; Rasmussen, ÅK1
Chen, X; Ge, RS; Hu, G; Li, L; Li, X; Lian, QQ; Wang, M; Wang, S; Xu, R; Zhu, Q1
Gu, Y; Hu, X; Huang, W; Yin, D1
Chao, Y; Chen, S; Huang, X; Lin, Q; Qiu, R; Wang, S1
Hatanaka, T; Hosoya, O; Jinno, H; Juni, K; Kobayashi, M; Mashimo, Y; Sugibayashi, K; Sugino, M; Suzuki, T; Todo, H1
Campbell, J; Clewell, H; Isaacs, K; Leonard, J; Moreau, M; Nicolas, C; Pendse, SN; Phillips, KA; Phillips, M; Pudukodu, H; Smith, S; Tan, YM; Yoon, M1
Imai, Y; Kurohane, K; Ogawa, E; Sekiguchi, K; Tsutsumi, M1
Choi, YH; Hong, YC; Kim, KN; Lee, KS; Lee, N; Lim, YH1
Chang, JW; Chiang, HC; Huang, HB; Huang, PC; Kuo, PL; Liao, KW1
Chen, B; Hu, GX; Hu, X; Zhen, X1
Capanna, S; Caporossi, L; Paci, E; Papaleo, B; Pigini, D; Tranfo, G1
Chen, X; Li, P; Luo, T; Sun, X; Weng, S; Xia, T; Xie, F1
Kamiya, Y; Miura, T; Mizuno, S; Murayama, N; Shimizu, M; Suemizu, H; Uehara, S; Yamazaki, H; Yoshizawa, M1
Li, X; Liu, L; Shen, H; Wang, H; Xiao, T; Zhang, X1
Sicińska, P1
Chen, S; Gu, A; Gu, C; Hu, Y; Wang, Y; Wen, Y; Zhang, J; Zhang, L1
Chen, Z; Diogene, T; Han, W; He, Z; Jiao, Y; Tao, Y; Wu, P; Yang, Y; Yu, H; Zhang, Y1
Fernando, RA; Robinson, VG; Silinski, MAR; Waidyanatha, S1
Cun, D; Dai, Y; Fan, Y; Li, T; Liang, W; Song, X; Wang, F; Wu, C1
Gao, Q; Hong, Q; Jiang, W; Lu, M; Zhang, M1
Ding, J; Han, X; Ji, J; Li, D; Ma, T; Wang, Y; Wu, J; Xia, Y; Zhang, L1
Bukowska, B; Kik, K; Sicińska, P1
Chen, Y; Ding, J; Han, X; Hou, J; Li, D; Ma, T; Qiu, J; Wu, J; Zhou, Y1
Akindolie, MS; Jiao, Y; Qu, J; Tao, Y; Wang, L; Wu, S; Yang, Y; Zhang, Y; Zhu, G; Zhu, T1
Bukowska, B; Michałowicz, J; Mokra, K; Sicińska, P; Wozniak, K1
Craig, ZR; Jauregui, EJ; Lock, J; Rasmussen, L1
Ding, J; Han, X; Jin, H; Li, D; Ma, T; Wang, B; Wang, J; Wu, J; Xia, Y; Yang, F; Zhou, Y1
Balcerczyk, A; Bukowska, B; Jabłońska, E; Reszka, E; Sicińska, P1
Källsten, L; Karlsson, O; Martin, JW; Pierozan, P1
Jin, L; Liang, J; Lu, G; Sun, J; Xing, H; Yu, X; Zhu, L; Zhu, M1
Chen, J; Han, X; Hao, L; Li, D; Li, L; Liu, Y; Xia, Y1

Reviews

1 review(s) available for monobutyl phthalate and dibutyl phthalate

ArticleYear
Antiandrogenic effects of dibutyl phthalate and its metabolite, monobutyl phthalate, in rats.
    Congenital anomalies, 2002, Volume: 42, Issue:4

    Topics: Androgen Antagonists; Animals; Dibutyl Phthalate; Female; Phthalic Acids; Pregnancy; Rats; Rats, Wistar

2002

Trials

2 trial(s) available for monobutyl phthalate and dibutyl phthalate

ArticleYear
A biomarker approach to measuring human dietary exposure to certain phthalate diesters.
    Food additives and contaminants, 2001, Volume: 18, Issue:12

    Topics: Biomarkers; Carbon Isotopes; Chromatography, Liquid; Dibutyl Phthalate; Diethylhexyl Phthalate; Esters; Food Contamination; Humans; Mass Spectrometry; Metabolic Clearance Rate; Phthalic Acids

2001
Determination of total and free mono-n-butyl phthalate in human urine samples after medication of a di-n-butyl phthalate containing capsule.
    Toxicology letters, 2009, Jul-10, Volume: 188, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Biotransformation; Capsules; Child; Dibutyl Phthalate; Female; Glucuronidase; Glucuronides; Humans; Male; Maximum Tolerated Dose; Middle Aged; Phthalic Acids; Plasticizers; Risk Assessment

2009

Other Studies

63 other study(ies) available for monobutyl phthalate and dibutyl phthalate

ArticleYear
Toxicity of dibutyl phthalate and its metabolites in rats.
    Nihon eiseigaku zasshi. Japanese journal of hygiene, 1986, Volume: 41, Issue:4

    Topics: Animals; Dibutyl Phthalate; Diethylhexyl Phthalate; Esters; Liver; Male; Phthalic Acids; Rats; Rats, Inbred Strains

1986
Effect of phthalate esters on energy coupling and succinate oxidation in rat liver mitochondria.
    Toxicology, 1985, Volume: 34, Issue:1

    Topics: Animals; Dibutyl Phthalate; Diethylhexyl Phthalate; Energy Metabolism; In Vitro Techniques; Male; Mitochondria, Liver; Mitochondrial Swelling; Oxidative Phosphorylation; Phthalic Acids; Potassium; Rats; Succinate Dehydrogenase; Succinates; Valinomycin

1985
Mechanism of testicular atrophy induced by Di-n-butyl phthalate in rats. VI. A possible origin of testicular iron depletion.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:12

    Topics: Animals; Atrophy; Dibutyl Phthalate; Erythrocytes; Glutathione; Heinz Bodies; Iron; Male; Phthalic Acids; Rats; Rats, Wistar; Testis

1994
Responsiveness of rat nonparenchymal liver cells and spleen cells to the decomposition of erythrocytes exposed to di-n-butyl phthalate and its metabolite.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:9

    Topics: Animals; Dibutyl Phthalate; Erythrocyte Aging; Erythrocyte Count; Erythrocytes; Hematocrit; Hemoglobins; Hemosiderin; Iron; Liver; Male; Phagocytosis; Phthalic Acids; Rats; Rats, Wistar; Spleen; Transferrin

1996
Analysis of di-n-butylphthalate biotransformation in cattle by liquid chromatography/ion trap mass spectrometry/mass spectrometry.
    Journal of mass spectrometry : JMS, 1998, Volume: 33, Issue:9

    Topics: Animals; Bile; Biotransformation; Cattle; Cells, Cultured; Chromatography, Liquid; Dibutyl Phthalate; Feces; Female; Gas Chromatography-Mass Spectrometry; Glucuronidase; Hydroxylation; Liver; Mass Spectrometry; Phthalic Acids; Sulfatases

1998
Quantitative evaluation of alternative mechanisms of blood disposition of di(n-butyl) phthalate and mono(n-butyl) phthalate in rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 53, Issue:2

    Topics: Administration, Oral; Animals; Dibutyl Phthalate; Environmental Pollutants; Injections, Intravenous; Male; Models, Biological; Phthalic Acids; Rats; Rats, Sprague-Dawley; Rats, Wistar

2000
Effects of mono-n-butyl phthalate on the development of rat embryos: in vivo and in vitro observations.
    Pharmacology & toxicology, 2001, Volume: 89, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Dibutyl Phthalate; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Female; Organ Culture Techniques; Phthalic Acids; Pregnancy; Rats; Rats, Sprague-Dawley

2001
Effects of dibutyl phthalate and monobutyl phthalate on cytotoxicity and differentiation in cultured rat embryonic limb bud cells; protection by antioxidants.
    Journal of toxicology and environmental health. Part A, 2002, Volume: 65, Issue:5-6

    Topics: Animals; Antioxidants; Catalase; Cell Culture Techniques; Cell Differentiation; Dibutyl Phthalate; Extremities; Female; Free Radicals; Lethal Dose 50; Oxidative Stress; Phthalic Acids; Rats; Rats, Wistar; Vitamin E

2002
Di(n-butyl) phthalate impairs cholesterol transport and steroidogenesis in the fetal rat testis through a rapid and reversible mechanism.
    Endocrinology, 2004, Volume: 145, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholesterol; Dibutyl Phthalate; DNA-Binding Proteins; Female; Fushi Tarazu Transcription Factors; Gene Expression; Homeodomain Proteins; Male; Phthalic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Steroidogenic Factor 1; Testis; Testosterone; Transcription Factors; Transcription, Genetic

2004
Pharmacokinetics of monobutylphthalate, the active metabolite of di-n-butylphthalate, in pregnant rats.
    Toxicology letters, 2005, Nov-15, Volume: 159, Issue:2

    Topics: Animals; Chromatography, Liquid; Dibutyl Phthalate; Female; Fetus; Glucuronides; Male; Mass Spectrometry; Maternal-Fetal Exchange; Phthalic Acids; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Teratogens

2005
Urinary and amniotic fluid levels of phthalate monoesters in rats after the oral administration of di(2-ethylhexyl) phthalate and di-n-butyl phthalate.
    Toxicology, 2006, Jan-05, Volume: 217, Issue:1

    Topics: Administration, Oral; Amniotic Fluid; Animals; Creatinine; Dibutyl Phthalate; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Female; Gestational Age; Glucuronides; Male; Phthalic Acids; Pregnancy; Rats; Rats, Sprague-Dawley

2006
Degradation of a Plasticizer, di-n-Butylphthalate by Delftia sp. TBKNP-05.
    Current microbiology, 2006, Volume: 52, Issue:3

    Topics: Biodegradation, Environmental; Biological Transport; Delftia; Dibutyl Phthalate; Hydroxybenzoates; Oxygen; Phthalic Acids; Phylogeny; Plasticizers

2006
Exposure to phthalates in neonatal intensive care unit infants: urinary concentrations of monoesters and oxidative metabolites.
    Environmental health perspectives, 2006, Volume: 114, Issue:9

    Topics: Age Factors; Biomarkers; Child; Child, Preschool; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Exposure; Environmental Monitoring; Humans; Infant; Infant, Newborn; Intensive Care Units, Neonatal; Oxidation-Reduction; Phthalic Acids; Plasticizers; Risk Factors; Sex Factors

2006
Decreased serum free testosterone in workers exposed to high levels of di-n-butyl phthalate (DBP) and di-2-ethylhexyl phthalate (DEHP): a cross-sectional study in China.
    Environmental health perspectives, 2006, Volume: 114, Issue:11

    Topics: Adult; Air Pollutants, Occupational; China; Cross-Sectional Studies; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Monitoring; Estradiol; Floors and Floorcoverings; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Occupational Exposure; Phthalic Acids; Plasticizers; Polyvinyl Chloride; Testosterone

2006
Effects of monobutyl and di(n-butyl) phthalate in vitro on steroidogenesis and Leydig cell aggregation in fetal testis explants from the rat: comparison with effects in vivo in the fetal rat and neonatal marmoset and in vitro in the human.
    Environmental health perspectives, 2007, Volume: 115, Issue:3

    Topics: Animals; Animals, Newborn; Callithrix; Cell Aggregation; Dibutyl Phthalate; Female; Humans; Leydig Cells; Male; Maternal Exposure; Phthalic Acids; Pregnancy; Rats; Rats, Wistar; Testis; Testosterone

2007
Tissue exposures to free and glucuronidated monobutylyphthalate in the pregnant and fetal rat following exposure to di-n-butylphthalate: evaluation with a PBPK model.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 103, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dibutyl Phthalate; Female; Fetus; Glucuronides; Male; Maternal Exposure; Models, Biological; Phthalic Acids; Pregnancy; Rats; Rats, Sprague-Dawley; Tissue Distribution

2008
"Additional" effects of phthalate mixtures on fetal testosterone production.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 105, Issue:1

    Topics: Animals; Cryptorchidism; Dibutyl Phthalate; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Fetus; Humans; Male; Phthalic Acids; Risk Assessment; Testis; Testosterone

2008
Hypothyroidism protects di(n-butyl) phthalate-induced reproductive organs damage in Sprague-Dawley male rats.
    The Journal of toxicological sciences, 2008, Volume: 33, Issue:3

    Topics: Animals; Body Weight; Dibutyl Phthalate; Hypothyroidism; Male; Organ Size; Phthalic Acids; Propylthiouracil; Rats; Rats, Sprague-Dawley; Testis; Thyroid Hormones; Thyrotropin

2008
Kinetics of selected di-n-butyl phthalate metabolites and fetal testosterone following repeated and single administration in pregnant rats.
    Toxicology, 2009, Jan-08, Volume: 255, Issue:1-2

    Topics: Amniotic Fluid; Animals; Area Under Curve; Biomarkers; Calibration; Chromatography, High Pressure Liquid; Dibutyl Phthalate; Dose-Response Relationship, Drug; Female; Fetus; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Liver; Male; Mass Spectrometry; Phthalic Acids; Placenta; Pregnancy; Quality Control; Quinolines; Rats; Rats, Sprague-Dawley; Sexual Maturation; Testis; Testosterone

2009
Effects of mono and di(n-butyl) phthalate on superoxide dismutase.
    Toxicology, 2009, Jul-28, Volume: 262, Issue:1

    Topics: Animals; Binding Sites; Cattle; Dibutyl Phthalate; Dose-Response Relationship, Drug; Humans; Hydrogen Bonding; Hydrogen Peroxide; Lung; Models, Molecular; Phthalic Acids; Plasticizers; Protein Binding; Reactive Oxygen Species; Superoxide Dismutase

2009
Reproductive toxicity and pharmacokinetics of di-n-butyl phthalate (DBP) following dietary exposure of pregnant rats.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2009, Volume: 86, Issue:4

    Topics: Administration, Oral; Amniotic Fluid; Androgen Antagonists; Animals; Biotransformation; Body Weight; Dibutyl Phthalate; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation, Developmental; Genitalia, Male; Gestational Age; Glucuronides; Male; Phthalic Acids; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Scavenger Receptors, Class B; Steroids; Testis; Testosterone

2009
Prenatal phthalate exposure and reduced masculine play in boys.
    International journal of andrology, 2010, Volume: 33, Issue:2

    Topics: Child, Preschool; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Exposure; Female; Gender Identity; Humans; Infant; Male; Maternal Exposure; Phthalic Acids; Play and Playthings; Pregnancy; Prenatal Exposure Delayed Effects; Sex Differentiation

2010
Phthalate metabolites in urine from China, and implications for human exposures.
    Environment international, 2011, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Biomarkers; Child; China; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Exposure; Environmental Pollutants; Female; Food Safety; Humans; Male; Phthalic Acids; Plasticizers; Young Adult

2011
Thyroid disruption by Di-n-butyl phthalate (DBP) and mono-n-butyl phthalate (MBP) in Xenopus laevis.
    PloS one, 2011, Apr-22, Volume: 6, Issue:4

    Topics: Animals; Dibutyl Phthalate; Phthalic Acids; Protein Binding; Receptors, Thyroid Hormone; Retinoid X Receptor gamma; Thyroid Gland; Thyroid Hormone Receptors beta; Thyrotropin; Xenopus laevis

2011
[Effects of dibutyl phthalate and monobutyl phthalate on testosterone secretion and insulin-like factor 3 expression of Leydig tumor cells in mice].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2013, Volume: 31, Issue:2

    Topics: Animals; Cell Line; Dibutyl Phthalate; Insulin; Leydig Cells; Male; Mice; Phthalic Acids; Proteins; Testosterone

2013
Effects of di(n-butyl) and monobutyl phthalate on steroidogenesis pathways in the murine Leydig tumor cell line MLTC-1.
    Environmental toxicology and pharmacology, 2013, Volume: 36, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Cell Line, Tumor; Cell Survival; Cholesterol Side-Chain Cleavage Enzyme; Dibutyl Phthalate; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Insulin; Leydig Cell Tumor; Male; Mice; Phthalic Acids; Proteins; RNA, Messenger; Testicular Neoplasms; Testosterone; Time Factors

2013
Diethylhexyl phthalates is associated with insulin resistance via oxidative stress in the elderly: a panel study.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Aged; Aged, 80 and over; Aging; Blood Glucose; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Pollutants; Fasting; Female; Humans; Insulin; Insulin Resistance; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Phthalic Acids; Regression Analysis; Sex Factors

2013
Identification of Drosophila-based endpoints for the assessment and understanding of xenobiotic-mediated male reproductive adversities.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 141, Issue:1

    Topics: Animals; Dibutyl Phthalate; Drosophila melanogaster; Environmental Pollutants; Fertility; Infertility, Male; Male; Microscopy, Confocal; Phthalic Acids; Reproduction; Sperm Count; Spermatozoa; Transcriptome; Xenobiotics

2014
Urinary excretion of phthalate metabolites in school children of China: implication for cumulative risk assessment of phthalate exposure.
    Environmental science & technology, 2015, Jan-20, Volume: 49, Issue:2

    Topics: Child; China; Creatinine; Dibutyl Phthalate; Environmental Exposure; Environmental Pollutants; Female; Humans; Male; No-Observed-Adverse-Effect Level; Phthalic Acids; Proportional Hazards Models; Quality Control; Risk Assessment

2015
Influence of phthalates on in vitro innate and adaptive immune responses.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Adaptive Immunity; Cytokines; Dibutyl Phthalate; Female; Humans; Immunity, Innate; Lipopolysaccharides; Macrophages; Male; Monocytes; Phthalic Acids; Phytohemagglutinins; T-Lymphocytes

2015
Neurological Toxicity of Individual and Mixtures of Low Dose Arsenic, Mono and Di (n-butyl) Phthalates on Sub-Chronic Exposure to Mice.
    Biological trace element research, 2016, Volume: 170, Issue:1

    Topics: Acetylcholinesterase; Animals; Arsenic; Blotting, Western; Central Nervous System; Dibutyl Phthalate; Dose-Response Relationship, Drug; Lipid Peroxidation; Male; Maze Learning; Mice; Nitric Oxide Synthase; Phthalic Acids; Superoxide Dismutase

2016
Vimentin-Mediated Steroidogenesis Induced by Phthalate Esters: Involvement of DNA Demethylation and Nuclear Factor κB.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Survival; Dibutyl Phthalate; DNA; DNA Methylation; Endocrine Disruptors; Male; Mice; NF-kappa B; Phosphoproteins; Phthalic Acids; Progesterone; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA Interference; Vimentin

2016
Phthalates Are Metabolised by Primary Thyroid Cell Cultures but Have Limited Influence on Selected Thyroid Cell Functions In Vitro.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Cells, Cultured; Cyclic AMP; Dibutyl Phthalate; Diethylhexyl Phthalate; Humans; Phthalic Acids; Plasticizers; Thyroglobulin; Thyroid Gland

2016
Comparison of the Effects of Dibutyl and Monobutyl Phthalates on the Steroidogenesis of Rat Immature Leydig Cells.
    BioMed research international, 2016, Volume: 2016

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Dibutyl Phthalate; Down-Regulation; Endocrine System; Leydig Cells; Male; Phthalic Acids; Rats; Reproduction; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Steroids; Testosterone

2016
Phthalate monoesters as markers of phthalate contamination in wild marine organisms.
    Environmental pollution (Barking, Essex : 1987), 2016, Volume: 218

    Topics: Animals; Aquatic Organisms; China; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Monitoring; Esters; Fishes; Mollusca; Phthalic Acids; Rivers; Water Pollutants, Chemical

2016
Carboxylesterase-involved metabolism of di-n-butyl phthalate in pumpkin (Cucurbita moschata) seedlings.
    Environmental pollution (Barking, Essex : 1987), 2017, Volume: 220, Issue:Pt A

    Topics: Carboxylesterase; Cucurbita; Dibutyl Phthalate; Phthalic Acids; Plant Roots; Seedlings; Soil Pollutants

2017
Safety evaluation of dermal exposure to phthalates: Metabolism-dependent percutaneous absorption.
    Toxicology and applied pharmacology, 2017, 08-01, Volume: 328

    Topics: Animals; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Exposure; Environmental Pollutants; Esterases; Female; Humans; In Vitro Techniques; Male; Middle Aged; Phthalic Acids; Plasticizers; Rats; Rats, Hairless; Risk Assessment; Skin; Skin Absorption; Species Specificity

2017
Using exposure prediction tools to link exposure and dosimetry for risk-based decisions: A case study with phthalates.
    Chemosphere, 2017, Volume: 184

    Topics: Dibutyl Phthalate; Diethylhexyl Phthalate; Environment; Environmental Exposure; Environmental Pollutants; Humans; Nutrition Surveys; Phthalic Acids; Risk; Risk Assessment; Safety

2017
Dibutyl Phthalate Rather than Monobutyl Phthalate Facilitates Contact Hypersensitivity to Fluorescein Isothiocyanate in a Mouse Model.
    Biological & pharmaceutical bulletin, 2017, Nov-01, Volume: 40, Issue:11

    Topics: Animals; CHO Cells; Cricetulus; Dermatitis, Contact; Dibutyl Phthalate; Disease Models, Animal; Female; Fluorescein-5-isothiocyanate; Mice, Inbred BALB C; Phthalic Acids; TRPA1 Cation Channel

2017
Urinary phthalate metabolites concentrations and symptoms of depression in an elderly population.
    The Science of the total environment, 2018, Jun-01, Volume: 625

    Topics: Aged; Depression; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Exposure; Environmental Pollutants; Female; Humans; Male; Phthalic Acids

2018
Increased risk of phthalates exposure for recurrent pregnancy loss in reproductive-aged women.
    Environmental pollution (Barking, Essex : 1987), 2018, Volume: 241

    Topics: Adult; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Exposure; Environmental Pollutants; Female; Humans; Phthalic Acids; Pregnancy; Pregnancy Outcome; Reproduction; Risk; Taiwan

2018
Effects of dibutyl phthalate and di(2-ethylhexyl) phthalate with their metabolites on CYP2C9*1 and CYP2C19*1 activities in vitro.
    Journal of pharmaceutical and biomedical analysis, 2018, Oct-25, Volume: 160

    Topics: Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2C9 Inhibitors; Dibutyl Phthalate; Diethylhexyl Phthalate; Humans; Inhibitory Concentration 50; Microsomes; Phthalic Acids

2018
Temporal Trends of Urinary Phthalate Concentrations in Two Populations: Effects of REACH Authorization after Five Years.
    International journal of environmental research and public health, 2018, 09-06, Volume: 15, Issue:9

    Topics: Adult; Dibutyl Phthalate; Diethylhexyl Phthalate; Endocrine Disruptors; Environmental Exposure; Environmental Pollutants; Female; Healthy Volunteers; Humans; Male; Middle Aged; Phthalic Acids; Tandem Mass Spectrometry

2018
Effects of two environmental endocrine disruptors di-n-butyl phthalate (DBP) and mono-n-butyl phthalate (MBP) on human sperm functions in vitro.
    Reproductive toxicology (Elmsford, N.Y.), 2019, Volume: 83

    Topics: Adult; Dibutyl Phthalate; Endocrine Disruptors; Humans; Male; Phthalic Acids; Sperm Motility; Spermatozoa; Tyrosine; Young Adult

2019
Steady-State Human Pharmacokinetics of Monobutyl Phthalate Predicted by Physiologically Based Pharmacokinetic Modeling Using Single-Dose Data from Humanized-Liver Mice Orally Administered with Dibutyl Phthalate.
    Chemical research in toxicology, 2019, 02-18, Volume: 32, Issue:2

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Dibutyl Phthalate; Female; Humans; Liver; Male; Mice; Microsomes, Liver; Models, Animal; Phthalic Acids; Plasticizers; Rats; Rats, Sprague-Dawley; Serum Albumin; Spectrophotometry, Ultraviolet

2019
Phthalate exposure and cumulative risk in a Chinese newborn population.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:8

    Topics: Adult; Asian People; Child; China; Cross-Sectional Studies; Dibutyl Phthalate; Environmental Exposure; Environmental Pollutants; Female; Humans; Infant, Newborn; No-Observed-Adverse-Effect Level; Phthalic Acids; Pregnancy; Public Health; Retrospective Studies; Risk Assessment; Tandem Mass Spectrometry

2019
Di-n-butyl phthalate, butylbenzyl phthalate, and their metabolites exhibit different apoptotic potential in human peripheral blood mononuclear cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 133

    Topics: Apoptosis; Calcium; Caspase 3; Caspase 8; Caspase 9; Dibutyl Phthalate; Humans; Lymphocytes; Membrane Potential, Mitochondrial; Monocytes; Necrosis; Phthalic Acids; Plasticizers

2019
SREBP2-STARD4 is involved in synthesis of cholesteryl ester stimulated by mono-butyl phthalate in MLTC-1 cells.
    Environmental toxicology, 2020, Volume: 35, Issue:3

    Topics: Animals; Cell Line, Tumor; Cholesterol Esters; Dibutyl Phthalate; Down-Regulation; Male; Membrane Transport Proteins; Mice; Phthalic Acids; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Signal Transduction; Sterol Regulatory Element Binding Protein 2

2020
Monobutyl phthalate (MBP) can dysregulate the antioxidant system and induce apoptosis of zebrafish liver.
    Environmental pollution (Barking, Essex : 1987), 2020, Volume: 257

    Topics: Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Dibutyl Phthalate; Kelch-Like ECH-Associated Protein 1; Liver; Malondialdehyde; NF-E2-Related Factor 2; Oxidative Stress; Phthalic Acids; Water Pollutants, Chemical; Zebrafish; Zebrafish Proteins

2020
Development and Validation of an Analytical Method for Quantitation of Monobutylphthalate, a Metabolite of Di-n-Butylphthalate, in Rat Plasma, Amniotic Fluid, Fetuses and Pups by UPLC-MS/MS.
    Journal of analytical toxicology, 2020, May-18, Volume: 44, Issue:4

    Topics: Amniotic Fluid; Animals; Calibration; Chromatography, Liquid; Dibutyl Phthalate; Female; Lactation; Limit of Detection; Phthalic Acids; Plasma; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry

2020
Treatment performance and microbial response to dibutyl phthalate contaminated wastewater in vertical flow constructed wetland mesocosms.
    Chemosphere, 2020, Volume: 246

    Topics: Adsorption; Bacteria; Biodegradation, Environmental; Dibutyl Phthalate; Flavobacterium; Fungi; Oxalobacteraceae; Phthalic Acids; Wastewater; Wetlands

2020
Degradation of dibutyl phthalate (DBP) by a bacterial consortium and characterization of two novel esterases capable of hydrolyzing PAEs sequentially.
    Ecotoxicology and environmental safety, 2020, Jun-01, Volume: 195

    Topics: Actinobacteria; Burkholderiaceae; Dibutyl Phthalate; Environmental Pollutants; Esterases; Genes, Bacterial; Hydrolysis; Lipase; Microbial Consortia; Phthalic Acids; Plasticizers

2020
In utero exposure to DBP stimulates release of GnRH by increasing the secretion of PGE2 in the astrocytes of the hypothalamus in the offspring mice.
    Ecotoxicology and environmental safety, 2020, Jul-15, Volume: 198

    Topics: Animals; Astrocytes; Bodily Secretions; Dibutyl Phthalate; Dinoprostone; Endocrine Disruptors; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Male; Mice; Neurons; Phthalic Acids; Pregnancy; Reproduction

2020
Human Erythrocytes Exposed to Phthalates and Their Metabolites Alter Antioxidant Enzyme Activity and Hemoglobin Oxidation.
    International journal of molecular sciences, 2020, Jun-24, Volume: 21, Issue:12

    Topics: Adult; Antioxidants; Catalase; Dibutyl Phthalate; Erythrocytes; Glutathione Peroxidase; Healthy Volunteers; Hemoglobins; Humans; Middle Aged; Oxidation-Reduction; Phthalic Acids; Plasticizers; Reactive Oxygen Species; Superoxide Dismutase; Teratogens; Young Adult

2020
Dibutyl phthalate promotes juvenile Sertoli cell proliferation by decreasing the levels of the E3 ubiquitin ligase Pellino 2.
    Environmental health : a global access science source, 2020, 08-01, Volume: 19, Issue:1

    Topics: Animals; Cell Proliferation; Dibutyl Phthalate; Male; Mice; Mice, Inbred BALB C; Nuclear Proteins; Phthalic Acids; Plasticizers; Sertoli Cells; Ubiquitin-Protein Ligases

2020
Monobutyl phthalate (MBP) induces energy metabolism disturbances in the gills of adult zebrafish (Danio rerio).
    Environmental pollution (Barking, Essex : 1987), 2020, Volume: 266, Issue:Pt 1

    Topics: Animals; Dibutyl Phthalate; Energy Metabolism; Gills; Phthalic Acids; Zebrafish

2020
Genotoxic risk assessment and mechanism of DNA damage induced by phthalates and their metabolites in human peripheral blood mononuclear cells.
    Scientific reports, 2021, 01-18, Volume: 11, Issue:1

    Topics: Adult; Cells, Cultured; Dibutyl Phthalate; DNA Damage; Healthy Volunteers; Humans; Leukocytes, Mononuclear; Mutagenicity Tests; Phthalic Acids; Plasticizers; Risk Assessment; Young Adult

2021
Mono-n-Butyl Phthalate Distributes to the Mouse Ovary and Liver and Alters the Expression of Phthalate-Metabolizing Enzymes in Both Tissues.
    Toxicological sciences : an official journal of the Society of Toxicology, 2021, 08-30, Volume: 183, Issue:1

    Topics: Animals; Chromatography, Liquid; Dibutyl Phthalate; Female; Liver; Mice; Ovary; Phthalic Acids; Tandem Mass Spectrometry

2021
Environmentally relevant perinatal exposure to DBP disturbs testicular development and puberty onset in male mice.
    Toxicology, 2021, Volume: 459

    Topics: Animals; Blood-Testis Barrier; Dibutyl Phthalate; Endocrine Disruptors; Female; Gonadal Steroid Hormones; Leydig Cells; Male; Maternal Exposure; Mice; Mice, Inbred BALB C; Phthalic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Sexual Maturation; Spermatogenesis; Steroids; Testis

2021
The selected epigenetic effects of phthalates: DBP, BBP and their metabolites: MBP, MBzP on human peripheral blood mononuclear cells (In Vitro).
    Toxicology in vitro : an international journal published in association with BIBRA, 2022, Volume: 82

    Topics: Dibutyl Phthalate; Epigenesis, Genetic; Humans; Leukocytes, Mononuclear; Phthalic Acids; Proto-Oncogene Proteins c-bcl-2

2022
Di-n-Butyl Phthalate and Its Monoester Metabolite Impairs Steroid Hormone Biosynthesis in Human Cells: Mechanistic In Vitro Studies.
    Cells, 2022, 09-27, Volume: 11, Issue:19

    Topics: Adenosine Monophosphate; Androstenedione; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Dibutyl Phthalate; Humans; Hydrocortisone; Male; Phthalic Acids; Progesterone; Steroid 11-beta-Hydroxylase; Steroids; Superoxides; Testosterone

2022
Interaction between Phthalate Ester and Rice Plants: Novel Transformation Pathways and Metabolic-Network Perturbations.
    Environmental science & technology, 2023, 06-20, Volume: 57, Issue:24

    Topics: Amino Acids; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Exposure; Environmental Pollutants; Humans; Metabolic Networks and Pathways; Molecular Docking Simulation; Oryza; Phthalic Acids; Proteomics

2023
DBP exposure induces thyroid inflammatory impairment through activating AKT/NF-κB/NLRP3 signaling.
    Ecotoxicology and environmental safety, 2023, Oct-01, Volume: 264

    Topics: Animals; Dibutyl Phthalate; Male; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Proto-Oncogene Proteins c-akt; Rats; Thyroid Gland

2023