mono-n-demethyladinazolam has been researched along with adinazolam in 17 studies
| Studies (mono-n-demethyladinazolam) | Trials (mono-n-demethyladinazolam) | Recent Studies (post-2010) (mono-n-demethyladinazolam) | Studies (adinazolam) | Trials (adinazolam) | Recent Studies (post-2010) (adinazolam) |
|---|---|---|---|---|---|
| 20 | 12 | 0 | 93 | 37 | 2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 12 (70.59) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hester, JB; Rudzik, AD; VonVoigtlander, PF | 1 |
| Ekernäs, SA; Fleishaker, JC; Grahnén, A; Hulst, LK | 1 |
| Fleishaker, JC; Wright, CE | 1 |
| Brouwer, KL; Dukes, GE; Fleishaker, JC; Hak, LJ; Koruda, M; Songer, SS; Suttle, AB | 1 |
| Fleishaker, JC; Friedman, H; Hulst, LK; Smith, TC | 1 |
| Fleishaker, JC; Kroboth, PD; Maxwell, RA; Smith, RB; Van Thiel, DH | 1 |
| Fleishaker, JC; Friedman, H; Pollock, SR; Smith, TC | 1 |
| Fleishaker, JC; Phillips, JP | 1 |
| Day, JS; Francis, JW; Sethy, VH | 1 |
| Greenblatt, DJ; Locniskar, A | 1 |
| Bryan, W; Fraser, AD | 1 |
| Brouwer, KL; Fleishaker, JC; Golden, PL; Jewell, RC; Lyon, J; Millikin, S; Warner, PE | 1 |
| Chambers, JH; Fleishaker, JC | 1 |
| Conrad, J; Cutler, NR; Fleishaker, JC; Sisson, TA; Sramek, JJ; Veroff, AE | 1 |
| Ajir, K; Anderson, D; Chambers, JH; Fleishaker, JC; Lin, KM; Nuccio, I; Poland, RE; Smith, M; Zheng, Y | 1 |
| Duan, SX; Fleishaker, JC; Greenblatt, DJ; Shader, RI; Venkatakrishnan, K; von Moltke, LL | 1 |
| Corbett, KE; Culm, KE; Ehrenberg, BL; Fleishaker, JC; Greenblatt, DJ; Harmatz, JS; Venkatakrishnan, K | 1 |
10 trial(s) available for mono-n-demethyladinazolam and adinazolam
| Article | Year |
|---|---|
Pharmacokinetics and pharmacodynamics of adinazolam and N-desmethyladinazolam after oral and intravenous dosing in healthy young and elderly volunteers.
Topics: Administration, Oral; Adult; Aged; Aging; Analysis of Variance; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Female; Humans; Infusions, Intravenous; Male; Psychomotor Performance | 1992 |
Pharmacokinetic and pharmacodynamic comparison of immediate-release and sustained-release adinazolam mesylate tablets after single- and multiple-dose administration.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Tablets | 1992 |
Ranitidine does not alter adinazolam pharmacokinetics or pharmacodynamics.
Topics: Adult; Analysis of Variance; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Male; Psychomotor Performance; Ranitidine | 1992 |
Clinical pharmacology of adinazolam and N-desmethyladinazolam mesylate following single intravenous infusions of each compound in health volunteers.
Topics: Adolescent; Adult; Analysis of Variance; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Humans; Injections, Intravenous; Male; Middle Aged; Psychomotor Performance; Reference Values; Uric Acid | 1992 |
Clinical pharmacology of adinazolam and N-desmethyladinazolam mesylate after single oral doses of each compound in healthy volunteers.
Topics: Administration, Oral; Adolescent; Adult; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Humans; Male; Psychomotor Performance; Reference Values; Uric Acid | 1990 |
Adinazolam pharmacokinetics and behavioral effects following administration of 20-60 mg oral doses of its mesylate salt in healthy volunteers.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Dose-Response Relationship, Drug; Humans; Hypnotics and Sedatives; Middle Aged; Psychomotor Performance | 1989 |
Effects of probenecid on the pharmacokinetics and pharmacodynamics of adinazolam in humans.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Double-Blind Method; Drug Interactions; Drug Synergism; Humans; Kidney; Male; Memory, Short-Term; Probenecid; Psychomotor Performance; Uric Acid | 1994 |
Psychomotor and memory effects of two adinazolam formulations assessed by a computerized neuropsychological test battery.
Topics: Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Computers; Delayed-Action Preparations; Humans; Memory; Neuropsychological Tests; Psychomotor Performance; Single-Blind Method; Tablets | 1993 |
The pharmacokinetics and pharmacodynamics of adinazolam: multi-ethnic comparisons.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Asian People; Benzodiazepines; Black People; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Psychomotor Performance; White People | 1997 |
Kinetics and dynamics of intravenous adinazolam, N-desmethyl adinazolam, and alprazolam in healthy volunteers.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Cross-Over Studies; Electroencephalography; Emotions; Half-Life; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Psychomotor Performance | 2005 |
7 other study(ies) available for mono-n-demethyladinazolam and adinazolam
| Article | Year |
|---|---|
1-(Aminoalkyl)-6-aryl-4-H-s-triazolo[4,3-a][1,4]benzodiazepines with antianxiety and antidepressant activity.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Apomorphine; Behavior, Animal; Benzodiazepines; Body Temperature; Drug Synergism; Male; Mice; Oxotremorine; Oxygen; Structure-Activity Relationship; Yohimbine | 1980 |
Comparison of adinazolam pharmacokinetics and effects in healthy and cirrhotic subjects.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Female; Humans; Liver Cirrhosis; Male; Middle Aged | 1991 |
The effect of proadifen on the metabolism of adinazolam.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Flunitrazepam; In Vitro Techniques; Male; Mice; Proadifen | 1986 |
High-performance liquid chromatographic assay of adinazolam and its desmethyl metabolite.
Topics: Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Humans; Spectrophotometry, Ultraviolet | 1988 |
Evaluation of the Abbott TDx serum benzodiazepine immunoassay for the analysis of lorazepam, adinazolam, and N-desmethyladinazolam.
Topics: Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Benzodiazepines; Fluorescence Polarization Immunoassay; Humans; Hypnotics and Sedatives; Lorazepam; Reagent Kits, Diagnostic | 1995 |
The lack of effect of smoking on the pharmacokinetics and pharmacodynamics of adinazolam and N-demethyladinazolam.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Half-Life; Humans; Male; Metabolic Clearance Rate; Psychomotor Performance; Smoking | 1994 |
Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
Topics: Anti-Anxiety Agents; Aryl Hydrocarbon Hydroxylases; Benzodiazepines; Biotransformation; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; In Vitro Techniques; Ketoconazole; Kinetics; Macrolides; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1998 |