monensin and alborixin

monensin has been researched along with alborixin* in 2 studies

Other Studies

2 other study(ies) available for monensin and alborixin

ArticleYear
Anticoccidial activity of alborixin.
    The Journal of parasitology, 1987, Volume: 73, Issue:1

    Alborixin, a polyether antibiotic with ionophore properties, was evaluated to determine the effect of the drug on weight gain of chickens and to define the anticoccidial spectrum of activity. The 50-ppm concentration in the diet was identified as the maximum level that did not significantly reduce weight gain beyond that of monensin (standard drug); consequently, the drug was evaluated for anticoccidial activity at this dilution. At the 50-ppm level, alborixin demonstrated broad-spectrum anticoccidial activity; however, the drug lacked Eimeria necatrix efficacy. Monensin and maduramycin were significantly more efficacious than alborixin as a treatment for several species of Eimeria. Higher concentrations of alborixin (greater than 50 ppm) appear essential to achieve broad-spectrum and comparable anticoccidial activity, however, these levels substantially depressed weight gains. Alborixin is similar to many other polyethers in that weight gains are adversely affected at drug levels essential for solid broad-spectrum anticoccidial activity.

    Topics: Animals; Body Weight; Chickens; Coccidiostats; Eimeria; Monensin; Pyrans

1987
The influence of pH on the conductance of lipid bimolecular membranes in relation to the alkaline ion transport induced by carboxylic carriers grisorixin, alborixin and monensin.
    Biochimica et biophysica acta, 1978, Aug-17, Volume: 511, Issue:3

    The influence of the pH on the stability and stoichiometry of the complexes formed by carboxylic-antibiotics such as grisorixin, alborixin and monensin with alkaline and alkaline earth cations has been investigated. The maximum values of bimolecular lipid membrane conductance are obtained with grisorixin and potassium ion. The conductance-pH curves show a very pronounced maximum in the neutral pH range. The results are analysed on the basis of a dimeric form of the ionophore in the complex and the possibility of having several charged complexes resulting from an heterogeneous reaction, the number of each complexed form depending on the pH of the bulk solutions.

    Topics: Anti-Bacterial Agents; Calcium; Cations; Cesium; Chemical Phenomena; Chemistry, Physical; Electric Conductivity; Furans; Hydrogen-Ion Concentration; Ionophores; Lipids; Lithium; Membranes, Artificial; Monensin; Nigericin; Potassium; Pyrans; Sodium

1978