monastrol has been researched along with coumarin* in 1 studies
1 other study(ies) available for monastrol and coumarin
Article | Year |
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Discovery of coumarin-monastrol hybrid as potential antibreast tumor-specific agent.
Development of new, targeted antibreast cancer drug which can treat both the hormone receptor (positive and negative) breast cancers is a very challenging task. The concept of molecular hybridization led us to discover a novel class of coumarin-monastrol hybrid, as a novel breast cancer agent which selectively induce apoptosis in both primary and metastatic breast cancer cell lines. Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Proliferation; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Thiones; Tumor Cells, Cultured | 2013 |