mometasone-furoate has been researched along with clobetasone-butyrate* in 1 studies
1 trial(s) available for mometasone-furoate and clobetasone-butyrate
| Article | Year |
|---|---|
Inhibition of elicitation of contact dermatitis in humans by mometasone furoate: evaluation by means of 20-MHz B scanning associated with image analysis.
Mometasone furoate (MF) is a new strongly lipophilic steroid which has an anti-inflammatory effect as evaluated by in vivo and in vitro studies.. The objective of the present study was to investigate the degree of inhibition of experimental allergic contact dermatitis induced by the treatment with MF.. The therapeutic effect was evaluated by an echographic method associated with image analysis. MF activity was compared to that of hydrocortisone acetate 0.5% (Cortaid Cream, Lachifarma), clobetasone butyrate 0.05% (Eumovate Cream, Glaxo) and clobetasol propionate 0.05% (Clobesol Cream, Glaxo), classified respectively as weak, moderately potent and very potent steroids.. The different corticosteroid formulations employed for inhibiting experimentally induced contact dermatitis reflect the expected rank order of efficacy.. MF behaves like clobetasol butyrate ranking as a moderately potent corticosteroid. Topics: Administration, Topical; Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents; Clobetasol; Dermatitis, Allergic Contact; Female; Humans; Hydrocortisone; Image Enhancement; Middle Aged; Mometasone Furoate; Patch Tests; Pregnadienediols; Reproducibility of Results; Skin; Ultrasonography | 1997 |