molsidomine has been researched along with arginine in 151 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 107 (70.86) | 18.2507 |
| 2000's | 39 (25.83) | 29.6817 |
| 2010's | 5 (3.31) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braun, MS; Heckenberger, RE; Klockenbusch, W; Schröder, H; Schrör, K; Strobach, H | 1 |
| Dembinska-Kiéc, A; Pallapies, D; Peskar, BA; Simmet, T; Thelen, KI | 1 |
| Andersson, KE; Hedlund, H; Holmquist, F | 1 |
| Duarte, ID; Ferreira, SH | 1 |
| Bucher, B; Ouedraogo, S; Paya, D; Stoclet, JC; Tschöpl, M | 1 |
| Schini, VB; Vanhoutte, PM | 2 |
| Philippu, A; Prast, H | 1 |
| Andersson, KE; Igawa, Y; Mattiasson, A; Persson, K | 1 |
| Benyó, Z; Csáki, C; Kovách, AG; Reivich, M; Szabó, C | 1 |
| Ellis, JL; Undem, BJ | 1 |
| Nagao, T; Vanhoutte, PM | 1 |
| Eccles, CU; Haberny, KA; Pou, S | 1 |
| Dembińska-Kieć, A; Pallapies, D; Peskar, BA; Simmet, T; Thelen, K | 1 |
| Duarte, ID; Ferreira, SH; Lorenzetti, BB | 1 |
| Bianchi, S; Gambassi, F; Lupini, M; Mannaioni, PF; Masini, E; Mugnai, L; Pistelli, A | 1 |
| Förster, S; Schrör, K; Woditsch, I | 2 |
| Dembinska-Kiec, A; Pallapies, D; Peskar, BA; Peskar, BM; Simmet, T | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA; Phillips, K | 1 |
| Berdeaux, A; Drieu la Rochelle, C; Giudicelli, JF; Gosgnach, M; Richard, V | 1 |
| Biondi, ML; Dousa, T; Romero, JC; Vanhoutte, P | 1 |
| Akarid, K; Desforges, B; Gougerot-Pocidalo, MA; Sinet, M | 1 |
| Giles, WR; Han, X; Shimoni, Y | 1 |
| Drapier, JC; Hirling, H; Kaldy, P; Kühn, LC; Wietzerbin, J | 2 |
| Bockaert, J; Culcasi, M; Gaven, F; Lafon-Cazal, M; Pietri, S | 1 |
| Adnot, S; Blouquit, Y; Carville, C; Eddahibi, S; Raffestin, B | 1 |
| Aleppo, G; Canonico, PL; Scapagnini, U; Sortino, MA | 1 |
| Aleskowitch, TD; Flavahan, NA; Murray, PA | 1 |
| Cunningham, JM; Delaney, CA; Elphick, MR; Green, IC; Green, MH; Mabley, JG | 1 |
| Koch, B; Lutz-Bucher, B | 1 |
| Iadecola, C; Xu, X; Zhang, F | 1 |
| Garg, LC; Guzman, NJ; Madsen, KM; Tisher, CC; Tojo, A | 1 |
| Conanan, ND; Ellis, JL | 1 |
| Boulu, RG; Buisson, A; Lakhmeche, N; Plotkine, M; Verrecchia, C | 1 |
| Balla, I; Dawson, TM; Kovách, AG; Lohinai, Z; Marczis, J; Snyder, SH | 1 |
| Mora, F; Porras, A; Segovia, G | 1 |
| Akesson, B; Lundquist, I; Panagiotidis, G; Rydell, EL | 1 |
| Di Rosa, M; Ialenti, A; Ianaro, A; Sautebin, L | 1 |
| Bockaert, J; Fagni, L; Lafon-Cazal, M; Lerner-Natoli, M; Manzoni, O; Rondouin, G | 1 |
| Gryglewski, RJ; Swies, J | 1 |
| Shibata, S; Tanaka, T; Watanabe, S; Yamamoto, Y | 1 |
| Bousquet, J; Dugas, B; Paul-Eugène, N; Pène, J | 1 |
| Abelli, L; Barnes, PJ; Belvisi, MG; Polak, JM; Springall, DR; Tadjkarimi, S; Ward, JK; Yacoub, MH | 1 |
| Gourine, AV | 1 |
| Furukawa, T; Kohno, H; Taketani, S; Tokunaga, R | 1 |
| Balla, I; Kovách, AG; Lohinai, Z; Marczis, J; Vass, Z | 1 |
| Antunes, E; Bizeto, L; de Nucci, G; Mariani-Pedroso, SR; Zatz, R | 1 |
| Barnes, PJ; Belvisi, MG; Tadjkarimi, S; Ward, JK; Yacoub, MH | 1 |
| Hughes, H; Joly, GA; Schini, VB; Vanhoutte, PM | 1 |
| Cunningham, JM; Delaney, CA; Green, IC; Karmiris, V; Southern, C | 1 |
| Costa, A; Forsling, ML; Grossman, A; Trainer, P; Windle, R; Yasin, S | 1 |
| Eigler, A; Endres, S; Moeller, J | 1 |
| Alanko, J; Lähteenmäki, T; Mucha, I; Riutta, A; Sievi, E; Vapaatalo, H | 1 |
| Pastor, CM; Payen, DM | 1 |
| Caputi, AP; Cook, JA; Halushka, PV; Zingarelli, B | 1 |
| Bosnjak, ZJ; Coughlan, MG; Kampine, JP; Kenny, D; Montgomery, RR; Warltier, DC | 1 |
| Baczyńska, E; Dembińska-Kieć, A; Goldsztajn, P; Gryglewski, R; Miszczuk-Jamska, B; Przewłocki, R; Sowa, G; Wybrańska, I | 1 |
| Damais, C; Dugas, B; Kolb, JP; Paul-Eugène, N; Yamaoka, K | 1 |
| Illiano, S; Mombouli, JV; Olmos, L; Vanhoutte, PM | 1 |
| Brian, JE; Hicks, KK; Kennedy, RH; Seifen, E | 1 |
| Arock, M; Debré, P; Dugas, B; Kilchherr, E; Kolb, JP; Mossalayi, MD; Ouaaz, F; Paul-Eugène, N | 1 |
| Mohaupt, M; Schoecklmann, HO; Schulze-Lohoff, E; Sterzel, RB | 1 |
| Arock, M; Bécherel, PA; Debré, P; Dugas, B; Le Goff, L; Mossalayi, MD | 1 |
| Kaeffer, N; Richard, V; Thuillez, C; Tron, C | 1 |
| Bode-Böger, SM; Böger, RH; Frölich, JC; Gerecke, U | 1 |
| Clarke, GA; Gross, GJ; Pieper, GM | 1 |
| Arnet, U; Ganten, D; Lüscher, TF; Noll, G; Novosel, D; Tschudi, MR | 1 |
| Fung, KP; Wu, J; Wu, TW; Zeng, LH | 1 |
| Bosnjak, ZJ; Coughlan, MG; Kampine, JP; Kenny, D; Warltier, DC | 1 |
| Kubes, P | 1 |
| Flammer, J; Lüscher, TF; Meyer, P | 1 |
| Cosentino, F; Katusić, ZS; Sill, JC | 1 |
| Besser, M; Costa, A; Grossman, A; Trainer, P | 1 |
| Adams, GE; Stratford, IJ; Szabo, C; Thiemermann, C; Vane, JR; Wood, PJ | 1 |
| Hiraoka, M; Muramatsu, I; Sudo, M; Tsuchida, S | 1 |
| Galluser, M; Raul, F; Schleiffer, R | 1 |
| Blanc, T; Kaeffer, N; Richard, V; Thuillez, C; Tron, C | 1 |
| Holzer, P; Jocic, M; Peskar, BA | 1 |
| Cobbe, SM; Kane, KA; Martynyuk, AE; Rankin, AC | 1 |
| Dikshit, M; Shukla, A; Srimal, RC | 1 |
| Brunetti, L; Preziosi, P; Ragazzoni, E; Vacca, M | 1 |
| Balligand, JL; Han, X; Kelly, RA; Kobzik, L; Smith, TW | 1 |
| Fuhrmann, M; Hippenstiel, S; Krull, M; Podzuweit, T; Suttorp, N | 1 |
| Sadoff, JD; Scholz, PM; Tse, J; Weiss, HR | 1 |
| Allescher, HD; Huber, A; Kurjak, M; Schusdziarra, V; Trudrung, P | 1 |
| Besser, M; Delitala, G; Dettori, A; Fanciulli, G; Grossman, AB; Korbonits, M; Oliva, O; Pala, A; Trainer, PJ | 1 |
| Raul, F; Schleiffer, R | 1 |
| Adams, MR; Celermajer, DS; Hailstones, D; Jessup, W | 1 |
| Cook, DI; Poronnik, P; Tuch, BE; Weinhaus, AJ | 1 |
| Baux, G; Fossier, P; Mothet, JP; Schirar, A; Tauc, L | 1 |
| Borderie, D; Calmus, Y; Houssin, D; Sogni, P; Soubrane, O; Zhang, B | 1 |
| Cunningham, JM; Green, IC; Mabley, JG | 1 |
| Fisher, PW; Huang, YC; Nozik-Grayck, E; Piantadosi, CA | 1 |
| Greenlees, C; Martorana, PA; Wadsworth, RM; Wainwright, CL | 1 |
| Avogadri, E; Camanni, F; Ghigo, E; Grottoli, S; Maccario, M; Oleandri, SE; Procopio, M | 1 |
| Inagaki, N; Musoh, K; Nagai, H; Nakamura, N; Ueda, Y | 1 |
| Kostowski, W; Krzaścik, P | 1 |
| Demontis, MP; Emanueli, C; Madeddu, P; Varoni, MV; Volpe, AR | 1 |
| Bode-Böger, SM; Böger, RH; Frölich, JC; Galland, A | 1 |
| Hars, B | 1 |
| Alves-Do-Prado, W; Ambiel, CR; Silva, HM | 1 |
| Kim, HS; Kim, SH; Son, YR | 1 |
| Baux, G; Chaubourt, E; De La Porte, S; Fossier, P; Israël, M; Leprince, C | 1 |
| Baribeau, J; Berkenbosch, JW; Perreault, T | 1 |
| Garfield, RE; Marx, S; Saade, GR; Vedernikov, Y | 1 |
| Iversen, J; Strandgaard, S; Wang, D | 1 |
| Andersson, K; Fujiwara, M; Persson, K | 1 |
| Mueller, AR; Neuhaus, P; Nüssler, AK; Nüssler, NC; Platz, KP; Radke, C; Schirmeier, A; Schmitz, V; Seehofer, D | 1 |
| Tiritilli, A | 1 |
| Aonuma, H; Nagayama, T; Takahata, M | 1 |
| Arnolda, LF; Llewellyn-Smith, IJ; McKitrick, DJ; Minson, JB | 1 |
| Abdallahi, OM; Bensalem, H; De Reggi, M; Diagana, M; Gharib, B | 1 |
| De Iuri, L; Imbrogno, S; Mazza, R; Tota, B | 1 |
| An, GS; Liu, NK; Nie, SH; Tang, CS; Wang, SH; Zheng, HZ | 1 |
| Alfke, H; Barry, JJ; Bergen, S; Kalinowski, M; Klose, KJ; Wagner, HJ | 1 |
| Assem, EK; Moulson, A; Pearce, FL; Peh, KH; Wan, BY | 1 |
| Mazza, R; Pellegrino, D; Randall, DJ; Sprovieri, E; Tota, B | 1 |
| Mueller, AR; Neuhaus, P; Nüssler, AK; Nüssler, NC; Platz, KP; Radke, C; Schirmeier, A; Stange, B; Warnecke, HB | 1 |
| Bednarz, S; Grodzicki, T; Janicki, K; Pawlik, T | 1 |
| Aoyagi, K | 1 |
| Ferreira, SH; Parada, CA; Vivancos, GG | 1 |
| Ogonowski, AA; Smith, JB | 1 |
| Daig, U; Krämer, S; Liefeldt, L; Martini, S; Neumayer, HH; Peters, H; Rückert, M; Schäper, F | 1 |
| Alexander, B; Benjamin, IS; Li, X | 1 |
| Häusler, M; Heckert, C; Lobeck, H; Müller, AR; Neuhaus, P; Platz, KP | 1 |
| Sadan, G; Tasatargil, A | 1 |
| Bieber, A; Chung, E; Day, E; Ohgami, Y; Quock, RM | 1 |
| Déciga-Campos, M; López-Muñoz, FJ | 1 |
| Jantos, H; Monti, JM | 2 |
| Sadan, G; Tuncel, BI | 1 |
| Chou, YC; Chu, JJ; Chu, Y; Chueh, HY; Lin, PJ; Liu, HP; Wu, YC | 1 |
| Palmerini, CA; Pellegrino, D; Tota, B | 1 |
| Chander, V; Chopra, K | 3 |
| Guimarães, FS; Joca, SR | 1 |
| Bieber, AJ; Burke, B; Chung, E; Doss, JC; Ohgami, Y; Quock, RM | 1 |
| Faggio, C; Pidalà, P; Trischitta, F | 1 |
| Chakraborti, A; Gulati, K; Ray, A | 1 |
| Acierno, R; Amelio, D; Gattuso, A; Guerrieri, A; Mannarino, C; Tota, B | 1 |
| Bishnoi, M; Chopra, K; Kulkarni, SK | 1 |
| Amelio, D; Cerra, MC; Garofalo, F; Pellegrino, D; Sidell, BD; Tota, B | 1 |
| Davidge, ST; Sankaralingam, S; Xu, H | 1 |
| Braam, B; Goldschmeding, R; Joles, JA; Koeners, MP; van der Giezen, DM | 1 |
| Ahn, JH; Choe, MA; Han, JA; Kim, JI; Kim, KH | 1 |
| Chung, E; Ohgami, Y; Quock, RM | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
1 review(s) available for molsidomine and arginine
| Article | Year |
|---|---|
Effects of cytokines and nitric oxide donors on insulin secretion, cyclic GMP and DNA damage: relation to nitric oxide production.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cells, Cultured; Cyclic GMP; Cytokines; DNA; DNA Damage; Free Radicals; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Vasodilator Agents | 1994 |
2 trial(s) available for molsidomine and arginine
| Article | Year |
|---|---|
Comparison among the effects of arginine, a nitric oxide precursor, isosorbide dinitrate and molsidomine, two nitric oxide donors, on hormonal secretions and blood pressure in man.
Topics: Adult; Arginine; Blood Glucose; Blood Pressure; Hormones; Humans; Isosorbide Dinitrate; Male; Molsidomine; Nitric Oxide; Vasodilator Agents | 1997 |
Differential inhibition of human platelet aggregation and thromboxane A2 formation by L-arginine in vivo and in vitro.
Topics: Adult; Antithrombins; Arginine; Blood Platelets; Cyclic GMP; Enzyme Inhibitors; Humans; In Vitro Techniques; Infusions, Intravenous; Male; Molsidomine; Nitric Oxide Synthase; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane A2; Thromboxane B2; Thromboxanes | 1998 |
148 other study(ies) available for molsidomine and arginine
| Article | Year |
|---|---|
Prostacyclin rather than nitric oxide lowers human umbilical artery tone in vitro.
Topics: Arginine; Bradykinin; Cyclic GMP; Epoprostenol; Female; Histamine; Humans; Iloprost; In Vitro Techniques; Indomethacin; Molsidomine; Muscle Contraction; Nitric Oxide; Nitroarginine; Serotonin; Umbilical Arteries; Vasodilation | 1992 |
Effect of 3-morpholinosydnonimine (SIN-1) and NG-nitro-L-arginine (NNA) on isolated perfused anaphylactic guinea-pig hearts.
Topics: 6-Ketoprostaglandin F1 alpha; Anaphylaxis; Animals; Antihypertensive Agents; Arginine; Coronary Circulation; Guinea Pigs; Heart; Leukotriene B4; Male; Molsidomine; Nitroarginine; Perfusion; Thromboxane B2; Vasodilator Agents | 1992 |
Characterization of inhibitory neurotransmission in the isolated corpus cavernosum from rabbit and man.
Topics: Animals; Arginine; Electric Stimulation; Humans; Male; Molsidomine; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroarginine; Penis; Rabbits; Synaptic Transmission; Vasodilator Agents | 1992 |
The molecular mechanism of central analgesia induced by morphine or carbachol and the L-arginine-nitric oxide-cGMP pathway.
Topics: Analgesia; Animals; Arginine; Brain; Carbachol; Cyclic GMP; Dinoprostone; Male; Molsidomine; Morphine; Nitric Oxide; Ornithine; Phthalazines; Rats; Rats, Wistar | 1992 |
Role of the L-arginine-NO pathway and of cyclic GMP in electrical field-induced noradrenaline release and vasoconstriction in the rat tail artery.
Topics: Animals; Arginine; Arteries; Atrial Natriuretic Factor; Cyclic GMP; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Purinones; Rats; Tail; Vasoconstriction; Vasodilator Agents | 1992 |
Inhibitors of calmodulin impair the constitutive but not the inducible nitric oxide synthase activity in the rat aorta.
Topics: Amino Acid Oxidoreductases; Animals; Aorta; Arginine; Calmodulin; Cyclic GMP; Drug Interactions; Endothelium, Vascular; Fendiline; Imidazoles; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Inbred Strains; Vasodilator Agents | 1992 |
Nitric oxide releases acetylcholine in the basal forebrain.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Prosencephalon; Rats | 1992 |
Effects of inhibition of the L-arginine/nitric oxide pathway in the rat lower urinary tract in vivo and in vitro.
Topics: Animals; Arginine; Electric Stimulation; Female; In Vitro Techniques; Molsidomine; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Urethra; Urinary Bladder; Urinary Tract; Urinary Tract Physiological Phenomena; Urination; Vasodilator Agents | 1992 |
Role of the L-arginine-nitric oxide pathway in the changes in cerebrovascular reactivity following hemorrhagic hypotension and retransfusion.
Topics: Acetylcholine; Animals; Arginine; Cats; Cerebral Arteries; Endothelium, Vascular; Male; Molsidomine; Muscle, Smooth, Vascular; Nitroarginine; Norepinephrine; Reperfusion; Shock, Hemorrhagic; Vasodilation | 1992 |
Inhibition by L-NG-nitro-L-arginine of nonadrenergic-noncholinergic-mediated relaxations of human isolated central and peripheral airway.
Topics: Arginine; Bronchi; Chymotrypsin; Electric Stimulation; Humans; In Vitro Techniques; Molsidomine; Muscle Relaxation; Nitroarginine; Stereoisomerism; Vasoactive Intestinal Peptide; Vasodilator Agents | 1992 |
Characterization of endothelium-dependent relaxations resistant to nitro-L-arginine in the porcine coronary artery.
Topics: Animals; Arginine; Bradykinin; Coronary Vessels; Dinoprost; Endothelium, Vascular; In Vitro Techniques; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Swine; Vasodilation; Vasodilator Agents | 1992 |
Potentiation of quinolinate-induced hippocampal lesions by inhibition of NO synthesis.
Topics: Animals; Arginine; Hippocampus; Injections, Intraventricular; Molsidomine; Nitric Oxide; Nitroarginine; Quinolinic Acid; Rats; Rats, Sprague-Dawley | 1992 |
Effect of 3-morpholinosydnonimine (SIN-1), NG-nitro-L-arginine (NNA) and NG-monomethyl-L-arginine (NMMA) on isolated anaphylactic guinea-pig hearts.
Topics: Anaphylaxis; Animals; Arginine; Coronary Circulation; Eicosanoids; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Molsidomine; Myocardium; Nitroarginine; omega-N-Methylarginine; Ovalbumin | 1992 |
The molecular mechanism of action of peripheral morphine analgesia: stimulation of the cGMP system via nitric oxide release.
Topics: Analgesia; Animals; Arginine; Cyclic GMP; Male; Methylene Blue; Molsidomine; Morphine; Nitric Oxide; Ornithine; Phthalazines; Rats; Rats, Inbred Strains | 1991 |
The effect of nitric oxide generators on ischemia reperfusion injury and histamine release in isolated perfused guinea-pig heart.
Topics: Animals; Arginine; Calcium; Coronary Vessels; Cytoplasmic Granules; Guinea Pigs; Histamine Release; Male; Mast Cells; Molsidomine; Myocardial Reperfusion Injury; Nitric Oxide; Nitroprusside; omega-N-Methylarginine | 1991 |
On-line measurement of nitric oxide release from organic nitrates in the intact coronary circulation.
Topics: Animals; Arginine; Bradykinin; Coronary Vessels; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Oxyhemoglobins; Rabbits; Substance P; Trypsin; Vasodilation | 1991 |
Effect of carbenoxolone on the biological activity of nitric oxide: relation to gastroprotection.
Topics: Animals; Aorta; Arginine; Carbenoxolone; Gastric Mucosa; Humans; Iloprost; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle Tonus; Neutrophils; Nitric Oxide; Nitroarginine; Nitroprusside; Oxyhemoglobins; Rats; Rats, Inbred Strains; Stomach Ulcer; Vasodilator Agents | 1991 |
Factors affecting the regional haemodynamic responses to glyceryl trinitrate and molsidomine in conscious rats.
Topics: Animals; Arginine; Blood Pressure; Captopril; Enalapril; Heart Rate; Hemodynamics; Hindlimb; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitroglycerin; Rats; Regional Blood Flow; Renal Circulation; Renin-Angiotensin System; Splanchnic Circulation; Vasodilation | 1991 |
The L-arginine-nitric oxide pathway in the canine femoral vascular bed: in vitro and in vivo experiments.
Topics: Acetylcholine; Animals; Arginine; Blood Flow Velocity; Blood Pressure; Bradykinin; Dogs; Drug Interactions; Endothelium, Vascular; Female; Femoral Artery; Heart Rate; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Vasodilation; Vasodilator Agents | 1991 |
Generation of nitric oxide from organic nitrovasodilators during passage through the coronary vascular bed and its role in coronary vasodilation and nitrate tolerance.
Topics: Animals; Arginine; Coronary Vessels; Drug Tolerance; Molsidomine; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Rabbits; Trypsin; Vasodilation; Vasodilator Agents | 1991 |
L-arginine evokes both endothelium-dependent and -independent relaxations in L-arginine-depleted aortas of the rat.
Topics: Acetylcholine; Amino Acids; Animals; Aorta; Arginine; Endothelium, Vascular; Male; Molsidomine; Nitric Oxide; Phenylephrine; Rats; Rats, Inbred Strains; Vasodilation; Vasodilator Agents | 1991 |
Evidences for the existence of endothelium-derived relaxing factor in the renal medulla.
Topics: Acetylcholine; Animals; Arginine; Cyclic GMP; Dogs; Female; Kidney Medulla; Male; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Premedication | 1990 |
Inhibitory effect of nitric oxide on the replication of a murine retrovirus in vitro and in vivo.
Topics: Animals; Antiviral Agents; Arginine; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Friend murine leukemia virus; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred DBA; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Virus Replication | 1995 |
A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Arginine; Carbachol; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; GTP-Binding Proteins; Guanylate Cyclase; Heart Rate; Isoproterenol; Methylene Blue; Molsidomine; Muscarinic Agonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Rabbits; Receptors, Cholinergic; Receptors, Muscarinic; Sinoatrial Node; Thionucleotides | 1995 |
Biosynthesis of nitric oxide activates iron regulatory factor in macrophages.
Topics: Aconitate Hydratase; Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cells, Cultured; Enzyme Induction; Interferon-gamma; Iron-Regulatory Proteins; Kinetics; Leukemia L1210; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mitochondria; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Recombinant Proteins; RNA-Binding Proteins; Tumor Cells, Cultured | 1993 |
Nitric oxide, superoxide and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Catalase; Cell Death; Cells, Cultured; Cerebellum; Cyclic GMP; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Mice; Molsidomine; N-Methylaspartate; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptors, N-Methyl-D-Aspartate; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1993 |
Loss of endothelium-dependent relaxation in proximal pulmonary arteries from rats exposed to chronic hypoxia: effects of in vivo and in vitro supplementation with L-arginine.
Topics: Acetylcholine; Animals; Arginine; Calcimycin; Endothelins; Endothelium, Vascular; Hypoxia; In Vitro Techniques; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Pulmonary Artery; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 1993 |
Involvement of nitric oxide in the regulation of gonadotropin-releasing hormone release from the GT1-1 neuronal cell line.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cyclic GMP; Gonadotropin-Releasing Hormone; Mice; Mice, Transgenic; Molsidomine; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Norepinephrine; Sodium Nitrite | 1994 |
Endothelial and vascular smooth muscle responses are altered after left lung autotransplantation.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Bradykinin; Calcimycin; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Lung Transplantation; Male; Molsidomine; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Pulmonary Artery; Pulmonary Circulation; Transplantation, Autologous; Vasoconstriction; Vasodilation; Vasodilator Agents | 1994 |
Evidence for an inhibitory effect of nitric oxides on neuropeptide secretion from isolated neural lobe of the rat pituitary gland.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arginine Vasopressin; Hemoglobins; In Vitro Techniques; Male; Molsidomine; Neuropeptides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxytocin; Pituitary Gland, Posterior; Rats; Rats, Wistar | 1994 |
SIN-1 reverses attenuation of hypercapnic cerebrovasodilation by nitric oxide synthase inhibitors.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cerebrovascular Circulation; Cyclic GMP; Hypercapnia; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Papaverine; Rats; Rats, Sprague-Dawley; Vasodilation | 1994 |
Nitric oxide inhibits bafilomycin-sensitive H(+)-ATPase activity in rat cortical collecting duct.
Topics: Amino Acid Oxidoreductases; Animals; Anti-Bacterial Agents; Arginine; Cyclic GMP; Enzyme Induction; Ethylmaleimide; Female; In Vitro Techniques; Interferon-gamma; Kidney Tubules, Collecting; Kinetics; Lipopolysaccharides; Macrolides; Macrophages; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Vacuoles | 1994 |
Effect of potassium channel blockers on relaxations to a nitric oxide donor and to nonadrenergic nerve stimulation in guinea pig trachea.
Topics: Animals; Arginine; Charybdotoxin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Molsidomine; Muscle Relaxation; Nitric Oxide; Nitroarginine; Peptides; Potassium Channels; Scorpion Venoms; Trachea | 1994 |
Nitric oxide and cerebral ischemia.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Cerebral Infarction; Dizocilpine Maleate; Ischemic Attack, Transient; Male; Mice; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Vasodilator Agents | 1994 |
The effect of hemorrhagic hypotension and retransfusion and 7-nitro-indazole on rCBF, NOS catalytic activity, and cortical NO content in the cat.
Topics: Acetylcholine; Adenosine Triphosphate; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Blood Pressure; Blood Transfusion; Brain; Cats; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Electroencephalography; Hemorrhage; Hypotension; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Organ Specificity; Parietal Lobe; Pituitary Gland; Regional Blood Flow; Spinal Cord; Vasodilator Agents | 1994 |
Effects of a nitric oxide donor on glutamate and GABA release in striatum and hippocampus of the conscious rat.
Topics: Amino Acid Oxidoreductases; Animals; Antihypertensive Agents; Arginine; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Molsidomine; Neostriatum; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Spectrometry, Fluorescence | 1994 |
Influence of nitric oxide synthase inhibition, nitric oxide and hydroperoxide on insulin release induced by various secretagogues.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Oxidoreductases; Animals; Arginine; Colforsin; Cyclic AMP; Cyclic GMP; Female; Glucose; Hydrogen Peroxide; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Insulin; Islets of Langerhans; Mice; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxides; Reactive Oxygen Species; tert-Butylhydroperoxide; Vasodilator Agents | 1995 |
Modulation by nitric oxide of prostaglandin biosynthesis in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Amino Acid Oxidoreductases; Animals; Arachidonic Acid; Arginine; Capillary Permeability; Edema; Epoprostenol; Lipopolysaccharides; Male; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Vasodilator Agents | 1995 |
The role of free radicals in NMDA-dependent neurotoxicity.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcium; Cells, Cultured; Cerebellar Cortex; Cyclic GMP; Electron Spin Resonance Spectroscopy; Enzyme Activation; Epilepsy; Feedback; Free Radicals; Glutamic Acid; Guanylate Cyclase; Kindling, Neurologic; Mice; Molsidomine; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Receptors, N-Methyl-D-Aspartate | 1994 |
Reciprocal modulation of aconitase activity and RNA-binding activity of iron regulatory factor by nitric oxide.
Topics: Aconitate Hydratase; Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Interferon-gamma; Iron-Regulatory Proteins; Leukemia P388; Lipopolysaccharides; Macrophages; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Recombinant Proteins; RNA-Binding Proteins; RNA, Messenger; Tumor Cells, Cultured; Vasodilator Agents | 1994 |
Streptokinase-prostacyclin--nitric oxide: in vivo interactions.
Topics: Animals; Arginine; Aspirin; Blood Pressure; Cats; Epoprostenol; Extracorporeal Circulation; Fibrinolysis; Heparitin Sulfate; Iloprost; Infusions, Intravenous; Injections, Intravenous; Molsidomine; Nitric Oxide; Nitroarginine; Platelet Aggregation; Streptokinase; Thrombosis; Vasodilator Agents | 1995 |
NG-nitro-L-arginine protects against hypoxia/hypoglycemia-induced decrease in CA1 presynaptic spikes in rat hippocampal slices.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Electrophysiology; Hippocampus; Hypoglycemia; Hypoxia, Brain; In Vitro Techniques; Male; Molsidomine; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Receptors, Presynaptic; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Role of cyclic nucleotides and nitric oxide in blood mononuclear cell IgE production stimulated by IL-4.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Arginine; B-Lymphocytes; Cholera Toxin; Cyclic AMP; Cyclic GMP; Drug Synergism; Epinephrine; Gene Expression Regulation; Humans; Immunoglobulin E; Interleukin-4; Leukocytes, Mononuclear; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Receptors, IgE; Recombinant Fusion Proteins | 1995 |
Distribution of human i-NANC bronchodilator and nitric oxide-immunoreactive nerves.
Topics: Adolescent; Adult; Amino Acid Oxidoreductases; Arginine; Autonomic Nervous System; Bronchi; Bronchoconstriction; Child; Electrophysiology; Female; Humans; Male; Middle Aged; Molsidomine; Muscle, Smooth; Neural Inhibition; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Papaverine; Tetrodotoxin; Trachea; Vasodilator Agents | 1995 |
Pharmacological evidence that nitric oxide can act as an endogenous antipyretic factor in endotoxin-induced fever in rabbits.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Body Temperature Regulation; Brain; Fever; Injections, Intraventricular; Isosorbide Dinitrate; Lipopolysaccharides; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits; Salmonella typhi | 1995 |
Nitric oxide-mediated inactivation of mammalian ferrochelatase in vivo and in vitro: possible involvement of the iron-sulphur cluster of the enzyme.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Line; Cloning, Molecular; Enzyme Inhibitors; Escherichia coli; Ferrochelatase; Humans; Immunoblotting; Interferon-gamma; Iron-Sulfur Proteins; Lipopolysaccharides; Macrophages; Mammals; Mice; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Evidence for the role of nitric oxide in the circulation of the dental pulp.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Cats; Cuspid; Dental Pulp; Enzyme Inhibitors; Heart Rate; Homeostasis; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen; Regional Blood Flow; Vascular Resistance; Vasodilator Agents | 1995 |
Dissimilarity between prostaglandin E1 and nitric oxide donors as potentiators of plasma exudation in the rabbit skin in vivo.
Topics: Alprostadil; Animals; Arginine; Bradykinin; Capillary Permeability; Edema; Exudates and Transudates; Histamine; Histamine Antagonists; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Nitroprusside; Rabbits; Skin; Vasodilator Agents | 1995 |
Evidence for the involvement of cGMP in neural bronchodilator responses in humal trachea.
Topics: Adenosine Monophosphate; Adolescent; Adult; Arginine; Bronchoconstriction; Child; Chymotrypsin; Cyclic GMP; Electric Conductivity; Epithelium; Female; Humans; Male; Methylene Blue; Middle Aged; Molsidomine; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Tetrodotoxin; Time Factors; Trachea; Vasoactive Intestinal Peptide; Vasodilator Agents | 1995 |
Potentiation of the hyporeactivity induced by in vivo endothelial injury in the rat carotid artery by chronic treatment with fish oil.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Body Weight; Carotid Arteries; Carotid Artery Injuries; Catheterization; Cyclic GMP; Endothelium, Vascular; Fatty Acids; Fish Oils; Indomethacin; Isometric Contraction; Male; Methylene Blue; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Phenylephrine; Rats; Rats, Wistar; Superoxide Dismutase; Vascular Resistance; Vasodilator Agents | 1995 |
Interleukin-1 beta effects on cyclic GMP and cyclic AMP in cultured rat islets of Langerhans-arginine-dependence and relationship to insulin secretion.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Antihypertensive Agents; Arginine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Kinetics; Molsidomine; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley | 1993 |
Nitric oxide modulates the release of vasopressin from rat hypothalamic explants.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arginine Vasopressin; Hypothalamus; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Potassium Chloride; Rats; Rats, Wistar | 1993 |
Exogenous and endogenous nitric oxide attenuates tumor necrosis factor synthesis in the murine macrophage cell line RAW 264.7.
Topics: Animals; Arginine; Cell Line; Dose-Response Relationship, Drug; In Vitro Techniques; Macrophages; Mice; Molsidomine; Nitric Oxide; Time Factors; Tumor Necrosis Factor-alpha | 1995 |
Effects of NO-donors, SIN-1 and GEA 3175 on prostacyclin and cGMP synthesis in cultured rat endothelial cells.
Topics: Animals; Arginine; Calcimycin; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Female; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Triazoles | 1995 |
Effect of modifying nitric oxide pathway on liver circulation in a rabbit endotoxin shock model.
Topics: Animals; Arginine; Blood Flow Velocity; Blood Pressure; Hepatic Artery; Liver Circulation; Male; Mesenteric Arteries; Molsidomine; Nitric Oxide; Nitroarginine; Portal Vein; Rabbits; Shock, Septic; Vasodilator Agents | 1994 |
Increased nitric oxide synthesis during the development of endotoxin tolerance.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Arachidonic Acids; Arginine; Cells, Cultured; Drug Tolerance; Endotoxins; Lethal Dose 50; Lipopolysaccharides; Macrophages, Peritoneal; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Rats; Reference Values; Salmonella enteritidis | 1995 |
Cultured endothelial cells restore vasodilator responses to coronary arteries with impaired endothelial function and alter the response to a nitric oxide donor.
Topics: Animals; Arginine; Blood Flow Velocity; Calcimycin; Cells, Cultured; Coronary Circulation; Coronary Disease; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Umbilical Veins; Vasodilator Agents | 1994 |
Influence of SIN-1 and sodium nitroprusside (NANP) on ox-LDL metabolism in macrophages.
Topics: Animals; Arginine; Lipoproteins, LDL; Macrophages; Molsidomine; Nitric Oxide; Nitroarginine; Nitroprusside; Oxidation-Reduction; Rats; Rats, Wistar | 1994 |
Regulatory role of nitric oxide in the IL-4-induced IgE production by normal human peripheral blood mononuclear cells.
Topics: Arginine; Humans; Immunoglobulin E; In Vitro Techniques; Interleukin-4; Leukocytes, Mononuclear; Molsidomine; Nitric Oxide; Nitrites; omega-N-Methylarginine; Oxidants; Receptors, IgE | 1994 |
cGMP mediates the desensitization to bradykinin in isolated canine coronary arteries.
Topics: Animals; Arginine; Arteries; Bradykinin; Coronary Vessels; Cyclic GMP; Dogs; Drug Resistance; In Vitro Techniques; Methylene Blue; Molsidomine; Nitroarginine; Oxyhemoglobins; Potassium; Vasodilation; Vasodilator Agents | 1995 |
Nitric oxide has no chronotropic effect in right atria isolated from rat heart.
Topics: Acetylcholine; Aminoquinolines; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Guanylate Cyclase; Heart Atria; Heart Rate; In Vitro Techniques; Male; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Norepinephrine; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasodilator Agents | 1994 |
Involvement of Fc epsilon RII/CD23 and L-arginine-dependent pathway in IgE-mediated stimulation of human monocyte functions.
Topics: Arginine; Cells, Cultured; Cytokines; Humans; Immunoglobulin E; Molsidomine; Monocytes; Nitric Oxide; omega-N-Methylarginine; Receptors, IgE; Signal Transduction; Superoxides; Thromboxane B2 | 1994 |
Altered nitric oxide production and exogenous nitric oxide do not affect the proliferation of rat mesangial cells.
Topics: Animals; Arginine; Cell Division; Cells, Cultured; Cyclic GMP; Glomerular Mesangium; Interleukin-1; Lipopolysaccharides; Molsidomine; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley | 1994 |
Involvement of Fc epsilon RII/CD23 and L-arginine dependent pathway in IgE-mediated activation of human eosinophils.
Topics: Antibodies, Monoclonal; Antihypertensive Agents; Arginine; Bone Marrow Cells; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Eosinophils; Hematopoietic Stem Cells; Humans; Immunoglobulin E; Kinetics; Molsidomine; omega-N-Methylarginine; Peroxides; Receptors, IgE; Superoxides; Tumor Necrosis Factor-alpha | 1994 |
Ischemic preconditioning protects against coronary endothelial dysfunction induced by ischemia and reperfusion.
Topics: Acetylcholine; Animals; Arginine; Calcimycin; Coronary Vessels; Endothelium, Vascular; Male; Molsidomine; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Serotonin; Vasodilator Agents | 1994 |
Long-term administration of L-arginine, L-NAME, and the exogenous NO donor molsidomine modulates urinary nitrate and cGMP excretion in rats.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Cholesterol; Chromatography, Gas; Cyclic GMP; Heart; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Time Factors | 1994 |
Stimulatory and inhibitory action of nitric oxide donor agents vs. nitrovasodilators on reactive oxygen production by isolated polymorphonuclear leukocytes.
Topics: Animals; Arginine; Dogs; Free Radical Scavengers; Luminescent Measurements; Luminol; Molsidomine; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Reactive Oxygen Species; Vasodilator Agents | 1994 |
Alterations in coronary artery vascular reactivity of hypertensive Ren-2 transgenic rats.
Topics: Acetylcholine; Animals; Animals, Genetically Modified; Arginine; Coronary Vessels; Endothelium, Vascular; Hypertension; In Vitro Techniques; Molsidomine; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 1994 |
The opposing effects of an inhibitor of nitric oxide synthesis and of a donor of nitric oxide in rabbits undergoing myocardial ischemia reperfusion.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Heart; Molsidomine; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Necrosis; Nitric Oxide; Nitroarginine; Rabbits; Reference Values; Vasodilator Agents | 1994 |
Differential sensitivity of proximal and distal coronary arteries to a nitric oxide donor following reperfusion injury or inhibition of nitric oxide synthesis.
Topics: Animals; Arginine; Coronary Vessels; Culture Techniques; Depression, Chemical; Dogs; Female; Male; Molsidomine; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Vasoconstriction; Vasodilation; Vasodilator Agents | 1993 |
Nitric oxide-induced microvascular permeability alterations: a regulatory role for cGMP.
Topics: Animals; Arginine; Atrial Natriuretic Factor; Capillary Permeability; Cats; Cyclic GMP; Intestines; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Regional Blood Flow | 1993 |
Local anesthetic drugs reduce endothelium-dependent relaxations of porcine ciliary arteries.
Topics: Anesthetics, Local; Animals; Arginine; Arteries; Ciliary Body; Endothelium, Vascular; Isometric Contraction; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Swine; Vasodilator Agents | 1993 |
Endothelial L-arginine pathway and relaxations to vasopressin in canine basilar artery.
Topics: Animals; Arginine; Basilar Artery; Cyclic GMP; Dogs; Endothelium, Vascular; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitroarginine; Vasodilation; Vasopressins | 1993 |
Nitric oxide modulates the release of corticotropin-releasing hormone from the rat hypothalamus in vitro.
Topics: Animals; Arginine; Basal Metabolism; Corticotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Interleukin-1; Male; Molsidomine; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Potassium Chloride; Rats; Rats, Wistar | 1993 |
Modification of energy metabolism and radiation response of a murine tumour by changes in nitric oxide availability.
Topics: Animals; Arginine; Biological Availability; Cell Hypoxia; Energy Metabolism; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C3H; Molsidomine; Neoplasm Transplantation; Neoplasms, Experimental; Nitric Oxide; Nitroarginine; Radiation Tolerance | 1993 |
Hyporesponsiveness to nitrovasodilators in rat aorta incubated with endotoxin and L-arginine.
Topics: Animals; Aorta; Arginine; Dose-Response Relationship, Drug; Drug Tolerance; Endotoxins; Male; Molsidomine; Nitroprusside; Rats; Rats, Wistar; Vasodilator Agents | 1995 |
Intestinal absorption of calcium in vivo is dependent on endogenous nitric oxide.
Topics: Animals; Arginine; Calcium; Female; Intestinal Absorption; Intestine, Small; Male; Mesenteric Veins; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Penicillamine; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1995 |
Myocardial and coronary endothelial protective effects of acetylcholine after myocardial ischaemia and reperfusion in rats: role of nitric oxide.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Male; Molsidomine; Myocardial Infarction; Myocardial Ischemia; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Potassium Channel Blockers; Rats; Rats, Wistar; Vasodilator Agents | 1995 |
Mediation by prostaglandins of the nitric oxide-induced neurogenic vasodilatation in rat skin.
Topics: Animals; Arginine; Bradykinin; Calcitonin Gene-Related Peptide; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Histamine; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Prostaglandins; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Skin; Skin Physiological Phenomena; Vasodilation; Vasodilator Agents | 1995 |
Nitric oxide mediates the anti-adrenergic effect of adenosine on calcium current in isolated rabbit atrioventricular nodal cells.
Topics: Adenosine; Adrenergic Antagonists; Animals; Arginine; Atrioventricular Node; Calcium Channels; Isoproterenol; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Rabbits; Xanthines | 1996 |
Nitric oxide-dependent blood-brain barrier permeability alteration in the rat brain.
Topics: Animals; Arginine; Atropine; Blood Pressure; Blood-Brain Barrier; Heart Rate; Kinetics; Microcirculation; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Permeability; Rats; Rats, Sprague-Dawley; Reference Values; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1996 |
A possible role for nitric oxide but not for prostaglandin E2 in basal and interleukin-1-beta-induced PRL release in vitro.
Topics: Animals; Arginine; Cells, Cultured; Dinoprostone; Hemoglobins; Hypothalamus; Interleukin-1; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar | 1995 |
Nitric oxide synthase (NOS3)-mediated cholinergic modulation of Ca2+ current in adult rabbit atrioventricular nodal cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Action Potentials; Animals; Arginine; Atrioventricular Node; Calcium Channels; Carbachol; Cyclic GMP; Immunohistochemistry; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Receptors, Muscarinic | 1996 |
Role of nitric oxide and phosphodiesterase isoenzyme II for reduction of endothelial hyperpermeability.
Topics: Animals; Arginine; Cell Membrane Permeability; Cells, Cultured; Electric Conductivity; Endothelium, Vascular; Enzyme Inhibitors; Escherichia coli; Hemolysin Proteins; Hydrogen Peroxide; Isoenzymes; Kinetics; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroglycerin; Nitroprusside; Phosphoric Diester Hydrolases; Pulmonary Artery; Swine | 1996 |
Increased guanylate cyclase activity is associated with an increase in cyclic guanosine 3',5'-monophosphate in left ventricular hypertrophy.
Topics: Animals; Arginine; Cyclic GMP; Dogs; Female; Guanylate Cyclase; Hypertrophy, Left Ventricular; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Oxygen Consumption | 1996 |
Regulation of VIP release from rat enteric nerve terminals: evidence for a stimulatory effect of NO.
Topics: Animals; Arginine; Calcium; Cell Fractionation; Cyclic GMP; Intestine, Small; Membrane Potentials; Molsidomine; NADPH Dehydrogenase; Nerve Endings; Nitric Oxide; Nitroprusside; Protein Kinase C; Rats; Rats, Wistar; Synaptosomes; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1996 |
L-arginine is unlikely to exert neuroendocrine effects in humans via the generation of nitric oxide.
Topics: Adrenocorticotropic Hormone; Adult; Arginine; Blood Glucose; Drug Synergism; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Male; Molsidomine; Neurosecretory Systems; Nitric Oxide; Vasodilator Agents; Vasopressins | 1996 |
Prophylactic administration of L-arginine improves the intestinal barrier function after mesenteric ischaemia.
Topics: Amino Acids, Essential; Analysis of Variance; Animals; Arginine; Cyclic GMP; Intestinal Mucosa; Male; Mesenteric Arteries; Molsidomine; Nitric Oxide Synthase; Permeability; Polyethylene Glycols; Rats; Rats, Wistar; Reperfusion Injury; Survival Rate; Treatment Outcome; Vasodilator Agents | 1996 |
L-arginine reduces human monocyte adhesion to vascular endothelium and endothelial expression of cell adhesion molecules.
Topics: Arginine; Blotting, Northern; Cell Adhesion; Cells, Cultured; Drug Combinations; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Molsidomine; Monocytes; omega-N-Methylarginine; Vascular Cell Adhesion Molecule-1 | 1997 |
Mechanisms of arginine-induced increase in cytosolic calcium concentration in the beta-cell line NIT-1.
Topics: Animals; Arginine; Calcium; Cell Line; Cytosol; Diazoxide; Homoarginine; Insulin; Insulin Secretion; Insulinoma; Kinetics; Mice; Mice, Transgenic; Molsidomine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pancreatic Neoplasms; Potassium Channels; Potassium Chloride; Tumor Cells, Cultured; Verapamil | 1997 |
Opposite effects of nitric oxide on identified inhibitory and excitatory cholinergic synapses of Aplysia californica.
Topics: Acetylcholine; Action Potentials; Animals; Aplysia; Arginine; Calcium Channels; Cholinergic Agonists; Cholinergic Antagonists; Cyclic GMP; Ganglia, Invertebrate; Ganglia, Parasympathetic; Guanylate Cyclase; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels; Synapses; Synaptic Transmission | 1996 |
NO-mediated vasodilation in the rat liver. Role of hepatocytes and liver endothelial cells.
Topics: Animals; Arginine; Cells, Cultured; Cytokines; Endothelium, Vascular; Guanylate Cyclase; Liver; Liver Circulation; Male; Methylene Blue; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasodilation | 1997 |
Interleukin 1beta-mediated inhibition of arginase in RINm5F cells.
Topics: Animals; Arginase; Arginine; Citrulline; Enzyme Inhibitors; Glutathione; Insulinoma; Interleukin-1; Islets of Langerhans; Molsidomine; Nitric Oxide Synthase; Nitroso Compounds; Ornithine; Rats; S-Nitrosoglutathione; Tumor Cells, Cultured | 1997 |
Hypoxia compared with normoxia alters the effects of nitric oxide in ischemia-reperfusion lung injury.
Topics: Animals; Arginine; Blood Pressure; Hypoxia; In Vitro Techniques; Lung; Male; Microcirculation; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Artery; Pulmonary Circulation; Rabbits; Reperfusion Injury; Stereoisomerism; Superoxide Dismutase; Vascular Resistance | 1997 |
The effects of L-arginine on neointimal formation and vascular function following balloon injury in heritable hyperlipidaemic rabbits.
Topics: Angioplasty, Balloon; Animals; Arginine; Calcimycin; Carbachol; Endothelium, Vascular; Hyperlipidemias; In Vitro Techniques; Male; Molsidomine; Muscle, Smooth, Vascular; Platelet Aggregation; Platelet Aggregation Inhibitors; Potassium Chloride; Rabbits; Serotonin; Tunica Intima; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
Possible role of nitric oxide in IgE-mediated allergic cutaneous reaction in mice.
Topics: Animals; Arginine; Dinitrofluorobenzene; Dinitrophenols; Edema; Female; Immunization, Passive; Immunoglobulin E; Interleukin-1; Mice; Mice, Inbred BALB C; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Tumor Necrosis Factor-alpha; Vasculitis, Leukocytoclastic, Cutaneous | 1998 |
Nitric oxide donors antagonize N-nitro-L-arginine and haloperidol catalepsy: potential implication for the treatment of Parkinsonism?
Topics: Animals; Arginine; Catalepsy; Disease Models, Animal; Haloperidol; Male; Molsidomine; Nitric Oxide Synthase; Nitroarginine; Parkinson Disease; Rats; Rats, Wistar; Vasodilator Agents | 1997 |
Role of nitric oxide synthase inhibition in the acute hypertensive response to intracerebroventricular cadmium.
Topics: Animals; Arginine; Blood Pressure; Brain Chemistry; Cadmium; Calcium Chloride; Citrulline; Enzyme Inhibitors; Heart Rate; Hypertension; Injections, Intraventricular; Male; Molsidomine; Nitric Oxide Synthase; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1998 |
Endogenous nitric oxide in the rat pons promotes sleep.
Topics: Anilides; Animals; Arginine; Behavior, Animal; Male; Microinjections; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pons; Rats; Rats, Wistar; Sleep; Tegmentum Mesencephali; Time Factors; Wakefulness | 1999 |
The neuromuscular transmission fade (Wedensky inhibition) induced by L-arginine in neuromuscular preparations from rats.
Topics: Animals; Arginine; Diaphragm; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Molsidomine; Muscle Contraction; Muscle, Skeletal; Neuromuscular Junction; Nitroarginine; Oxadiazoles; Phrenic Nerve; Quinoxalines; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Nitric oxide synthase inhibitors enhance 5-HT2 receptor-mediated behavior, the head-twitch response in mice.
Topics: Animals; Arginine; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Head Movements; Male; Methylene Blue; Mice; Mice, Inbred ICR; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Penicillamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1999 |
Nitric oxide and l-arginine cause an accumulation of utrophin at the sarcolemma: a possible compensation for dystrophin loss in Duchenne muscular dystrophy.
Topics: Animals; Arginine; Cell Line; Cytoskeletal Proteins; Dystrophin; Hydroxyurea; Membrane Proteins; Mice; Mice, Inbred C57BL; Molsidomine; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nitric Oxide; Nitric Oxide Donors; Utrophin | 1999 |
Decreased synthesis and vasodilation to nitric oxide in piglets with hypoxia-induced pulmonary hypertension.
Topics: Animals; Animals, Newborn; Arginine; Blood Vessels; Cyclic GMP; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pulmonary Circulation; Swine; Vasodilation; Vasodilator Agents | 2000 |
Citrulline does not relax isolated rat and rabbit vessels.
Topics: Animals; Aorta, Thoracic; Arginine; Carotid Arteries; Citrulline; Dose-Response Relationship, Drug; Female; Femoral Artery; In Vitro Techniques; Male; Molsidomine; Nitric Oxide Donors; Norepinephrine; Rabbits; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2000 |
Endothelium-dependent relaxation of small resistance vessels is impaired in patients with autosomal dominant polycystic kidney disease.
Topics: Acetylcholine; Adult; Arginine; Blood Vessels; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Male; Microcirculation; Middle Aged; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Polycystic Kidney, Autosomal Dominant; Reference Values; Skin; Vascular Resistance; Vasodilation | 2000 |
Nitric oxide-induced cGMP accumulation in the mouse bladder is not related to smooth muscle relaxation.
Topics: Animals; Arginine; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Mice; Mice, Inbred BALB C; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phosphodiesterase Inhibitors; Piperazines; Piperidines; Purines; Quinazolines; Sildenafil Citrate; Sulfones; Urethra; Urinary Bladder | 2000 |
L-arginine application improves graft morphology and mucosal barrier function after small bowel transplantation.
Topics: Animals; Arginine; Biomarkers; Hyaluronan Receptors; Hyaluronic Acid; Interleukin-1; Interleukin-6; Intestinal Mucosa; Intestine, Small; Laminin; Male; Methylprednisolone; Molsidomine; Organ Preservation; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous; Transplantation, Isogeneic; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2000 |
Guanylate cyclase and not ATP-dependent K(+) channels seems temperature-dependent in smooth muscle relaxation of human umbilical arteries.
Topics: Adenosine Triphosphate; Arginine; Cromakalim; Dose-Response Relationship, Drug; Female; Glyburide; Guanylate Cyclase; Humans; In Vitro Techniques; Molsidomine; Muscle, Smooth, Vascular; Nicorandil; Nitroarginine; Oxadiazoles; Potassium Channels; Pregnancy; Quinoxalines; Serotonin; Temperature; Umbilical Arteries; Vasodilation; Vasodilator Agents | 2000 |
Modulatory effects of nitric oxide on synaptic depression in the crayfish neuromuscular system.
Topics: Animals; Arginine; Astacoidea; Benzoates; Enzyme Inhibitors; Female; Glutamic Acid; Hydrazines; Imidazoles; Male; Molsidomine; Motor Neurons; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Superoxide Dismutase; Synaptic Transmission | 2000 |
Nitric oxide limits pressor responses to sympathetic activation in rat spinal cord.
Topics: Anesthesia; Animals; Arginine; Calcium; Enzyme Activation; Enzyme Inhibitors; Male; Molsidomine; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Pressoreceptors; Rats; Rats, Inbred WKY; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Sympathetic Nervous System | 2000 |
Inhibition of nitric oxide synthase activity reduces liver injury in murine schistosomiasis.
Topics: Animals; Arginine; Enzyme Inhibitors; Female; Hydroxyproline; Lipid Peroxides; Liver; Liver Cirrhosis; Lung; Mice; Mice, Inbred CBA; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Parasite Egg Count; Rodent Diseases; Schistosomiasis | 2001 |
Nitric oxide modulates cardiac performance in the heart of Anguilla anguilla.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Anguilla; Animals; Arginine; Atropine; Detergents; Enzyme Inhibitors; Female; Free Radical Scavengers; Heart; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Molsidomine; Muscarinic Antagonists; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Octoxynol; omega-N-Methylarginine; Ornithine; Oxadiazoles; Parasympatholytics; Pirenzepine; Quinoxalines; Superoxide Dismutase | 2001 |
[Inhibition of signal transduction pathways of endothelin-1-induced proliferation of vascular smooth muscle cells by nitric oxide].
Topics: Animals; Aorta, Thoracic; Arginine; Cell Division; Cells, Cultured; Endothelin-1; Mitogen-Activated Protein Kinases; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Protein Kinase C; Rabbits; Signal Transduction | 1998 |
Comparative trial of local pharmacotherapy with L-arginine, r-hirudin, and molsidomine to reduce restenosis after balloon angioplasty of stenotic rabbit iliac arteries.
Topics: Administration, Topical; Angioplasty, Balloon; Animals; Antithrombins; Arginine; Constriction, Pathologic; Hirudin Therapy; Hirudins; Iliac Artery; Male; Molsidomine; Nitric Oxide Donors; Rabbits; Recurrence; Vasodilator Agents | 2001 |
Role of nitric oxide in histamine release from human basophils and rat peritoneal mast cells.
Topics: Animals; Antibodies; Arginine; Basophils; Calcimycin; Dose-Response Relationship, Drug; Guanidines; Hemoglobins; Histamine; Humans; Immunoglobulin E; Male; Mast Cells; Methylene Blue; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nitroprusside; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Rats; Rats, Sprague-Dawley; Sodium Fluoride; Sodium Nitrite | 2001 |
Nitric oxide-cGMP-mediated vasoconstriction and effects of acetylcholine in the branchial circulation of the eel.
Topics: Acetylcholine; Animals; Arginine; Branchial Region; Cyclic GMP; Dose-Response Relationship, Drug; Eels; Endothelium, Vascular; Female; Gills; Hemoglobins; In Vitro Techniques; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Vasoconstriction | 2002 |
The combined treatment with L-arginine and methylprednisolone improves graft morphology and mucosal barrier function.
Topics: Animals; Arginine; Graft Survival; Intestinal Mucosa; Intestine, Small; Methylprednisolone; Molsidomine; Rats; Rats, Inbred Lew; Reperfusion Injury; Transplantation, Isogeneic; Vasodilator Agents | 2002 |
[Exogenous nitric oxide and gallbladder contractility in humans].
Topics: Administration, Oral; Administration, Sublingual; Adult; Arginine; Female; Gallbladder; Gallbladder Emptying; Humans; Infusions, Intravenous; Male; Molsidomine; Nitric Oxide Donors; Nitroglycerin; Reference Values; Time Factors | 2002 |
Inhibition of arginine synthesis by urea: a mechanism for arginine deficiency in renal failure which leads to increased hydroxyl radical generation.
Topics: Animals; Arginine; Cells, Cultured; Dose-Response Relationship, Drug; Guanidines; Hepatocytes; Hydroxyl Radical; Male; Models, Biological; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Ornithine; Oxygen; Rats; Rats, Wistar; Reactive Oxygen Species; Renal Insufficiency; Succinates; Urea | 2003 |
Opposite nociceptive effects of the arginine/NO/cGMP pathway stimulation in dermal and subcutaneous tissues.
Topics: Animals; Arginine; Bucladesine; Cyclic GMP; Dermis; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Subcutaneous; Male; Molsidomine; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Subcutaneous Tissue; Time Factors | 2003 |
Behavioral effects of NMDA receptor agonists and antagonists in combination with nitric oxide-related compounds.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Gallic Acid; Guanidines; Indazoles; Injections, Intraperitoneal; Kynurenic Acid; Molsidomine; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2003 |
NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Enzyme Inhibitors; Fibronectins; Fibrosis; Gene Expression; Glomerulonephritis; Isoantibodies; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Plasminogen Activator Inhibitor 1; Proteinuria; Rats; Rats, Wistar; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
The role of nitric oxide in systemic and hepatic haemodynamics in the rat in vivo.
Topics: Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Hepatic Artery; Liver Circulation; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Portal Vein; Rats; Rats, Wistar | 2003 |
[L-arginine administration improves mucosal structure in the early phase of reperfusion of small intestine transplants].
Topics: Animals; Anti-Inflammatory Agents; Arginine; Drug Therapy, Combination; Intestinal Mucosa; Intestine, Small; Methylprednisolone; Molsidomine; Premedication; Rats; Rats, Inbred Lew; Reperfusion Injury; Vasodilator Agents | 1998 |
Reduction in [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced peripheral antinociception in diabetic rats: the role of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway.
Topics: Analgesics, Opioid; Animals; Arginine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Formaldehyde; Guanylate Cyclase; Male; Methylene Blue; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Pain; Pain Measurement; Rats; Rats, Wistar | 2004 |
Differential antinociceptive effects of L-arginine and 3-morpholinosydoimine.
Topics: Analgesics; Animals; Arginine; Dose-Response Relationship, Drug; Dynorphins; Injections, Intraventricular; Male; Mice; Molsidomine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement | 2003 |
Participation of the NO-cyclic GMP pathway in rofecoxib-induced antinociception.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Isoenzymes; Lactones; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxadiazoles; Pain; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Rats; Rats, Wistar; Sulfones; Uric Acid | 2003 |
Microinjection of the nitric oxide synthase inhibitor L-NAME into the lateral basal forebrain alters the sleep/wake cycle of the rat.
Topics: Acetylcholine; Adenosine; Analysis of Variance; Animals; Arginine; Behavior, Animal; Diagonal Band of Broca; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; gamma-Aminobutyric Acid; Male; Microinjections; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Prosencephalon; Rats; Rats, Wistar; Sleep; Time Factors; Wakefulness | 2004 |
Effects of phosphodiesterase V inhibition on nitric oxide-mediated relaxation responses in guinea pig trachea.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Electric Stimulation; Electrodes; Guinea Pigs; Histamine; Isomerism; Male; Molsidomine; Muscle Relaxation; Muscle, Smooth; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Trachea | 2004 |
Endothelium-dependent relaxation of canine pulmonary artery after prolonged lung graft preservation in University of Wisconsin solution: role of L-arginine supplementation.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Allopurinol; Animals; Arginine; Dogs; Endothelium, Vascular; Female; Glutathione; Insulin; Lung; Lung Transplantation; Male; Molsidomine; omega-N-Methylarginine; Organ Preservation Solutions; Pulmonary Artery; Raffinose; Sodium Fluoride; Tissue Preservation | 2004 |
Effects of L-arginine and SIN-1 on sleep and waking in the rat during both phases of the light-dark cycle.
Topics: Analysis of Variance; Animals; Arginine; Central Nervous System; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Male; Molsidomine; Nitric Oxide; Photoperiod; Rats; Sleep; Time Factors | 2004 |
No hemoglobin but NO: the icefish (Chionodraco hamatus) heart as a paradigm.
Topics: Animals; Antarctic Regions; Arginine; Cardiotonic Agents; Cell Respiration; Cyclic GMP; Electrochemistry; Fluorescent Antibody Technique; Molsidomine; Myocardial Contraction; Myocardium; NADH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oceans and Seas; Ornithine; Perciformes | 2004 |
Effect of molsidomine and L-arginine in cyclosporine nephrotoxicity: role of nitric oxide.
Topics: Administration, Oral; Animals; Arginine; Cyclosporine; Dose-Response Relationship, Drug; Drinking; Drug Therapy, Combination; Enzyme Inhibitors; Immunosuppressive Agents; Injections, Subcutaneous; Kidney Diseases; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Rats; Water Supply | 2005 |
Molsidomine, a nitric oxide donor and L-arginine protects against rhabdomyolysis-induced myoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Animals; Arginine; Glycerol; Kidney; Male; Molsidomine; Myoglobinuria; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Rats; Rats, Wistar; Rhabdomyolysis | 2005 |
Renal protective effect of molsidomine and L-arginine in ischemia-reperfusion induced injury in rats.
Topics: Animals; Arginine; Kidney; Kidney Diseases; Male; Models, Animal; Molsidomine; Nephrectomy; Nitric Oxide Donors; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2005 |
Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects.
Topics: Animals; Antidepressive Agents; Arginine; Dose-Response Relationship, Drug; Hippocampus; Imipramine; Indazoles; Male; Molsidomine; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Rats; Rats, Wistar | 2006 |
Dynorphin-mediated antinociceptive effects of L-arginine and SIN-1 (an NO donor) in mice.
Topics: Analgesics; Animals; Arginine; Brain; Dynorphins; Enzyme Inhibitors; Injections, Intraventricular; Male; Mice; Molsidomine; Naloxone; Narcotic Antagonists; Nitric Oxide Donors; Pain Measurement | 2006 |
Nitric oxide modulates ionic transport in the isolated intestine of the eel, Anguilla anguilla.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Anguilla; Animals; Arginine; Bicarbonates; Chlorides; Cyclic GMP; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Intestinal Absorption; Intestinal Mucosa; Intestines; Membrane Potentials; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Permeability; Quinoxalines; Time Factors | 2007 |
Modulation of stress-induced neurobehavioral changes and brain oxidative injury by nitric oxide (NO) mimetics in rats.
Topics: Animals; Arginine; Behavior, Animal; Brain; Glutathione; Isosorbide Dinitrate; Lipid Peroxidation; Male; Maze Learning; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; Stress, Psychological | 2007 |
Nitric oxide modulates the frog heart ventricle morphodynamics.
Topics: Animals; Anura; Arginine; Cyclic GMP; Female; Heart Ventricles; In Vitro Techniques; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Perfusion; Serine; Software; Ventricular Function | 2008 |
Co-administration of nitric oxide (NO) donors prevents haloperidol-induced orofacial dyskinesia, oxidative damage and change in striatal dopamine levels.
Topics: Animals; Antipsychotic Agents; Arginine; Chromatography, High Pressure Liquid; Citrulline; Dopamine; Dyskinesia, Drug-Induced; Haloperidol; Male; Molsidomine; Movement Disorders; Neostriatum; Nitric Oxide Donors; Oxidative Stress; Rats; Rats, Wistar; Superoxides | 2009 |
Morphological and physiological study of the cardiac NOS/NO system in the Antarctic (Hb-/Mb-) icefish Chaenocephalus aceratus and in the red-blooded Trematomus bernacchii.
Topics: Animals; Antarctic Regions; Arginine; Blotting, Western; Cyclic GMP; Endocardium; Female; Fluorescent Antibody Technique; Heart Ventricles; Hemodynamics; Male; Molsidomine; Myocardium; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Perciformes; Signal Transduction; Stroke Volume | 2009 |
Arginase contributes to endothelial cell oxidative stress in response to plasma from women with preeclampsia.
Topics: Arginase; Arginine; Biopterins; Endothelial Cells; Female; Humans; Molsidomine; NADPH Oxidases; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Pre-Eclampsia; Pregnancy | 2010 |
Perinatal micronutrient supplements ameliorate hypertension and proteinuria in adult fawn-hooded hypertensive rats.
Topics: Animals; Arginine; Ascorbic Acid; Blood Pressure; Dietary Supplements; Female; Hypertension; Kidney Diseases; Male; Micronutrients; Molsidomine; Nitric Acid; Nitric Oxide Donors; Potassium; Proteinuria; Rats; Rats, Inbred Strains; Sex Factors; Sodium; Taurine; Vitamin E | 2010 |
Upregulation of neuronal nitric oxide synthase in the periphery promotes pain hypersensitivity after peripheral nerve injury.
Topics: Animals; Arginine; Hyperalgesia; Male; Molsidomine; Neuralgia; Nitric Oxide Synthase Type I; Pain Threshold; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Schwann Cells; Sensory Receptor Cells; Up-Regulation | 2011 |
Increasing the availability of l-arginine and nitric oxide increases sensitivity of nitrous oxide (N2O)-insensitive inbred mice to N2O-induced antinociception.
Topics: Abdominal Pain; Analgesics; Analysis of Variance; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitrous Oxide; Pain Threshold; Species Specificity | 2016 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |