moguisteine has been researched along with diphenhydramine hydrochloride in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (72.73) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnabè, R; Berni, F; Clini, V; Pirrelli, M; Pisani Ceretti, A; Robuschi, M; Rossi, M; Sestini, P; Tana, F; Vaghi, A | 1 |
| Cavalletti, E; Ceserani, R; Montaguti, P; Sala, F; Tognella, S | 1 |
| Bussi, R; Cavalletti, E; Ceserani, R; Montaguti, P; Tognella, S | 1 |
| Borghi, A; Dalla Rosa, C; Di Domenico, R; Fiocchi, L; Gallico, L; Gandolfi, CA; Lotto, A; Menta, E; Spinelli, S; Tognella, S | 1 |
| Borghi, A; Ceserani, R; Dalla Rosa, C; Gallico, L; Tognella, S | 1 |
| Allegra, L; Aversa, C; Cazzola, M; Clini, V; Dal Negro, R; Maiorano, V; Tana, F | 1 |
| Bernareggi, A; Castoldi, D; Oggioni, A | 1 |
| Bernareggi, A; Castoldi, D; Di Giovine, S; Oggioni, A; Ratti, E; Renoldi, MI | 1 |
| Borghi, A; Cavalletti, E; Ceserani, R; Gallico, L; Tognella, S | 1 |
| Ceserani, R; Dalla Rosa, C; Gallico, L; Oggioni, N; Tognella, S | 1 |
| Kamei, J; Morita, K | 2 |
| Cavalletti, E; Ceserani, R; Montaguti, P; Sala, F | 1 |
| Gallico, L; Morikawa, T; Widdicombe, J | 1 |
| Sant'Ambrogio, FB; Sant'Ambrogio, G | 1 |
| Kamei, J; Kashiwazaki, T; Morita, K; Ohsawa, M | 1 |
| Ceserani, R; Furuta, M; Gallico, L; Hashimoto, M; Ishii, R; Naruse, T | 1 |
| Kamei, J; Morita, K; Onodera, K | 1 |
| Chung, KF | 1 |
| Bu, F; Guo, R; Liu, X; Song, H; Teng, Y; Wang, B; Wei, C; Yuan, G; Zhang, R; Zhao, W | 1 |
| Li, PB; Luo, YL; Nie, YC; Su, WW; Wang, S; Zhang, CC; Zhang, KJ; Zheng, YF | 1 |
| Feng, P; Gou, ZP; Wang, Y; Xiang, J; Zheng, L | 1 |
1 review(s) available for moguisteine and diphenhydramine hydrochloride
| Article | Year |
|---|---|
Currently available cough suppressants for chronic cough.
Topics: Antitussive Agents; Central Nervous System; Chronic Disease; Codeine; Cough; Dextromethorphan; Humans; Morphine; Narcotics; Reflex; Thiazolidines; Treatment Outcome | 2008 |
3 trial(s) available for moguisteine and diphenhydramine hydrochloride
| Article | Year |
|---|---|
The efficacy and safety of moguisteine in comparison with codeine phosphate in patients with chronic cough.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antitussive Agents; Chronic Disease; Circadian Rhythm; Codeine; Cough; Double-Blind Method; Female; Humans; Lung Diseases, Obstructive; Lung Neoplasms; Male; Middle Aged; Pulmonary Fibrosis; Safety; Thiazoles; Thiazolidines | 1995 |
Clinical trial of the efficacy and safety of moguisteine in patients with cough associated with chronic respiratory diseases.
Topics: Adult; Aged; Antitussive Agents; Chronic Disease; Cough; Double-Blind Method; Female; Humans; Male; Middle Aged; Respiratory Tract Diseases; Thiazoles; Thiazolidines | 1993 |
Single- and multiple-dose pharmacokinetics of the peripheral non-narcotic antitussive moguisteine in healthy Chinese volunteers.
Topics: Adolescent; Adult; Antitussive Agents; Asian People; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Healthy Volunteers; Humans; Male; Middle Aged; Thiazolidines; Young Adult | 2019 |
18 other study(ies) available for moguisteine and diphenhydramine hydrochloride
| Article | Year |
|---|---|
General toxicology of the new antitussive moguisteine.
Topics: Animals; Antitussive Agents; Carcinogens; Dogs; Female; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Mutagens; Pregnancy; Rabbits; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1994 |
Reproductive toxicology of the new antitussive moguisteine.
Topics: Abnormalities, Drug-Induced; Animals; Antitussive Agents; Embryo, Mammalian; Female; Fertility; Growth; Labor, Obstetric; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Rats; Rats, Sprague-Dawley; Reproduction; Teratogens; Thiazoles; Thiazolidines; Weight Gain | 1994 |
N-acyl-2-substituted-1,3-thiazolidines, a new class of non-narcotic antitussive agents: studies leading to the discovery of ethyl 2-[(2-methoxyphenoxy)methyl]-beta-oxothiazolidine-3-propanoate.
Topics: Animals; Antitussive Agents; Drug Design; Guinea Pigs; Male; Rats; Thiazoles; Thiazolidines | 1995 |
Moguisteine: a novel peripheral non-narcotic antitussive drug.
Topics: Aerosols; Animals; Antitussive Agents; Binding, Competitive; Capsaicin; Citrates; Citric Acid; Codeine; Cough; Dogs; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Injections, Intraventricular; Male; Naloxone; Physical Stimulation; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Thiazoles; Thiazolidines | 1994 |
Direct HPLC separation of enantiomers of main moguisteine metabolite: comparison of different stationary phases.
Topics: Antitussive Agents; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Cyclodextrins; Indicators and Reagents; Orosomucoid; Solvents; Stereoisomerism; Thiazoles; Thiazolidines | 1994 |
Assay of moguisteine metabolites in human plasma and urine: conventional and chiral high-performance liquid chromatographic methods.
Topics: Antitussive Agents; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Kinetics; Methylene Chloride; Phosphoric Acids; Sensitivity and Specificity; Stereoisomerism; Thiazoles; Thiazolidines | 1994 |
Antitussive activity of moguisteine enantiomers in guinea-pigs and rats.
Topics: Administration, Oral; Aerosols; Animals; Antacids; Antitussive Agents; Capsaicin; Citric Acid; Cough; Dose-Response Relationship, Drug; Female; Guinea Pigs; Injections, Intraperitoneal; Lethal Dose 50; Male; Rats; Rats, Sprague-Dawley; Species Specificity; Stereoisomerism; Thiazoles; Thiazolidines | 1996 |
Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivo.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Antitussive Agents; Bronchial Hyperreactivity; Capsaicin; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Inflammation; Male; Regression Analysis; Respiratory System; Smoke; Thiazoles; Thiazolidines | 1996 |
Antitussive effect of moguisteine on the enhanced coughing associated with enalapril in guinea-pig.
Topics: Animals; Antitussive Agents; Capsaicin; Cough; Enalapril; Guinea Pigs; Male; Thiazoles; Thiazolidines | 1996 |
Comparative toxicology of two enantiomers of the peripherally acting non-narcotic antitussive drug moguisteine.
Topics: Administration, Oral; Animals; Antitussive Agents; Body Weight; Dogs; Female; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Mutagenicity Tests; Mutagens; Organ Size; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thiazoles; Thiazolidines | 1996 |
Actions of moguisteine on cough and pulmonary rapidly adapting receptor activity in the guinea pig.
Topics: Aerosols; Animals; Antitussive Agents; Binding Sites; Capsaicin; Cough; Dimethyl Sulfoxide; Female; Guinea Pigs; Lung; Male; Mechanoreceptors; Receptors, Cell Surface; Thiazoles; Thiazolidines | 1997 |
Action of moguisteine on the activity of tracheobronchial rapidly adapting receptors in the dog.
Topics: Adaptation, Physiological; Animals; Antitussive Agents; Bronchi; Dogs; Female; Male; Pulmonary Stretch Receptors; Thiazoles; Thiazolidines; Time Factors; Trachea | 1998 |
Antitussive effect of moguisteine on allergic coughs in the guinea pig.
Topics: Analgesics, Opioid; Animals; Antitussive Agents; Codeine; Cough; Disease Models, Animal; Guinea Pigs; Hypersensitivity; Male; Thiazoles; Thiazolidines | 1998 |
Effects of moguisteine on the cough reflex induced by afferent electrical stimulation of the superior laryngeal nerve in guinea pigs.
Topics: Aerosols; Animals; Anticoagulants; Antitussive Agents; Citric Acid; Codeine; Cough; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Injections, Intravenous; Injections, Intraventricular; Laryngeal Nerves; Reflex; Thiazoles; Thiazolidines | 1998 |
Involvement of ATP-sensitive K(+) channels in the anti-tussive effect of moguisteine.
Topics: Animals; Antitussive Agents; ATP-Binding Cassette Transporters; Cough; Disease Models, Animal; Drug Interactions; Glyburide; Guinea Pigs; KATP Channels; Male; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Thiazoles; Thiazolidines | 2000 |
Inhaled pinacidil, an ATP-sensitive K+ channel opener, and moguisteine have potent antitussive effects in guinea pigs.
Topics: Adenosine Triphosphate; Administration, Inhalation; Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Dose-Response Relationship, Drug; Drug Antagonism; Glyburide; Guinea Pigs; Male; Naloxone; Pinacidil; Potassium Channels; Thiazoles; Thiazolidines | 2002 |
Determination of the active metabolite of moguisteine in human plasma and urine by LC-ESI-MS method and its application in pharmacokinetic study.
Topics: Adult; Antitussive Agents; Chromatography, High Pressure Liquid; Female; Humans; Male; Random Allocation; Spectrometry, Mass, Electrospray Ionization; Thiazolidines; Young Adult | 2012 |
Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure.
Topics: Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Female; Flavanones; Guinea Pigs; Lung; Male; Neprilysin; Neurogenic Inflammation; Nicotiana; Propylene Glycols; Receptors, Neurokinin-1; Smoke; Substance P; Thiazolidines | 2013 |