mofezolac has been researched along with aspirin in 5 studies
*Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5) [MeSH]
*Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harada, S; Kakuta, H; Oda, H; Sasaki, K; Sugimoto, Y; Tai, A; Zheng, X | 1 |
| Boccarelli, A; Cabral, LM; de Pádula, M; Di Mauro, GD; Ferorelli, S; Fortuna, CG; Iaselli, M; Miciaccia, M; Pati, ML; Perrone, MG; Rodrigues Pereira da Silva, LC; Sathler, PC; Scilimati, A; Souza Domingos, TF; Vacca, A; Vitale, P | 1 |
| Araújo, CDCB; Bonaccorso, C; Cabral, LM; da Silva, LCRP; de Almeida, GS; de Pádula, M; Ferorelli, S; Fortuna, CG; Miciaccia, M; Perrone, MG; Sathler, PC; Scilimati, A; Souza Domingos, TF; Vitale, P | 1 |
| Bhardwaj, A; Kaur, J; Wuest, F | 1 |
| Amano, H; Hayashi, I; Inukai, M; Kamata, M; Kitasato, H; Majima, M; Yoshida, S; Yoshimura, H | 1 |
5 other study(ies) available for mofezolac and aspirin
| Article | Year |
|---|---|
Cyclooxygenase-1-selective inhibitors are attractive candidates for analgesics that do not cause gastric damage. design and in vitro/in vivo evaluation of a benzamide-type cyclooxygenase-1 selective inhibitor.
Topics: Aminopyridines; Animals; Benzamides; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred ICR; Molecular Structure; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Stomach | 2008 |
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Binding Sites; Bortezomib; Cell Cycle; Cell Line, Tumor; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Humans; Isoxazoles; Multiple Myeloma; Platelet Aggregation Inhibitors; Protein Binding; Structure-Activity Relationship | 2019 |
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid.
Topics: Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blood Coagulation; Chlorocebus aethiops; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Erythrocytes; Humans; Isoxazoles; Models, Molecular; Protein Binding; Protein Multimerization; Structure-Activity Relationship; Thrombosis; Vero Cells | 2021 |
Development of Fluorescence Imaging Probes for Labeling COX-1 in Live Ovarian Cancer Cells.
Topics: | 2021 |
COX-2/VEGF-dependent facilitation of tumor-associated angiogenesis and tumor growth in vivo.
Topics: Animals; Antibodies, Blocking; Aspirin; Benzenesulfonates; Carcinoma, Lewis Lung; Cyclooxygenase Inhibitors; Disease Models, Animal; Endothelial Growth Factors; Intercellular Signaling Peptides and Proteins; Isoxazoles; Lymphokines; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neovascularization, Pathologic; Nitrobenzenes; Oxazoles; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sarcoma 180; Sulfonamides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |