modipafant has been researched along with leukotriene b4 in 6 studies
| Studies (modipafant) | Trials (modipafant) | Recent Studies (post-2010) (modipafant) | Studies (leukotriene b4) | Trials (leukotriene b4) | Recent Studies (post-2010) (leukotriene b4) |
|---|---|---|---|---|---|
| 29 | 3 | 3 | 5,886 | 232 | 717 |
| Protein | Taxonomy | modipafant (IC50) | leukotriene b4 (IC50) |
|---|---|---|---|
| Leukotriene B4 receptor 1 | Homo sapiens (human) | 0.0019 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bolanowski, MA; Nourshargh, S; Sanz, MJ; Weg, VB | 1 |
| Nourshargh, S; Sanz, MJ; Walsh, DT; Weg, VB; Williams, TJ | 1 |
| Benjamim, CF; Cunha, Fde Q; Ferreira, SH; Rios-Santos, F; Zavery, D | 1 |
| Bélanger, C; Borgeat, P; Elimam, H; Lefebvre, J; Marleau, S | 1 |
| Borgeat, P; Flamand, N; Lefebvre, JS; Lévesque, T; Marleau, S; Milot, V; Picard, S | 1 |
| Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Pinto, LG; Verri, WA; Vieira, SM; Zaperlon, AC; Zarpelon, AC | 1 |
6 other study(ies) available for modipafant and leukotriene b4
| Article | Year |
|---|---|
IL-1 is a potent inducer of eosinophil accumulation in rat skin. Inhibition of response by a platelet-activating factor antagonist and an anti-human IL-8 antibody.
Topics: Animals; Antibodies, Monoclonal; Calcium; Chemotaxis, Leukocyte; Dactinomycin; Dihydropyridines; Edema; Eosinophils; Imidazoles; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-8; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Skin | 1995 |
Differential effects of the PAF receptor antagonist UK-74,505 on neutrophil and eosinophil accumulation in guinea-pig skin.
Topics: Animals; Blood Proteins; Calcium; Dihydropyridines; Edema; Eosinophils; Female; Guinea Pigs; Imidazoles; Leukotriene B4; Neutrophils; Passive Cutaneous Anaphylaxis; Peritoneal Cavity; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Skin; Zymosan | 1994 |
A critical role of leukotriene B4 in neutrophil migration to infectious focus in cecal ligaton and puncture sepsis.
Topics: Animals; Cecum; Cell Movement; Dihydropyridines; Eicosanoids; Imidazoles; Indoles; Inflammation; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred C57BL; Neutrophils; Peritoneum; Platelet Activating Factor; Prostaglandins; Time Factors; Wounds, Penetrating | 2003 |
Involvement of endogenous leukotriene B4 and platelet-activating factor in polymorphonuclear leucocyte recruitment to dermal inflammatory sites in rats.
Topics: Animals; Benzopyrans; Carboxylic Acids; Dermatitis; Dihydropyridines; Imidazoles; Leukotriene B4; Male; Neutrophil Infiltration; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pneumonia; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Leukotriene B4; Skin; Thiazoles | 2008 |
Toll-like receptor ligands induce polymorphonuclear leukocyte migration: key roles for leukotriene B4 and platelet-activating factor.
Topics: Animals; Azepines; Cell Movement; Dihydropyridines; Female; Flagellin; Humans; Imidazoles; Leukotriene B4; Ligands; Mice; Mice, Inbred C57BL; Neutrophils; Platelet Activating Factor; Poly I-C; Propionates; Quinolines; Thienopyridines; Toll-Like Receptors; Triazoles | 2010 |
The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Immune System Diseases; Inflammation; Joint Diseases; Leukocyte Disorders; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, G-Protein-Coupled; Time Factors; Zymosan | 2013 |