Page last updated: 2024-09-03

modipafant and bepafant

modipafant has been researched along with bepafant in 5 studies

Compound Research Comparison

Studies
(modipafant)
Trials
(modipafant)
Recent Studies (post-2010)
(modipafant)
Studies
(bepafant)
Trials
(bepafant)
Recent Studies (post-2010) (bepafant)
60017405
293317405

Protein Interaction Comparison

ProteinTaxonomymodipafant (IC50)bepafant (IC50)
Platelet-activating factor receptorCavia porcellus (domestic guinea pig)0.073

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cooper, K; Fray, MJ; Parry, MJ; Richardson, K; Steele, J1
Bull, DJ; Cooper, K; Fray, MJ; Parry, MJ; Stefaniak, MH1
Bures, MG; Carrera, GM; Davidsen, SK; Guinn, DE; Heyman, HR; May, PD; Phillips, JG; Pireh, D; Sheppard, GS; Steinman, DH1
Das, A; Larkin, SW; Nourshargh, S; Williams, TJ1
Andrade, SP; Cara, DC; Cassali, GD; Coutinho, SF; Poole, SP; Silveira, MR; Souza, DG; Teixeira, MM1

Other Studies

5 other study(ies) available for modipafant and bepafant

ArticleYear
Novel antagonists of platelet-activating factor. 1. Synthesis and structure-activity relationships of benzodiazepine and benzazepine derivatives of 2-methyl-1-phenylimidazo[4,5-c]pyridine.
    Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18

    Topics: Animals; Azepines; Benzodiazepines; Imidazoles; Mice; Platelet Activating Factor; Pyridines; Rabbits; Structure-Activity Relationship; Thiazoles; Triazoles

1995
Novel antagonists of platelet-activating factor. 2. Synthesis and structure-activity relationships of potent and long-acting heterofused [1,5]benzodiazepine and [1,4]diazepine derivatives of 2-methyl-1-phenylimidazo[4,5-c]pyridine.
    Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18

    Topics: Animals; Azepines; Benzene; Benzodiazepines; Dihydropyridines; Dogs; Imidazoles; In Vitro Techniques; Mice; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrazoles; Pyridines; Rabbits; Structure-Activity Relationship; X-Ray Diffraction

1995
3-(2-(3-Pyridinyl)thiazolidin-4-oyl)indoles, a novel series of platelet activating factor antagonists.
    Journal of medicinal chemistry, 1994, Jun-24, Volume: 37, Issue:13

    Topics: Administration, Oral; Animals; Capillary Permeability; Edema; In Vitro Techniques; Indoles; Magnetic Resonance Spectroscopy; Male; Mice; Platelet Activating Factor; Rabbits; Rats; Rats, Sprague-Dawley; Serotonin; Skin; Stereoisomerism; Structure-Activity Relationship; Thiazoles

1994
Interleukin-1-induced leukocyte extravasation across rat mesenteric microvessels is mediated by platelet-activating factor.
    Blood, 1995, May-01, Volume: 85, Issue:9

    Topics: Animals; Azepines; Cell Adhesion; Chemotaxis, Leukocyte; Dihydropyridines; Edema; Imidazoles; Inflammation; Interleukin-1; Leukocytes; Male; Mesentery; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins; Skin; Triazoles

1995
Effects of the PAF receptor antagonist UK74505 on local and remote reperfusion injuries following ischaemia of the superior mesenteric artery in the rat.
    British journal of pharmacology, 2000, Volume: 131, Issue:8

    Topics: Animals; Azepines; Capillary Permeability; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Imidazoles; Intestine, Small; Male; Mesenteric Artery, Superior; Neutrophils; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Polysaccharides; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reperfusion Injury; Triazoles; Tumor Necrosis Factor-alpha

2000