modafinil has been researched along with piperidines in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 13 (50.00) | 24.3611 |
| 2020's | 6 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Hajdukovic, R; Mitler, MM | 1 |
| Holcomb, HH; Schweitzer, JB | 1 |
| He, R; Johnson, KM; Kozikowski, AP; Ye, Y; Zhou, J | 1 |
| Camblor, E; Fernández, R; Janeiro, M; Núñez, D | 1 |
| Fujiki, N; Honda, Y; Kodama, T; Nishino, S; Song, YH; Soya, A | 1 |
| Anaclet, C; Arnulf, I; Bastuji, H; Dauvilliers, Y; Kocher, L; Lecomte, JM; Lehert, P; Ligneau, X; Lin, JS; Parmentier, R; Perrin, D; Robert, P; Roux, M; Schwartz, JC; Yanagisawa, M | 1 |
| Boesjes, H; Galvin, E; Hol, J; Klein, J; Ubben, JF; Verbrugge, SJ | 1 |
| Stix, G | 1 |
| Harada, K; Moguchi, T; Morimoto, Y; Nogami, Y; Shiramoto, H | 1 |
| Beardsley, PM; Belliard, S; Lecomte, JM; Ligneau, X; Perrin, D; Schwartz, JC; Uguen, M | 1 |
| Strambi, LF | 1 |
| Arnulf, I; Bassetti, C; Dauvilliers, Y; Ding, CL; Lammers, GJ; Lecomte, JM; Lehert, P; Mayer, G; Rodenbeck, A; Schwartz, JC | 1 |
| Borghgraef, C; Delvaux, N; Etienne, AM; Libert, Y; Razavi, D; Reynaert, C | 1 |
| Castellino, SM; Lange, BJ; Ullrich, NJ; Whelen, MJ | 1 |
| Brown, PD; Day, J; Gehring, K; Grant, R; Grosshans, D; Li, J; Taphoorn, M; Zienius, K | 1 |
| Arnulf, I; Bassetti, CL; Dauvilliers, Y; Ding, CL; Lammers, GJ; Lehert, P; Mayer, G; van der Heide, A; van Dijk, JG; van Schie, MK | 1 |
| Agrawal, N; Dougall, D; Poole, N | 1 |
| Bassetti, CL; Kallweit, U | 1 |
| Falissard, B; Lehert, P | 1 |
| Arnulf, I; Dodet, P; Leu-Semenescu, S | 1 |
| Javaheri, S | 1 |
| de Biase, S; Gigli, GL; Pellitteri, G; Valente, M | 1 |
| Bonifazi, A; Cao, J; Coggiano, MA; Giancola, JB; Haraczy, AJ; Ku, T; Lam, J; Newman, AH; Rais, R; Tanda, G | 1 |
| Cavalli, F; Franceschini, C; Pizza, F; Plazzi, G | 1 |
| Belliard, S; Berrebi-Bertrand, I; Finance, O; Giret, M; Krief, S; Lecomte, JM; Ligneau, X; Nagmar, I; Perrin, D; Robert, P; Schwartz, JC; Uguen, M | 1 |
| Apel, D; Ellwardt, E; Fleischer, V; Groppa, S; Kallweit, U; Lang, C; Winter, Y | 1 |
11 review(s) available for modafinil and piperidines
| Article | Year |
|---|---|
Drugs under investigation for attention-deficit hyperactivity disorder.
Topics: Animals; Antidepressive Agents; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Benzhydryl Compounds; Central Nervous System Stimulants; Clinical Trials as Topic; Cyclobutanes; Donepezil; Histamine Agonists; Humans; Indans; Modafinil; Nootropic Agents; Piperidines; Propylamines | 2002 |
[Treatment of cognitive impairments in oncology: a review of longitudinal controlled studies].
Topics: Adult; Benzhydryl Compounds; Case-Control Studies; Central Nervous System Stimulants; Cognition; Cognition Disorders; Darbepoetin alfa; Donepezil; Erythropoietin; Estradiol; Executive Function; Female; Humans; Indans; Longitudinal Studies; Male; Meditation; Methylphenidate; Modafinil; Neoplasms; Piperidines | 2014 |
Developing interventions for cancer-related cognitive dysfunction in childhood cancer survivors.
Topics: Adolescent; Adult; Age Factors; Antimetabolites, Antineoplastic; Attention; Benzhydryl Compounds; Brain Neoplasms; Central Nervous System Stimulants; Child; Child, Preschool; Cognitive Dysfunction; Comorbidity; Cranial Irradiation; Donepezil; Early Intervention, Educational; Education, Special; Head and Neck Neoplasms; Human Growth Hormone; Humans; Indans; Infant; Injections, Spinal; Memory, Short-Term; Methotrexate; Methylphenidate; Modafinil; Neoplasms; Neurosurgical Procedures; Nootropic Agents; Patient Education as Topic; Piperidines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychomotor Performance; Quality of Life; Radiotherapy Dosage; Risk Factors; Severity of Illness Index; Sex Factors; Survivors; Thinking; Wakefulness-Promoting Agents; Young Adult | 2014 |
Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation.
Topics: Adult; Benzhydryl Compounds; Cognition Disorders; Cranial Irradiation; Donepezil; Humans; Indans; Memantine; Methylphenidate; Modafinil; Nootropic Agents; Piperidines; Randomized Controlled Trials as Topic | 2014 |
Pharmacotherapy for chronic cognitive impairment in traumatic brain injury.
Topics: Adolescent; Adult; Aged; Atomoxetine Hydrochloride; Benzhydryl Compounds; Brain Injuries; Chronic Disease; Cognition; Cognition Disorders; Humans; Middle Aged; Modafinil; Nootropic Agents; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine | 2015 |
Pharmacological management of narcolepsy with and without cataplexy.
Topics: Adult; Benzhydryl Compounds; Cataplexy; Drug Therapy, Combination; Humans; Modafinil; Narcolepsy; Neuropeptides; Off-Label Use; Orexins; Piperidines; Quality of Life; Sleep; Sodium Oxybate; Venlafaxine Hydrochloride; Wakefulness-Promoting Agents | 2017 |
Multiple treatment comparison in narcolepsy: a network meta-analysis.
Topics: Adult; Cataplexy; Humans; Modafinil; Narcolepsy; Network Meta-Analysis; Odds Ratio; Piperidines; Risk Assessment; Sleepiness; Sodium Oxybate | 2018 |
Precision Medicine for Idiopathic Hypersomnia.
Topics: Central Nervous System Stimulants; Clarithromycin; Flumazenil; GABA Modulators; Humans; Idiopathic Hypersomnia; Mazindol; Modafinil; Orexins; Piperidines; Polysomnography; Precision Medicine; Sleep; Sodium Oxybate; Wakefulness; Wakefulness-Promoting Agents | 2019 |
Update on Persistent Excessive Daytime Sleepiness in OSA.
Topics: Carbamates; Disorders of Excessive Somnolence; Humans; Modafinil; Phenylalanine; Piperidines; Sleep Apnea, Obstructive; Wakefulness-Promoting Agents | 2020 |
Evaluating pitolisant as a narcolepsy treatment option.
Topics: Animals; Cataplexy; Humans; Modafinil; Narcolepsy; Piperidines; Sleep; Sodium Oxybate; Treatment Outcome | 2021 |
A practical guide to the pharmacological and behavioral therapy of Narcolepsy.
Topics: Behavior Therapy; Carbamates; Counseling; Humans; Modafinil; Narcolepsy; Phenylalanine; Piperidines; Wakefulness-Promoting Agents | 2021 |
5 trial(s) available for modafinil and piperidines
| Article | Year |
|---|---|
Relative efficacy of drugs for the treatment of sleepiness in narcolepsy.
Topics: Adult; Arousal; Benzhydryl Compounds; Central Nervous System Stimulants; Codeine; Dextroamphetamine; Female; Humans; Male; Methylphenidate; Modafinil; Narcolepsy; Pemoline; Piperidines; Protriptyline; Reaction Time; Ritanserin; Sleep Stages; Sodium Oxybate; Viloxazine; Wakefulness | 1991 |
An inverse agonist of the histamine H(3) receptor improves wakefulness in narcolepsy: studies in orexin-/- mice and patients.
Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Disease Models, Animal; Female; Histamine Agonists; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Modafinil; Narcolepsy; Neuropeptides; Orexins; Piperidines; Polysomnography; Prospective Studies; Reaction Time; Severity of Illness Index; Single-Blind Method; Sleep Stages; Wakefulness | 2008 |
Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Appetite; Benzhydryl Compounds; Central Nervous System Stimulants; Deep Sedation; Dizziness; Fatigue; Fentanyl; Humans; Lithotripsy; Midazolam; Middle Aged; Modafinil; Nausea; Neuropsychological Tests; Pain; Piperidines; Placebos; Propofol; Psychomotor Agitation; Psychomotor Performance; Relaxation; Remifentanil; Sleep Stages; Young Adult | 2010 |
Pitolisant versus placebo or modafinil in patients with narcolepsy: a double-blind, randomised trial.
Topics: Adult; Benzhydryl Compounds; Double-Blind Method; Female; Histamine Agonists; Humans; Male; Middle Aged; Modafinil; Narcolepsy; Piperidines; Placebos; Severity of Illness Index; Treatment Outcome; Wakefulness-Promoting Agents; Young Adult | 2013 |
Comparing Treatment Effect Measurements in Narcolepsy: The Sustained Attention to Response Task, Epworth Sleepiness Scale and Maintenance of Wakefulness Test.
Topics: Adult; Attention; Benzhydryl Compounds; Cataplexy; Double-Blind Method; Female; Humans; Male; Modafinil; Narcolepsy; Piperidines; Reproducibility of Results; Sleep Stages; Time Factors; Treatment Outcome; Wakefulness | 2015 |
10 other study(ies) available for modafinil and piperidines
| Article | Year |
|---|---|
Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: efficient drug discovery by rational lead hybridization.
Topics: Animals; Benzhydryl Compounds; Biological Availability; Cocaine; Dopamine Plasma Membrane Transport Proteins; Drug Design; In Vitro Techniques; Ligands; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Modafinil; Motor Activity; Nerve Endings; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Rats; Serotonin Plasma Membrane Transport Proteins; Symporters; Synaptosomes | 2004 |
[Narcolepsy and anesthesia].
Topics: Analgesia, Epidural; Anesthesia, Intravenous; Antiemetics; Benzhydryl Compounds; Chemical and Drug Induced Liver Injury; Clomipramine; Contraindications; Humans; Hypnotics and Sedatives; Intracellular Signaling Peptides and Proteins; Intraoperative Complications; Kidney Pelvis; Modafinil; Narcolepsy; Neuropeptides; Ondansetron; Orexins; Pain, Postoperative; Piperidines; Preanesthetic Medication; Propofol; Remifentanil; Ureteral Obstruction | 2007 |
CSF histamine levels in rats reflect the central histamine neurotransmission.
Topics: Amphetamine; Animals; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Circadian Rhythm; Disorders of Excessive Somnolence; Food Deprivation; Histamine; Male; Modafinil; Motor Activity; Piperidines; Rats; Rats, Sprague-Dawley; Sleep; Sleep Deprivation; Synaptic Transmission; Wakefulness | 2008 |
Turbocharging the brain.
Topics: Alzheimer Disease; Benzhydryl Compounds; Brain; Central Nervous System Agents; Central Nervous System Stimulants; Cognition; Donepezil; Drug Industry; Humans; Indans; Legislation, Drug; Memory; Methylphenidate; Modafinil; Nootropic Agents; Piperidines; United States; United States Food and Drug Administration | 2009 |
Anesthetic management of a patient with narcolepsy.
Topics: Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Benzhydryl Compounds; Central Nervous System Stimulants; Consciousness Monitors; Endoscopy; Flurbiprofen; Humans; Hypnotics and Sedatives; Male; Methyl Ethers; Modafinil; Narcolepsy; Pain, Postoperative; Piperidines; Remifentanil; Rhinitis, Allergic, Perennial; Sevoflurane; Sinusitis; Young Adult | 2011 |
Preclinical evaluation of the abuse potential of Pitolisant, a histamine H₃ receptor inverse agonist/antagonist compared with Modafinil.
Topics: Animals; Behavior, Addictive; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Drug Antagonism; Drug Evaluation, Preclinical; Drug Inverse Agonism; Drugs, Investigational; Histamine Agonists; Histamine Antagonists; Macaca mulatta; Male; Mice; Modafinil; Motor Activity; Nucleus Accumbens; Piperidines; Rats; Receptors, Histamine H3; Wakefulness-Promoting Agents | 2013 |
A need for new treatments in narcolepsy.
Topics: Benzhydryl Compounds; Female; Histamine Agonists; Humans; Male; Modafinil; Narcolepsy; Piperidines; Wakefulness-Promoting Agents | 2013 |
Structure-activity relationships for a series of (Bis(4-fluorophenyl)methyl)sulfinylethyl-aminopiperidines and -piperidine amines at the dopamine transporter: Bioisosteric replacement of the piperazine improves metabolic stability.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Dopamine Plasma Membrane Transport Proteins; Drug Stability; Guinea Pigs; Locomotion; Male; Mice; Microsomes, Liver; Modafinil; Molecular Structure; Piperidines; Rats, Sprague-Dawley; Receptors, sigma; Serotonin Plasma Membrane Transport Proteins; Sigma-1 Receptor; Structure-Activity Relationship | 2020 |
Pitolisant, a wake-promoting agent devoid of psychostimulant properties: Preclinical comparison with amphetamine, modafinil, and solriamfetol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Carbamates; Corpus Striatum; Disorders of Excessive Somnolence; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Evaluation, Preclinical; Drug Inverse Agonism; Feeding Behavior; Histamine Antagonists; Locomotion; Mice; Modafinil; Narcolepsy; Neostriatum; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; Phenylalanine; Piperidines; Receptors, Histamine H3; Sleep Apnea, Obstructive; Wakefulness-Promoting Agents | 2021 |
Pitolisant-supported bridging during drug holidays to deal with tolerance to modafinil in patients with narcolepsy.
Topics: Benzhydryl Compounds; Disorders of Excessive Somnolence; Humans; Modafinil; Narcolepsy; Piperidines; Quality of Life | 2023 |