modafinil and gamma-aminobutyric acid

modafinil has been researched along with gamma-aminobutyric acid in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (60.00)18.2507
2000's6 (30.00)29.6817
2010's2 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bianchi, C; Ferraro, L; Fuxe, K; Janson, AM; Tanganelli, S1
Beani, L; Ferraro, L; Fuxe, K; Méndez-Franco, J; Pérez de la Mora, M; Rambert, FA; Tanganelli, S1
Bianchi, C; Ferraro, L; Fuxe, K; Tanganelli, S1
Bettendorff, L; Margineanu, I; Sallanon-Moulin, M; Schoffeniels, E; Touret, M; Wins, P1
Antonelli, T; Ferraro, L; Fuxe, K; O'Connor, WT; Rambert, F; Tanganelli, S3
Antonelli, T; Ferraro, L; Fuxe, K; O'Connor, WT; Rambert, FA; Tanganelli, S2
Antonelli, T; Ferraro, L; Fuxe, K; Hillion, J; Rambert, FA; Tomasini, MC1
Aguilar-García, A; Fuxe, K; Méndez-Franco, J; Pérez de la Mora, M; Rambert, F; Ramírez-Ramírez, R; Ramon-Frías, T1
Antonelli, T; Ferraro, L; Fuxe, K; Mendez-Franco, J; O'Connor, WT; Perez de la Mora, M; Rambert, FA; Tanganelli, S1
Dong, Z; Fu, JM; He, BC; Xiao, YL; Yang, JQ; Zeng, FX; Zhu, LX1
Kosten, TR; Sofuoglu, M1
Leznik, E; Llinás, RR; Urbano, FJ1
Huang, Q; Tang, H; Wang, L; Wang, Y; Zhang, L1
Akins, BE; Lacy, JM; Logan, BK; Miranda, E1
Citrome, L; Javitt, D; Kantrowitz, J1
Beck, P; Garcia-Rill, E; Hyde, J; Kezunovic, N; Simon, C; Urbano, FJ1
Born, J; Hallschmid, M; Klement, J; Lehnert, H; Mergelkuhl, B1

Reviews

3 review(s) available for modafinil and gamma-aminobutyric acid

ArticleYear
Emerging pharmacological strategies in the fight against cocaine addiction.
    Expert opinion on emerging drugs, 2006, Volume: 11, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disulfiram; Dopamine; Dopamine Agents; Dopamine beta-Hydroxylase; Drug Evaluation, Preclinical; Enzyme Inhibitors; GABA Agonists; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Humans; Modafinil; Nipecotic Acids; Propranolol; Randomized Controlled Trials as Topic; Tiagabine; Vaccines

2006
GABA(B) receptors, schizophrenia and sleep dysfunction: a review of the relationship and its potential clinical and therapeutic implications.
    CNS drugs, 2009, Volume: 23, Issue:8

    Topics: Animals; Antipsychotic Agents; Benzhydryl Compounds; Central Nervous System Depressants; Central Nervous System Stimulants; GABA Agents; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Learning; Melatonin; Modafinil; Neuropsychological Tests; Polysomnography; Receptors, GABA-B; Schizophrenia; Sleep Wake Disorders

2009
Coherence and frequency in the reticular activating system (RAS).
    Sleep medicine reviews, 2013, Volume: 17, Issue:3

    Topics: Animals; Awareness; Benzhydryl Compounds; Beta Rhythm; Calcium Channels; Central Nervous System Stimulants; Cerebral Cortex; Electroencephalography; gamma-Aminobutyric Acid; Humans; Intralaminar Thalamic Nuclei; Locus Coeruleus; Modafinil; Neural Pathways; Neurons; Pedunculopontine Tegmental Nucleus; Pons; Reticular Formation; Signal Processing, Computer-Assisted; Sleep; Sodium Channels; Synaptic Transmission; Wakefulness

2013

Other Studies

17 other study(ies) available for modafinil and gamma-aminobutyric acid

ArticleYear
Inhibitory effects of the psychoactive drug modafinil on gamma-aminobutyric acid outflow from the cerebral cortex of the awake freely moving guinea-pig. Possible involvement of 5-hydroxytryptamine mechanisms.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:4

    Topics: Acetylcholine; Animals; Benzhydryl Compounds; Cerebral Cortex; Corpus Striatum; Female; gamma-Aminobutyric Acid; Guinea Pigs; Male; Mice; Mice, Inbred C57BL; Modafinil; Rats; Rats, Inbred Strains; Serotonin

1992
Modafinil and cortical gamma-aminobutyric acid outflow. Modulation by 5-hydroxytryptamine neurotoxins.
    European journal of pharmacology, 1995, Jan-24, Volume: 273, Issue:1-2

    Topics: 5,7-Dihydroxytryptamine; Animals; Benzhydryl Compounds; Catecholamines; Central Nervous System Stimulants; Cerebral Cortex; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Modafinil; Neurotoxins; Rats; Rats, Wistar; Serotonin; Serotonin Agents

1995
6-hydroxy-dopamine treatment counteracts the reduction of cortical GABA release produced by the vigilance promoting drug modafinil in the awake freely moving guinea-pig.
    Neuroscience letters, 1994, Apr-25, Volume: 171, Issue:1-2

    Topics: Animals; Arousal; Benzhydryl Compounds; Biogenic Monoamines; Catecholamines; Central Nervous System Stimulants; Cerebral Cortex; gamma-Aminobutyric Acid; Guinea Pigs; Injections, Intraventricular; Modafinil; Oxidopamine

1994
Paradoxical sleep deprivation increases the content of glutamate and glutamine in rat cerebral cortex.
    Sleep, 1996, Volume: 19, Issue:1

    Topics: Animals; Arousal; Benzhydryl Compounds; Central Nervous System Stimulants; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamine; Male; Modafinil; Rats; Sleep Deprivation; Wakefulness

1996
The vigilance promoting drug modafinil increases dopamine release in the rat nucleus accumbens via the involvement of a local GABAergic mechanism.
    European journal of pharmacology, 1996, Jun-13, Volume: 306, Issue:1-3

    Topics: Analysis of Variance; Animals; Baclofen; Benzhydryl Compounds; Central Nervous System Stimulants; Dopamine; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Modafinil; Muscimol; Nipecotic Acids; Nucleus Accumbens; Rats; Rats, Sprague-Dawley

1996
The vigilance promoting drug modafinil decreases GABA release in the medial preoptic area and in the posterior hypothalamus of the awake rat: possible involvement of the serotonergic 5-HT3 receptor.
    Neuroscience letters, 1996, Dec-06, Volume: 220, Issue:1

    Topics: Animals; Arousal; Benzhydryl Compounds; Central Nervous System Stimulants; gamma-Aminobutyric Acid; Hypothalamus, Posterior; Male; Methysergide; Modafinil; Preoptic Area; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tropanes

1996
The antinarcoleptic drug modafinil increases glutamate release in thalamic areas and hippocampus.
    Neuroreport, 1997, Sep-08, Volume: 8, Issue:13

    Topics: Animals; Benzhydryl Compounds; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Modafinil; Rats; Rats, Sprague-Dawley; Sleep; Thalamus

1997
Modafinil: an antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers.
    Biological psychiatry, 1997, Dec-15, Volume: 42, Issue:12

    Topics: Animals; Benzhydryl Compounds; Biogenic Amines; Central Nervous System Stimulants; Dextroamphetamine; Dopamine; Dopamine Uptake Inhibitors; gamma-Aminobutyric Acid; Male; Microdialysis; Modafinil; Narcolepsy; Nucleus Accumbens; Piperazines; Rats; Rats, Sprague-Dawley

1997
The effects of modafinil on striatal, pallidal and nigral GABA and glutamate release in the conscious rat: evidence for a preferential inhibition of striato-pallidal GABA transmission.
    Neuroscience letters, 1998, Sep-04, Volume: 253, Issue:2

    Topics: Animals; Benzhydryl Compounds; Corpus Striatum; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; Injections, Intraperitoneal; Male; Microdialysis; Modafinil; Rats; Rats, Sprague-Dawley; Substantia Nigra; Synaptic Transmission; Time Factors; Wakefulness

1998
Modafinil prevents glutamate cytotoxicity in cultured cortical neurons.
    Neuroreport, 1998, Dec-21, Volume: 9, Issue:18

    Topics: Animals; Benzhydryl Compounds; Cells, Cultured; Central Nervous System Stimulants; Cerebral Cortex; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Modafinil; Neurons; Rats; Rats, Sprague-Dawley; Reference Values

1998
Effects of the vigilance promoting drug modafinil on the synthesis of GABA and glutamate in slices of rat hypothalamus.
    Neuroscience letters, 1999, Jan-15, Volume: 259, Issue:3

    Topics: Animals; Arousal; Benzhydryl Compounds; Central Nervous System Stimulants; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Male; Modafinil; Rats; Rats, Wistar

1999
The vigilance promoting drug modafinil increases extracellular glutamate levels in the medial preoptic area and the posterior hypothalamus of the conscious rat: prevention by local GABAA receptor blockade.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:4

    Topics: Amino Acids; Animals; Arousal; Benzhydryl Compounds; Central Nervous System Stimulants; Extracellular Space; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus, Posterior; Male; Microdialysis; Modafinil; Preoptic Area; Rats; Rats, Sprague-Dawley; Stimulation, Chemical

1999
Neuroprotective mechanism of modafinil on Parkinson disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:3

    Topics: Animals; Benzhydryl Compounds; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Modafinil; MPTP Poisoning; Neuroprotective Agents; Norepinephrine; Serotonin; Substantia Nigra

2004
Modafinil enhances thalamocortical activity by increasing neuronal electrotonic coupling.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Jul-24, Volume: 104, Issue:30

    Topics: Animals; Benzhydryl Compounds; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cerebral Cortex; Electrons; Electrophysiology; gamma-Aminobutyric Acid; Mice; Modafinil; Neurons; Rats; Thalamus

2007
Modafinil modulates GABA-activated currents in rat hippocampal pyramidal neurons.
    Brain research, 2008, May-07, Volume: 1208

    Topics: Animals; Animals, Newborn; Benzhydryl Compounds; Cells, Cultured; Drug Interactions; gamma-Aminobutyric Acid; Glyburide; Hippocampus; Hypoglycemic Agents; Membrane Potentials; Modafinil; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley

2008
A multi-drug intoxication fatality involving Xyrem (GHB).
    Journal of forensic sciences, 2009, Volume: 54, Issue:2

    Topics: Amines; Benzhydryl Compounds; Carisoprodol; Central Nervous System Depressants; Cetirizine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Female; Forensic Toxicology; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Contents; Humans; Middle Aged; Modafinil; Narcolepsy; Sleep Apnea Syndromes; Snoring; Sodium Oxybate; Tramadol; Vitreous Body

2009
Role of γ-aminobutyric acid signalling in the attenuation of counter-regulatory hormonal responses after antecedent hypoglycaemia in healthy men.
    Diabetes, obesity & metabolism, 2014, Volume: 16, Issue:12

    Topics: Adrenocorticotropic Hormone; Adult; Analysis of Variance; Benzhydryl Compounds; Blood Glucose; Cytochrome P-450 CYP3A Inducers; Double-Blind Method; gamma-Aminobutyric Acid; Growth Hormone; Healthy Volunteers; Humans; Hydrocortisone; Hypoglycemia; Male; Modafinil; Norepinephrine; Signal Transduction

2014