modafinil and clozapine

modafinil has been researched along with clozapine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's5 (45.45)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Millan, MJ; Sebban, C; Spedding, M; Tesolin-Decros, B1
Narendran, R; Nickolova, MK; Pristach, CA; Valenti, AM; Young, CM1
Dequardo, JR2
Cather, C; Evins, AE; Fan, X; Freudenreich, O; Goff, DC; Henderson, DC; Macklin, EA; Walsh, JP1
Borba, CP; Cather, C; Copeland, PM; Fan, X; Freudenreich, O; Goff, DC; Henderson, DC; Macklin, E; Wang, X1

Reviews

1 review(s) available for modafinil and clozapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for modafinil and clozapine

ArticleYear
Modafinil for clozapine-treated schizophrenia patients: a double-blind, placebo-controlled pilot trial.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:12

    Topics: Adolescent; Adult; Antipsychotic Agents; Benzhydryl Compounds; Central Nervous System Stimulants; Clozapine; Cognition Disorders; Double-Blind Method; Drug Therapy, Combination; Fatigue; Female; Humans; Male; Middle Aged; Modafinil; Neuropsychological Tests; Pilot Projects; Placebos; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Wakefulness

2009
Effects of modafinil on weight, glucose and lipid metabolism in clozapine-treated patients with schizophrenia.
    Schizophrenia research, 2011, Volume: 130, Issue:1-3

    Topics: Adult; Analysis of Variance; Benzhydryl Compounds; Blood Glucose; Blood Pressure; Body Weight; Clozapine; Double-Blind Method; Female; Follow-Up Studies; Humans; Lipid Metabolism; Male; Metabolic Diseases; Middle Aged; Modafinil; Neuroprotective Agents; Retrospective Studies; Schizophrenia; Time Factors

2011

Other Studies

8 other study(ies) available for modafinil and clozapine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Contrasting EEG profiles elicited by antipsychotic agents in the prefrontal cortex of the conscious rat: antagonism of the effects of clozapine by modafinil.
    British journal of pharmacology, 1999, Volume: 128, Issue:5

    Topics: Animals; Antipsychotic Agents; Apomorphine; Benzhydryl Compounds; Central Nervous System Stimulants; Clozapine; Dopamine Agonists; Electroencephalography; Injections, Subcutaneous; Male; Modafinil; Motor Cortex; Prefrontal Cortex; Rats; Rats, Wistar; Somatosensory Cortex

1999
Is psychosis exacerbated by modafinil?
    Archives of general psychiatry, 2002, Volume: 59, Issue:3

    Topics: Benzhydryl Compounds; Clozapine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Middle Aged; Modafinil; Narcolepsy; Schizophrenia; Schizophrenic Psychology

2002
Modafinil-associated clozapine toxicity.
    The American journal of psychiatry, 2002, Volume: 159, Issue:7

    Topics: Adult; Antipsychotic Agents; Benzhydryl Compounds; Central Nervous System Stimulants; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Humans; Male; Modafinil; Schizophrenia; Sleep

2002
Modafinil and antipsychotic-induced sedation.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:2

    Topics: Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Benzhydryl Compounds; Clozapine; Cytochrome P-450 CYP2C19; Disorders of Excessive Somnolence; Drug Interactions; Humans; Mixed Function Oxygenases; Modafinil; Schizophrenia

2004