modafinil and caffeine

modafinil has been researched along with caffeine in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.82)18.2507
2000's23 (41.82)29.6817
2010's22 (40.00)24.3611
2020's9 (16.36)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Akerstedt, T; Ficca, G1
Edgar, DM; Mignot, E; Nishino, S; Sora, I; Uhl, GH; Wisor, JP1
Balkin, TJ; Belenky, G; Kautz, MA; Reichardt, RM; Thorne, DR; Wesensten, NJ1
Hall, SS1
Balkin, TJ; Belenky, G; Kautz, MA; Thorne, DR; Wesensten, NJ1
Hunsley, MS; Palmiter, RD1
Bonneau, D; Drogou, C; Etienne, X; Florence, G; Gomez-Merino, D; Huart, B; Pradeau, P; Riondet, L; Serra, A; van Beers, P1
Kaplan, J; Malik, SW1
Balkin, TJ; Killgore, WD; Wesensten, NJ1
Balkin, TJ; Bonnet, MH; Dinges, DF; Roehrs, T; Rogers, NL; Wesensten, NJ1
Batéjat, D; Beaumont, M; Coste, O; Lagarde, D; Piérard, C; Van Beers, P1
Balkin, TJ; Killgore, DB; Killgore, WD; McBride, SA1
Dagan, Y; Doljansky, JT1
Roth, T; Schwartz, JR1
Darwish, M; Hellriegel, ET; Kirby, M; Robertson, P1
Grugle, NL; Huck, NO; Kendall, AP; Killgore, WD; McBride, SA1
Balkin, TJ; Grugle, NL; Killgore, WD; Lipizzi, EL; Reichardt, RM; Rupp, TL1
Arnett, MV; Caldwell, JA; Russo, MB; Thomas, ML1
Balkin, TJ; Grugle, NL; Killgore, DB; Killgore, WD; Leavitt, BP; McNair, S; Watlington, GI1
Balkin, TJ; Grugle, NL; Killgore, DB; Killgore, WD; Muckle, AE1
Majeroni, BA; Malik, K; Pretorius, R; Rosenthal, TC1
Balkin, TJ; Grugle, NL; Kahn-Greene, ET; Killgore, DB; Killgore, WD1
Balkin, TJ; Grugle, NL; Killgore, DB; Killgore, WD1
Dimitriu, A; Guilleminault, C; Zaharna, M1
Ali, M; Auger, RR; Morgenthaler, TI; Slocumb, NL1
Fujiki, N; Ishimaru, Y; Kotorii, N; Nishino, S; Okuro, M; Sokoloff, P1
Gore, RK; Hermes, ED; Webb, TS1
Dasheiff, RM1
Asnaani, A; Gutner, CA; Hofmann, SG; Otto, MW; Smits, JA1
Bachmann, V; Bodenmann, S; Deckert, J; Freitag, C; Hohoff, C; Landolt, HP; Rétey, JV1
Igaz, P; Tulassay, Z1
Kauser, H; Kishore, K; Kumar, S; Panjwani, U; Ray, K; Sahu, S1
Anagnostaras, SG; Sage, JR; Shuman, T; Wood, S1
Fond, G; MacGregor, A; Micoulaud-Franchi, JA1
Costa, G; Driscoll, TR; Isotalo, LK; Liira, J; Ruotsalainen, JH; Sallinen, M; Verbeek, JH1
Baxter, C; Edgar, DM; Gilmour, G; Kellett, DO; Loomis, S; McCarthy, A; Tricklebank, M1
Kauser, H; Kumari, P; Panjwani, U; Ray, K; Sahu, S; Wadhwa, M1
Dance, A1
Han, B; Liu, AJ; Liu, HQ; Song, XR; Tian, JS; Yu, XH; Zhang, LL; Zhang, Y1
Agricola, A; Balló, HE; Frank, B; Franke, AG; Gerdes, C; Gorbulev, S; Gränsmark, P; Lieb, K; Rommel, T; Ruckes, C; Schühle, K; Sebastian, A; Tüscher, O1
Alexandre, C; Ferreira, A; Latremoliere, A; Miracca, G; Scammell, TE; Woolf, CJ; Yamamoto, M1
Mangoni, AA; Rowland, A; Sorich, MJ; van Dyk, M; Warncken, D1
Bernardi, A; Bisagno, V; Cadet, JL; Muñiz, JA; Sosa, M; Torres, OV; Urbano, FJ1
Deka, A; Fogg, LF; Gottlieb, M; Kravitz, HM; Sholtes, D; Westrick, J1
Bovy, L; Dresler, M; Kühn, S; Ohla, K; Repantis, D1
Adam, LC; Dresler, M; Konrad, BN; Kühn, S; Repantis, D1
Dai, C; Lv, J; Peng, Z; Shao, Y; Song, T; Wang, L; Xu, L; Xu, M; Yang, X1
Becker, M; Dresler, M; Kühn, S; Repantis, D1
Ramaekers, JG; Riedel, WJ; Wingelaar, TT; Wingelaar-Jagt, YQ1
Bottenheft, C; Ramaekers, JG; Riedel, WJ; Wingelaar-Jagt, YQ1
Caldwell, JA; Knapik, JJ; Ritland, BM1

Reviews

12 review(s) available for modafinil and caffeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Alertness-enhancing drugs as a countermeasure to fatigue in irregular work hours.
    Chronobiology international, 1997, Volume: 14, Issue:2

    Topics: Amphetamine; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Fatigue; Humans; Modafinil; Pemoline; Sleep Stages; Substance-Related Disorders; Wakefulness; Work Schedule Tolerance

1997
Sleep deprivation.
    Primary care, 2005, Volume: 32, Issue:2

    Topics: Benzhydryl Compounds; Caffeine; Disorders of Excessive Somnolence; Humans; Modafinil; Primary Health Care; Sleep Deprivation; Wakefulness

2005
The use of stimulants to modify performance during sleep loss: a review by the sleep deprivation and Stimulant Task Force of the American Academy of Sleep Medicine.
    Sleep, 2005, Volume: 28, Issue:9

    Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Humans; Methamphetamine; Modafinil; Sleep; Sleep Deprivation; Sleep Initiation and Maintenance Disorders; Time Factors

2005
Shift work sleep disorder: burden of illness and approaches to management.
    Drugs, 2006, Volume: 66, Issue:18

    Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Cost of Illness; Exercise Therapy; Humans; Hypnotics and Sedatives; Melatonin; Modafinil; Phototherapy; Quality of Life; Sleep; Sleep Disorders, Circadian Rhythm; Wakefulness

2006
Interaction profile of armodafinil with medications metabolized by cytochrome P450 enzymes 1A2, 3A4 and 2C19 in healthy subjects.
    Clinical pharmacokinetics, 2008, Volume: 47, Issue:1

    Topics: Administration, Oral; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Clinical Trials as Topic; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Half-Life; Humans; Injections, Intravenous; Male; Metabolic Clearance Rate; Midazolam; Mixed Function Oxygenases; Modafinil; Pharmaceutical Preparations; Theophylline

2008
Fatigue: an overview.
    American family physician, 2008, Nov-15, Volume: 78, Issue:10

    Topics: Behavior Therapy; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Chronic Disease; Fatigue; Female; Humans; Male; Modafinil; Primary Health Care; Sleep; Surveys and Questionnaires

2008
Expert opinion on pharmacotherapy of narcolepsy.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:10

    Topics: Antidepressive Agents, Tricyclic; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Humans; Hypnotics and Sedatives; Immunotherapy; Intracellular Signaling Peptides and Proteins; Modafinil; Narcolepsy; Neuropeptides; Orexins; Selective Serotonin Reuptake Inhibitors; Sodium Oxybate

2010
Cognitive enhancers for anxiety disorders.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 99, Issue:2

    Topics: Animals; Anxiety Disorders; Benzhydryl Compounds; Caffeine; Clinical Trials as Topic; Cognitive Behavioral Therapy; Combined Modality Therapy; Cycloserine; Extinction, Psychological; Humans; Learning; Modafinil; Neurotransmitter Agents; Nootropic Agents; Translational Research, Biomedical; Yohimbine

2011
Psychostimulants and cognition: a continuum of behavioral and cognitive activation.
    Pharmacological reviews, 2014, Volume: 66, Issue:1

    Topics: Animals; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cocaine; Cognition; Humans; Methamphetamine; Methylphenidate; Modafinil

2014
Pharmacological interventions for sleepiness and sleep disturbances caused by shift work.
    The Cochrane database of systematic reviews, 2014, Aug-12, Issue:8

    Topics: Azabicyclo Compounds; Benzhydryl Compounds; Caffeine; Humans; Hypnotics and Sedatives; Melatonin; Modafinil; Piperazines; Randomized Controlled Trials as Topic; Sleep; Sleep Disorders, Circadian Rhythm; Wakefulness; Wakefulness-Promoting Agents

2014
Optimising sleep and performance during night float: A systematic review of evidence and implications for graduate medical education trainees.
    Journal of sleep research, 2021, Volume: 30, Issue:4

    Topics: Adaptation, Physiological; Attention; Caffeine; Education, Medical, Graduate; Energy Drinks; Fatigue; Humans; Melatonin; Modafinil; Reaction Time; Sleep; Sleep Deprivation; Sleep Disorders, Circadian Rhythm; Work Schedule Tolerance

2021

Trials

17 trial(s) available for modafinil and caffeine

ArticleYear
Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine.
    Psychopharmacology, 2002, Volume: 159, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Benzhydryl Compounds; Body Temperature; Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Cognition; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Modafinil; Psychomotor Performance; Reaction Time; Sleep Deprivation; Sleep Stages; Wakefulness

2002
Prior sleep with zolpidem enhances the effect of caffeine or modafinil during 18 hours continuous work.
    Aviation, space, and environmental medicine, 2006, Volume: 77, Issue:5

    Topics: Adult; Aerospace Medicine; Attention; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Delayed-Action Preparations; Double-Blind Method; Electroencephalography; Fatigue; Humans; Hypnotics and Sedatives; Male; Memory; Military Medicine; Modafinil; Pyridines; Reaction Time; Sleep; Wakefulness; Work; Zolpidem

2006
The effects of caffeine, dextroamphetamine, and modafinil on humor appreciation during sleep deprivation.
    Sleep, 2006, Volume: 29, Issue:6

    Topics: Adolescent; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Dextroamphetamine; Disorders of Excessive Somnolence; Female; Humans; Male; Modafinil; Psychological Tests; Psychomotor Agitation; Sleep Deprivation; Wit and Humor as Topic

2006
Cognitive performance during sustained wakefulness: A low dose of caffeine is equally effective as modafinil in alleviating the nocturnal decline.
    Chronobiology international, 2006, Volume: 23, Issue:5

    Topics: Adult; Benzhydryl Compounds; Caffeine; Circadian Rhythm; Cognition; Humans; Male; Modafinil; Time Factors; Wakefulness

2006
The effects of modafinil, caffeine, and dextroamphetamine on judgments of simple versus complex emotional expressions following sleep deprivation.
    The International journal of neuroscience, 2008, Volume: 118, Issue:4

    Topics: Adolescent; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Dextroamphetamine; Discrimination, Psychological; Expressed Emotion; Facial Expression; Female; Humans; Judgment; Male; Modafinil; Sleep Deprivation; Time Factors

2008
Effects of dextroamphetamine, caffeine and modafinil on psychomotor vigilance test performance after 44 h of continuous wakefulness.
    Journal of sleep research, 2008, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Arousal; Attention; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Computers, Handheld; Dextroamphetamine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Modafinil; Polysomnography; Psychomotor Performance; Reaction Time; Sleep; Sleep Deprivation; Wakefulness; Young Adult

2008
Restoration of risk-propensity during sleep deprivation: caffeine, dextroamphetamine, and modafinil.
    Aviation, space, and environmental medicine, 2008, Volume: 79, Issue:9

    Topics: Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Decision Making; Dextroamphetamine; Female; Humans; Intelligence Tests; Judgment; Male; Modafinil; Psychometrics; Risk; Risk-Taking; Sleep Deprivation

2008
Sustaining executive functions during sleep deprivation: A comparison of caffeine, dextroamphetamine, and modafinil.
    Sleep, 2009, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Arousal; Attention; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition Disorders; Decision Making; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Modafinil; Neuropsychological Tests; Pattern Recognition, Visual; Problem Solving; Psychomotor Performance; Sleep Deprivation; Young Adult

2009
Odor identification ability predicts executive function deficits following sleep deprivation.
    The International journal of neuroscience, 2010, Volume: 120, Issue:5

    Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Executive Function; Female; Humans; Male; Modafinil; Odorants; Olfactory Perception; Sleep Deprivation; Time Factors; Young Adult

2010
Polymorphisms of ADORA2A modulate psychomotor vigilance and the effects of caffeine on neurobehavioural performance and sleep EEG after sleep deprivation.
    British journal of pharmacology, 2012, Volume: 165, Issue:6

    Topics: Adult; Aged; Attention; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Electroencephalography; Female; Humans; Male; Middle Aged; Modafinil; Polymorphism, Single Nucleotide; Psychomotor Performance; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A2A; Sleep Deprivation; Wakefulness; Young Adult

2012
Methylphenidate, modafinil, and caffeine for cognitive enhancement in chess: A double-blind, randomised controlled trial.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2017, Volume: 27, Issue:3

    Topics: Adult; Analysis of Variance; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Cross-Sectional Studies; Double-Blind Method; Female; Humans; Male; Methylphenidate; Middle Aged; Modafinil; Neuropsychological Tests; Retrospective Studies; Wakefulness-Promoting Agents

2017
Evaluation of modafinil as a perpetrator of metabolic drug-drug interactions using a model informed cocktail reaction phenotyping trial protocol.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:3

    Topics: Adult; Area Under Curve; Caffeine; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Interactions; Female; Humans; Losartan; Male; Midazolam; Modafinil; Omeprazole; Phenotype; Time Factors; Young Adult

2018
Cognitive enhancement effects of stimulants: a randomized controlled trial testing methylphenidate, modafinil, and caffeine.
    Psychopharmacology, 2021, Volume: 238, Issue:2

    Topics: Adult; Attention; Caffeine; Central Nervous System Stimulants; Cognition; Double-Blind Method; Fatigue; Humans; Male; Methylphenidate; Modafinil; Nootropic Agents; Pilot Projects; Treatment Outcome; Young Adult

2021
Memory enhancement with stimulants: Differential neural effects of methylphenidate, modafinil, and caffeine. A pilot study.
    Brain and cognition, 2021, Volume: 154

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Humans; Magnetic Resonance Imaging; Methylphenidate; Modafinil; Pilot Projects

2021
Modafinil ameliorates the decline in pronunciation-related working memory caused by 36-h acute total sleep deprivation: An ERP study.
    Neurobiology of learning and memory, 2022, Volume: 192

    Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Humans; Male; Memory, Short-Term; Modafinil; Sleep Deprivation

2022
Cognitive enhancement: Effects of methylphenidate, modafinil, and caffeine on latent memory and resting state functional connectivity in healthy adults.
    Human brain mapping, 2022, 10-01, Volume: 43, Issue:14

    Topics: Adult; Brain; Brain Mapping; Caffeine; Central Nervous System Stimulants; Cognition; Double-Blind Method; Humans; Magnetic Resonance Imaging; Male; Methylphenidate; Modafinil; Neural Pathways

2022
Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
    Journal of psychopharmacology (Oxford, England), 2023, Volume: 37, Issue:2

    Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Fatigue; Humans; Modafinil; Psychomotor Performance; Sleep Deprivation; Sleepiness; Wakefulness

2023

Other Studies

26 other study(ies) available for modafinil and caffeine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Dopaminergic role in stimulant-induced wakefulness.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Mar-01, Volume: 21, Issue:5

    Topics: Amphetamine; Animals; Benzhydryl Compounds; Caffeine; Carrier Proteins; Caudate Nucleus; Central Nervous System Stimulants; Disease Models, Animal; Dogs; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Membrane Glycoproteins; Membrane Transport Proteins; Methamphetamine; Mice; Mice, Knockout; Microdialysis; Modafinil; Motor Activity; Narcolepsy; Nerve Tissue Proteins; Orexin Receptors; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Wakefulness

2001
The quest for a smart pill.
    Scientific American, 2003, Volume: 289, Issue:3

    Topics: Alzheimer Disease; Animals; Behavior, Animal; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Cognition Disorders; Humans; Memory; Memory Disorders; Methylphenidate; Modafinil; Technology, Pharmaceutical

2003
Modafinil vs. caffeine: effects on fatigue during sleep deprivation.
    Aviation, space, and environmental medicine, 2004, Volume: 75, Issue:6

    Topics: Adolescent; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Fatigue; Female; Humans; Male; Modafinil; Psychomotor Performance; Sleep Deprivation

2004
Altered sleep latency and arousal regulation in mice lacking norepinephrine.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 78, Issue:4

    Topics: Amphetamine; Animals; Arousal; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Dihydroxyphenylalanine; Electroencephalography; Electromyography; Epinephrine; Female; Male; Mice; Mice, Knockout; Modafinil; Noise; Norepinephrine; Polysomnography; Sleep; Sleep Stages; Sleep, REM; Wakefulness

2004
Psychostimulants and G tolerance in rhesus monkeys: effects of oral modafinil and injected caffeine.
    Aviation, space, and environmental medicine, 2005, Volume: 76, Issue:2

    Topics: Acceleration; Aerospace Medicine; Animals; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Centrifugation; Cerebral Cortex; Electroencephalography; Electrooculography; Fatigue; Hypergravity; Macaca mulatta; Male; Modafinil; Statistics, Nonparametric; Unconsciousness

2005
Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
    Journal of sleep research, 2005, Volume: 14, Issue:3

    Topics: Adult; Arousal; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Dextroamphetamine; Disorders of Excessive Somnolence; Dopamine Agonists; Female; Humans; Male; Modafinil; Neuropsychological Tests; Polysomnography; Psychomotor Performance; Sleep Deprivation; Wakefulness

2005
Ethical use of cogniceuticals in the militaries of democratic nations.
    The American journal of bioethics : AJOB, 2008, Volume: 8, Issue:2

    Topics: Benzhydryl Compounds; Caffeine; Canada; Central Nervous System Stimulants; Cognition; Cross-Cultural Comparison; Democracy; Dextroamphetamine; Drug Prescriptions; Europe; Fatigue; Guidelines as Topic; Humans; Military Medicine; Military Personnel; Modafinil; Psychomotor Performance; Psychotropic Drugs; United States

2008
Sex differences in cognitive estimation during sleep deprivation: effects of stimulant countermeasures.
    The International journal of neuroscience, 2008, Volume: 118, Issue:11

    Topics: Adenosine; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cognition; Cognition Disorders; Dextroamphetamine; Dopamine; Female; Humans; Male; Mental Processes; Modafinil; Neuropsychological Tests; Placebos; Prefrontal Cortex; Sex Characteristics; Sleep Deprivation; Stress, Psychological; Wakefulness; Young Adult

2008
Idiopathic hypersomnia: clinical features and response to treatment.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2009, Dec-15, Volume: 5, Issue:6

    Topics: Actigraphy; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Female; Follow-Up Studies; Humans; Idiopathic Hypersomnia; Male; Methamphetamine; Methylphenidate; Modafinil; Pemoline; Polysomnography; Retrospective Studies; Sodium Oxybate; Treatment Outcome

2009
Effects of paraxanthine and caffeine on sleep, locomotor activity, and body temperature in orexin/ataxin-3 transgenic narcoleptic mice.
    Sleep, 2010, Volume: 33, Issue:7

    Topics: Animals; Ataxin-3; Benzhydryl Compounds; Body Temperature; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Female; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Modafinil; Motor Activity; Narcolepsy; Neuropeptides; Nuclear Proteins; Orexins; Sleep; Theophylline; Transcription Factors

2010
Fatigue and stimulant use in military fighter aircrew during combat operations.
    Aviation, space, and environmental medicine, 2010, Volume: 81, Issue:8

    Topics: Adult; Aerospace Medicine; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Dextroamphetamine; Fatigue; Humans; Hypnotics and Sedatives; Male; Military Personnel; Modafinil; Nicotine; Warfare; Work Schedule Tolerance

2010
Modafinil is not the new caffeine.
    Neurology, 2010, Nov-16, Volume: 75, Issue:20

    Topics: Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Fatigue; Humans; Modafinil; Randomized Controlled Trials as Topic; Sleep Wake Disorders

2010
[Clinical picture and treatment of jet lag].
    Orvosi hetilap, 2011, Dec-11, Volume: 152, Issue:50

    Topics: Benzhydryl Compounds; Biological Clocks; Caffeine; Central Nervous System Depressants; Central Nervous System Stimulants; Circadian Rhythm; Humans; Jet Lag Syndrome; Melatonin; Modafinil; Sleep

2011
Caffeine and modafinil promote adult neuronal cell proliferation during 48 h of total sleep deprivation in rat dentate gyrus.
    Experimental neurology, 2013, Volume: 248

    Topics: Animals; Benzhydryl Compounds; Brain-Derived Neurotrophic Factor; Caffeine; Cell Count; Cell Proliferation; Central Nervous System Stimulants; Corticosterone; Dentate Gyrus; Doublecortin Protein; Male; Modafinil; Neurons; Rats; Rats, Sprague-Dawley; Sleep Deprivation

2013
A preliminary study on cognitive enhancer consumption behaviors and motives of French Medicine and Pharmacology students.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:13

    Topics: Adolescent; Adult; Ascorbic Acid; Benzhydryl Compounds; Caffeine; Education, Medical; Female; France; Humans; Illicit Drugs; Male; Methamphetamine; Methylphenidate; Modafinil; Nootropic Agents; Pharmacology; Piracetam; Prevalence; Students, Health Occupations; Surveys and Questionnaires; Young Adult

2014
Distinct pro-vigilant profile induced in rats by the mGluR5 potentiator LSN2814617.
    Psychopharmacology, 2015, Volume: 232, Issue:21-22

    Topics: Animals; Arousal; Benzhydryl Compounds; Biofeedback, Psychology; Caffeine; Central Nervous System Stimulants; Conditioning, Operant; Dextroamphetamine; Electroencephalography; Excitatory Amino Acid Agonists; Male; Modafinil; Oxadiazoles; Psychomotor Performance; Pyridines; Rats; Rats, Wistar; Reaction Time; Receptor, Metabotropic Glutamate 5; Sleep; Sleep Deprivation; Sleep, REM; Triazoles

2015
Caffeine and modafinil given during 48 h sleep deprivation modulate object recognition memory and synaptic proteins in the hippocampus of the rat.
    Behavioural brain research, 2015, Nov-01, Volume: 294

    Topics: Animals; Benzhydryl Compounds; Caffeine; Disease Models, Animal; Disks Large Homolog 4 Protein; Drug Evaluation, Preclinical; Drug Therapy, Combination; Exploratory Behavior; Hippocampus; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mental Recall; Modafinil; Random Allocation; Rats, Sprague-Dawley; Recognition, Psychology; Sleep Deprivation; Synapses; Synapsins; Synaptophysin; Time Factors; Wakefulness-Promoting Agents

2015
Smart drugs: A dose of intelligence.
    Nature, 2016, Mar-03, Volume: 531, Issue:7592

    Topics: Aging; Amphetamines; Animals; Benzhydryl Compounds; Biomedical Enhancement; Caffeine; Child; Cognition; Dopamine; Healthy Volunteers; Humans; Intelligence; Intelligence Tests; Methylphenidate; Modafinil; Neurotransmitter Agents; Nicotine; Norepinephrine; Off-Label Use; Performance-Enhancing Substances; Prefrontal Cortex; Rats; Substance-Related Disorders; Video Games

2016
The Combination of Scopolamine and Psychostimulants for the Prevention of Severe Motion Sickness.
    CNS neuroscience & therapeutics, 2016, Volume: 22, Issue:8

    Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Cholinergic Antagonists; Dextroamphetamine; Diphenhydramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Granisetron; Locomotion; Male; Mice; Mice, Inbred ICR; Modafinil; Motion Sickness; Rotation; Scopolamine

2016
Decreased alertness due to sleep loss increases pain sensitivity in mice.
    Nature medicine, 2017, Volume: 23, Issue:6

    Topics: Acute Disease; Analgesics; Animals; Behavior, Animal; Benzhydryl Compounds; Caffeine; Chronic Disease; Corticosterone; Electroencephalography; Electromyography; Female; Hyperalgesia; Ibuprofen; Male; Mice; Modafinil; Morphine; Pain; Pain Threshold; Sleep Deprivation; Wakefulness; Wakefulness-Promoting Agents

2017
Acute Regulation of the Arousal-Enhancing Drugs Caffeine and Modafinil on Class IIa HDACs In Vivo and In Vitro: Focus on HDAC7.
    Neurotoxicity research, 2020, Volume: 38, Issue:2

    Topics: Animals; Caffeine; Cell Line; Central Nervous System Stimulants; Corpus Striatum; Histone Deacetylases; Locomotion; Male; Mice; Modafinil; Prefrontal Cortex; RNA, Messenger; Wakefulness-Promoting Agents

2020
Subjective Effects of Modafinil in Military Fighter Pilots During Deployment.
    Aerospace medicine and human performance, 2022, 10-01, Volume: 93, Issue:10

    Topics: Aerospace Medicine; Caffeine; Fatigue; Humans; Military Personnel; Modafinil; Pharmaceutical Preparations; Pilots; Work Schedule Tolerance

2022
Sleep and Injuries in Military Personnel With Suggestions for Improving Sleep and Mitigating Effects of Sleep Loss.
    Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2022, Dec-16, Volume: 22, Issue:4

    Topics: Adult; Caffeine; Humans; Military Personnel; Modafinil; Sleep

2022