moclobemide and toloxatone

moclobemide has been researched along with toloxatone in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's4 (40.00)18.2507
2000's5 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agostinelli, E; Artico, M; Befani, O; Cirilli, R; Costi, R; Di Santo, R; Ferretti, R; Gallinella, B; La Torre, F; Meninno, T; Palmegiani, P; Roux, A; Turini, P1
Alcaro, S; Befani, O; Bolasco, A; Chimenti, F; Chimenti, P; Fioravanti, R; Manna, F; Ortuso, F; Secci, D; Turini, P1
Alcaro, S; Bolasco, A; Cardia, MC; Chimenti, F; Chimenti, P; Fioravanti, R; Manna, F; Ortuso, F; Rossi, F; Secci, D; Turini, P1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Lemoine, P; Mirabaud, C1
Berlin, I; Dingemanse, J; Payan, C; Puech, AJ; Thiede, HM1
Berlin, I; Hergueta, T; Payan, C; Puech, AJ; Robin, L; Thiede, HM; Zimmer, R1
Da Prada, M; Keller, HH; Kettler, R1
Gimbrett, R; Priest, RG; Roberts, M; Steinert, J1

Trials

3 trial(s) available for moclobemide and toloxatone

ArticleYear
A double-blind comparison of moclobemide and toloxatone in out-patients presenting a major depressive disorder.
    Psychopharmacology, 1992, Volume: 106 Suppl

    Topics: Adult; Antidepressive Agents; Benzamides; Depressive Disorder; Double-Blind Method; Humans; Moclobemide; Outpatients; Oxazoles; Oxazolidinones; Psychiatric Status Rating Scales; Psychomotor Performance

1992
Comparative investigation of the effect of moclobemide and toloxatone on monoamine oxidase activity and psychometric performance in healthy subjects.
    Psychopharmacology, 1992, Volume: 106 Suppl

    Topics: Adult; Arousal; Benzamides; Biogenic Monoamines; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Male; Memory; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Psychomotor Performance; Sleep

1992
Comparison of the monoamine oxidase inhibiting properties of two reversible and selective monoamine oxidase-A inhibitors moclobemide and toloxatone, and assessment of their effect on psychometric performance in healthy subjects.
    British journal of clinical pharmacology, 1990, Volume: 30, Issue:6

    Topics: Adult; Benzamides; Double-Blind Method; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Psychometrics; Psychophysiology

1990

Other Studies

7 other study(ies) available for moclobemide and toloxatone

ArticleYear
Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors.
    Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13

    Topics: Drug Design; Kinetics; Models, Molecular; Molecular Structure; Monoamine Oxidase Inhibitors; Oxazolidinones; Piperazines; Piperidines; Pyrrolidines; Structure-Activity Relationship

2005
Monoamine oxidase isoform-dependent tautomeric influence in the recognition of 3,5-diaryl pyrazole inhibitors.
    Journal of medicinal chemistry, 2007, Feb-08, Volume: 50, Issue:3

    Topics: Isoenzymes; Isomerism; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrazoles; Structure-Activity Relationship

2007
Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:10

    Topics: Animals; Cattle; Drug Design; Humans; Models, Molecular; Molecular Conformation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyrazoles; Substrate Specificity

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
[Comparison of the new MAO-A inhibitors moclobemide, brofaromine and toloxatone with tranylcypromine in an animal experiment: significance for clinical practice].
    Psychiatrische Praxis, 1989, Volume: 16 Suppl 1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Benzamides; Blood Pressure; Heart Rate; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Piperidines; Rats; Serotonin; Structure-Activity Relationship; Tranylcypromine

1989
Reversible and selective inhibitors of monoamine oxidase A in mental and other disorders.
    Acta psychiatrica Scandinavica. Supplementum, 1995, Volume: 386

    Topics: Alzheimer Disease; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Benzamides; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Panic Disorder; Phobic Disorders; Piperidines

1995