Compounds > moclobemide

moclobemide and entacapone

moclobemide has been researched along with entacapone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Gordin, A; Illi, A; Ojala-Karlsson, P; Scheinin, M; Sundberg, S1
Illi, A; Koulu, M; Ojala-Karlsson, P; Scheinin, M1

Trials

1 trial(s) available for moclobemide and entacapone

ArticleYear
Simultaneous inhibition of catechol-O-methyltransferase and monoamine oxidase A: effects on hemodynamics and catecholamine metabolism in healthy volunteers.
    Clinical pharmacology and therapeutics, 1996, Volume: 59, Issue:4

    Topics: Administration, Oral; Adult; Analysis of Variance; Antidepressive Agents; Antiparkinson Agents; Benzamides; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Exercise; Hemodynamics; Humans; Male; Moclobemide; Monoamine Oxidase Inhibitors; Nitriles; Parkinson Disease; Reference Values; Rest

1996

Other Studies

5 other study(ies) available for moclobemide and entacapone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Norepinephrine metabolites in plasma as indicators of pharmacological inhibition of monoamine oxidase and catechol O-methyltransferase.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: Antiparkinson Agents; Benzamides; Biomarkers; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Humans; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nitriles; Norepinephrine; Pentanones; Selegiline

1998