mobic has been researched along with titanium-dioxide* in 2 studies
2 other study(ies) available for mobic and titanium-dioxide
| Article | Year |
|---|---|
Nanocrystalline cellulose as a biotemplate for preparation of porous titania thin film as a sorbent for thin film microextraction of ketorolac, meloxicam, diclofenac and mefenamic acid.
The present study included the procedure of preparing porous titania thin film using a direct nanocrystalline cellulose templating (NCC) as a bio-template. The microextraction applicability of the porous film was investigated by thin film microextraction (TFME) of the nonsteroidal anti-inflammatory drugs (NSAIDs) including ketorolac, meloxicam, diclofenac and mefenamic acid from different types of urine sample. The extracted NSAIDs were analyzed by HPLC-UV. Under optimum conditions, the calibration curves were linear within the range of 1.0-500 µg L Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Chromatography, High Pressure Liquid; Diclofenac; Female; Humans; Ketorolac; Limit of Detection; Male; Mefenamic Acid; Meloxicam; Membranes, Artificial; Middle Aged; Nanoparticles; Porosity; Solid Phase Microextraction; Titanium | 2020 |
Optimization of photocatalytic degradation of meloxicam using titanium dioxide nanoparticles: application to pharmaceutical wastewater analysis, treatment, and cleaning validation.
Meloxicam is a commonly prescribed nonsteroidal anti-inflammatory drug with analgesic and fever-reducing effects. In this study, photocatalytic degradation of meloxicam in the presence of TiO2 nanoparticles (TiO2NP) was optimized and applied for pharmaceutical wastewater treatment. A validated stability-indicating orthogonal testing protocol (reversed-phase (RP)-HPLC and capillary zone electrophoresis) was developed and validated for monitoring of meloxicam concentration in the presence of its photodegradation products. Fractional factorial design was employed in order to investigate the effects of pH, irradiation time, UV light intensity, TiO2NP loading, and initial meloxicam concentration on the efficiency of the process. The light intensity was found as the most significant parameter followed by irradiation time and concentration, respectively. The most influencing interactions were noted between irradiation time-concentration and irradiation time-light intensity. The kinetics of meloxicam degradation was investigated at the optimum set of experimental conditions. The protocol was successfully applied for treatment of incurred water samples collected during various cleaning validation cycles. A percentage degradation of 77.34 ± 0.02 % was achieved upon irradiation of samples containing 64.57 ± 0.09 μg/mL with UV light (1012 μW/cm(2), 8 h) in the presence of 0.4 mg/mL TiO2NP at pH 9.0 ± 0.05. Treatment of wastewaters collected during the cleaning validation of each product separately rather than the combined waste should result in a significant improvement in the economics of pharmaceutical wastewater treatment. This could be attributed to the relatively small waste volumes and the ability to tailor the experimental conditions to achieve maximum efficiency. Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Kinetics; Meloxicam; Metal Nanoparticles; Photolysis; Thiazines; Thiazoles; Titanium; Ultraviolet Rays; Wastewater; Water Pollutants, Chemical; Water Purification | 2015 |