ml 236a has been researched along with lovastatin in 5 studies
| Studies (ml 236a) | Trials (ml 236a) | Recent Studies (post-2010) (ml 236a) | Studies (lovastatin) | Trials (lovastatin) | Recent Studies (post-2010) (lovastatin) |
|---|---|---|---|---|---|
| 6 | 0 | 0 | 4,828 | 698 | 873 |
| Protein | Taxonomy | ml 236a (IC50) | lovastatin (IC50) |
|---|---|---|---|
| Chain A, Antigen Cd11a (p180) | Homo sapiens (human) | 2.4 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.0261 | |
| Integrin beta-2 | Homo sapiens (human) | 3.09 | |
| Intercellular adhesion molecule 1 | Homo sapiens (human) | 3.78 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 8.753 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 10 | |
| Neutrophil elastase | Homo sapiens (human) | 0.027 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 0.02 | |
| Integrin alpha-L | Homo sapiens (human) | 3.09 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 8.753 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.02 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0529 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Endo, A; Kuroda, M; Tanzawa, K; Tsujita, Y | 1 |
| Endo, A; Komagata, D; Yamashita, H | 1 |
| Kuwano, H; Nakagawa, K; Serizawa, N; Tanaka, M; Terahara, A; Tsujita, Y | 1 |
| Endo, A; Kuroda, M; Tanzawa, K | 2 |
5 other study(ies) available for ml 236a and lovastatin
| Article | Year |
|---|---|
Inhibition of cholesterol synthesis in vitro and in vivo by ML-236A and ML-236B, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Topics: Acetates; Animals; Binding, Competitive; Caprylates; Cholesterol; Fatty Acids; Gallbladder; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Kidney; Kinetics; Lactones; Liver; Lovastatin; Male; Mevalonic Acid; Mice; Naphthalenes; Naphthols; Organ Specificity; Pyrans; Rats; Sterols | 1977 |
Microbial conversion of compactin (ML-236B) to ML-236A.
Topics: Ascomycota; Hydrolysis; Lovastatin; Naphthalenes; Naphthols; Yeasts | 1986 |
6 alpha-Hydroxy-iso-ML-236B (6 alpha-hydroxy-iso-compactin) and ML-236A, microbial transformation products of ML-236B.
Topics: Biotransformation; Fungi; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Magnetic Resonance Spectroscopy; Mucorales; Naphthalenes; Naphthols; Species Specificity | 1983 |
Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity. 1976.
Topics: Animals; Anticholesteremic Agents; History, 20th Century; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Naphthols; Rats | 2004 |
Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity.
Topics: Animals; Anticholesteremic Agents; Enzyme Activation; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Lovastatin; Microsomes, Liver; Molecular Structure; Naphthols; Penicillium; Rats | 1976 |