ml 23 has been researched along with melatonin in 11 studies
*Melatonin: A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. [MeSH]
*Melatonin: A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant. [MeSH]
| Studies (ml 23) | Trials (ml 23) | Recent Studies (post-2010) (ml 23) | Studies (melatonin) | Trials (melatonin) | Recent Studies (post-2010) (melatonin) |
|---|---|---|---|---|---|
| 13 | 1 | 0 | 23,268 | 1,451 | 9,627 |
| Protein | Taxonomy | ml 23 (IC50) | melatonin (IC50) |
|---|---|---|---|
| Myeloperoxidase | Homo sapiens (human) | 3 | |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | 3.3323 | |
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.0004 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0005 | |
| Melatonin receptor type 1A | Homo sapiens (human) | 0.0025 | |
| Melatonin receptor type 1B | Homo sapiens (human) | 0.0035 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buzzell, GR; McNeill, ME; Menendez-Pelaez, A; Reiter, RJ; Troiani, ME | 1 |
| Kelly, RW; Lincoln, GA | 1 |
| Migliaccio, S; Nordio, M; Reiter, RJ; van Jaarsveld, A; Vaughan, MK; Zisapel, N | 1 |
| Chantegrel, J; Claustrat, B; Luu-Duc, C; Marsura, A; Masson-Pévet, M; Pévet, P | 1 |
| Laudon, M; Yaron, Z; Zisapel, N | 1 |
| Laudon, M; Zisapel, N | 1 |
| Gan, J; Iuvone, PM | 1 |
| Anis, Y; Nir, I; Oaknin-Bendahan, S; Zisapel, N | 1 |
| Robertson, AD; Willis, GL | 2 |
| Willis, GL | 1 |
1 review(s) available for ml 23 and melatonin
| Article | Year |
|---|---|
The role of ML-23 and other melatonin analogues in the treatment and management of Parkinson's disease.
Topics: 5-Methoxytryptamine; Animals; Antiparkinson Agents; Disease Models, Animal; Humans; Levodopa; Melatonin; Parkinson Disease | 2005 |
1 trial(s) available for ml 23 and melatonin
| Article | Year |
|---|---|
Recovery from experimental Parkinson's disease in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride treated marmoset with the melatonin analogue ML-23.
Topics: 5-Methoxytryptamine; Animals; Behavior, Animal; Callithrix; Cross-Over Studies; Eating; Male; Melatonin; Parkinsonian Disorders; Reaction Time; Recovery of Function | 2005 |
9 other study(ies) available for ml 23 and melatonin
| Article | Year |
|---|---|
Effects of short-day photoperiods and of N-(2,4-dinitrophenyl)-5-methoxytryptamine, a putative melatonin antagonist, on melatonin synthesis in the Harderian gland of the Syrian hamster, Mesocricetus auratus.
Topics: 5-Methoxytryptamine; Acetylserotonin O-Methyltransferase; Acetyltransferases; Analysis of Variance; Animals; Cricetinae; Female; Harderian Gland; Lacrimal Apparatus; Lighting; Male; Melatonin; Mesocricetus; Periodicity | 1990 |
Test of ML23 as an antagonist to the effects of melatonin in the ram.
Topics: 5-Methoxytryptamine; Animals; Follicle Stimulating Hormone; Light; Lysine; Male; Melatonin; Reproduction; Serotonin; Testis; Testosterone | 1989 |
A novel melatonin antagonist, N-(2,4-dinitrophenyl)-5-methoxytryptamine neutralizes some effects of melatonin in the female Syrian hamster.
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Estradiol; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Melatonin; Mesocricetus; Organ Size; Ovary; Pituitary Gland; Progesterone; Prolactin; Serotonin; Thyroxine; Triiodothyronine; Uterus | 1989 |
Failure of N-(2,4-dinitrophenyl)-5-methoxytryptamine (a putative melatonin antagonist) and of N-(3,5-dinitrophenyl)-5-methoxytryptamine to prevent the effects of injections of melatonin in the late afternoon on testicular activity of the golden hamster.
Topics: 5-Methoxytryptamine; Animals; Atrophy; Cold Temperature; Cricetinae; Light; Male; Melatonin; Mesocricetus; Serotonin; Testis | 1989 |
N-(2,4-dinitrophenyl)-5-methoxytryptamine, a novel melatonin antagonist: effects on sexual maturation of the male and female rat and on oestrous cycles of the female rat [corrected].
Topics: 5-Methoxytryptamine; Administration, Oral; Animals; Estrus; Female; Male; Melatonin; Ovulation; Rats; Receptors, Melatonin; Receptors, Neurotransmitter; Serotonin; Sexual Maturation; Tryptamines | 1988 |
A novel melatonin antagonist affects melatonin-mediated processes in vitro and in vivo.
Topics: 5-Methoxytryptamine; Animals; Dopamine; Electric Stimulation; Female; Genitalia, Male; Hypothalamus; Male; Melatonin; Rats; Tryptamines | 1987 |
Melatonin receptor-mediated inhibition of cyclic AMP accumulation in chick retinal cell cultures.
Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Iodine Radioisotopes; Melatonin; Neurons; Pertussis Toxin; Photoreceptor Cells; Potassium; Receptors, Cell Surface; Receptors, Melatonin; Retina; Second Messenger Systems; Structure-Activity Relationship; Tryptamines; Virulence Factors, Bordetella | 1994 |
Effects of long-term administration of melatonin and a putative antagonist on the ageing rat.
Topics: 5-Methoxytryptamine; Aging; Animals; Body Weight; Hypothalamus; Iodine Radioisotopes; Male; Medulla Oblongata; Melatonin; Pons; Random Allocation; Rats; Receptors, Cell Surface; Receptors, Melatonin; Survival Rate; Testosterone; Time Factors | 1995 |
Recovery of experimental Parkinson's disease with the melatonin analogues ML-23 and S-20928 in a chronic, bilateral 6-OHDA model: a new mechanism involving antagonism of the melatonin receptor.
Topics: 5-Methoxytryptamine; Animals; Male; Melatonin; Naphthalenes; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, Melatonin; Recovery of Function | 2004 |