mk 912 has been researched along with guanfacine in 3 studies
| Studies (mk 912) | Trials (mk 912) | Recent Studies (post-2010) (mk 912) | Studies (guanfacine) | Trials (guanfacine) | Recent Studies (post-2010) (guanfacine) |
|---|---|---|---|---|---|
| 60 | 3 | 2 | 784 | 180 | 273 |
| Protein | Taxonomy | mk 912 (IC50) | guanfacine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.453 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.134 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.249 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 6.447 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 3.014 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.453 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 2.098 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chhajlani, V; Lien, EJ; Uhlén, S; Wikberg, JE; Xia, Y | 1 |
| Lindblom, J; Tiger, G; Uhlén, S; Wikberg, JE | 1 |
| Arnsten, AF; Franowicz, JS | 1 |
3 other study(ies) available for mk 912 and guanfacine
| Article | Year |
|---|---|
Further evidence for the existence of two forms of alpha 2B-adrenoceptors in rat.
Topics: Adrenergic alpha-Antagonists; Animals; Cell Line; Guanfacine; Kidney; Kinetics; Ligands; Lung; Male; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1993 |
Quantification of alpha2A and alpha2C adrenoceptors in the rat striatum and in different regions of the spinal cord.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Corpus Striatum; Guanfacine; In Vitro Techniques; Kinetics; Male; Quinolizines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord | 1997 |
Actions of alpha-2 noradrenergic agonists on spatial working memory and blood pressure in rhesus monkeys appear to be mediated by the same receptor subtype.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cognition; Dose-Response Relationship, Drug; Drug Interactions; Female; Guanfacine; Hypotension; Idazoxan; Macaca mulatta; Memory; Quinolizines; Receptors, Adrenergic, alpha-2 | 2002 |