Page last updated: 2024-09-04

mk 767 and fenofibrate

mk 767 has been researched along with fenofibrate in 4 studies

Compound Research Comparison

Studies
(mk 767)
Trials
(mk 767)
Recent Studies (post-2010)
(mk 767)
Studies
(fenofibrate)
Trials
(fenofibrate)
Recent Studies (post-2010) (fenofibrate)
320103,0585291,354

Protein Interaction Comparison

ProteinTaxonomymk 767 (IC50)fenofibrate (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)2.371
Adenosine receptor A3Homo sapiens (human)5.701
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.701
5-hydroxytryptamine receptor 2AHomo sapiens (human)2.118
5-hydroxytryptamine receptor 2CHomo sapiens (human)2.371
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.701
Sodium-dependent dopamine transporter Homo sapiens (human)8.633
Peroxisome proliferator-activated receptor alphaHomo sapiens (human)1
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)5.1

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, PJ; Henke, BR; Sternbach, DD; Willson, TM1
Ide, T; Miyachi, H; Murakami, K; Nomura, M; Suzuki, M; Tanase, T; Tsunoda, M; Uchiki, H1
Henke, BR1
Chaput, E; Edgar, AD; Saladin, R; Silvestre, M1

Reviews

2 review(s) available for mk 767 and fenofibrate

ArticleYear
The PPARs: from orphan receptors to drug discovery.
    Journal of medicinal chemistry, 2000, Feb-24, Volume: 43, Issue:4

    Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligands; Models, Molecular; Neoplasms; Nuclear Proteins; Obesity; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2000
Peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes.
    Journal of medicinal chemistry, 2004, Aug-12, Volume: 47, Issue:17

    Topics: Animals; Diabetes Mellitus, Type 2; Humans; Hyperglycemia; Hypoglycemic Agents; Models, Molecular; Molecular Structure; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2004

Other Studies

2 other study(ies) available for mk 767 and fenofibrate

ArticleYear
Design, synthesis, and evaluation of substituted phenylpropanoic acid derivatives as human peroxisome proliferator activated receptor activators. Discovery of potent and human peroxisome proliferator activated receptor alpha subtype-selective activators.
    Journal of medicinal chemistry, 2003, Aug-14, Volume: 46, Issue:17

    Topics: Animals; CHO Cells; Cholesterol; Cricetinae; Fatty Acids, Nonesterified; Humans; Male; Models, Molecular; Phenylpropionates; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Stereoisomerism; Structure-Activity Relationship; Transcription Factors; Transcriptional Activation; Transfection

2003
Fenofibrate and rosiglitazone lower serum triglycerides with opposing effects on body weight.
    Biochemical and biophysical research communications, 2000, May-10, Volume: 271, Issue:2

    Topics: Acyl-CoA Oxidase; Animals; Apolipoprotein A-I; Apolipoprotein C-III; Apolipoproteins C; Body Weight; Carrier Proteins; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fenofibrate; Hypolipidemic Agents; Male; Mice; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Oxidoreductases; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Thiazolidines; Time Factors; Transcription Factors; Triglycerides

2000