mk 436 and nifurtimox
mk 436 has been researched along with nifurtimox in 7 studies
Compound Research Comparison
| Studies (mk 436) | Trials (mk 436) | Recent Studies (post-2010) (mk 436) | Studies (nifurtimox) | Trials (nifurtimox) | Recent Studies (post-2010) (nifurtimox) |
|---|---|---|---|---|---|
| 20 | 0 | 0 | 643 | 28 | 260 |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Jennings, FW | 1 |
| Cunha Neto, E; Rizzo, LV; Silva, R; Teixeira, AR | 1 |
| Cunha Neto, E; Rizzo, LV; Santana, JM; Silva, R; Teixeira, AR | 1 |
| Habbersett, MC; Meurer, RD; Murray, PK | 1 |
| Gutteridge, WE; Hargadon, MR; Hudson, JE; Ross, J | 1 |
| Calixto, MA; Teixeira, AR; Teixeira, ML | 1 |
| Moreno, SN; Yan, W | 1 |
Other Studies
7 other study(ies) available for mk 436 and nifurtimox
| Article | Year |
|---|---|
Chemotherapy of CNS-trypanosomiasis: the combined use of the arsenicals and nitro-compounds.
Topics: Animals; Antiprotozoal Agents; Arsenicals; Brain Diseases; Drug Synergism; Drug Therapy, Combination; Female; Ketoconazole; Metronidazole; Mice; Nifurtimox; Nitro Compounds; Nitroimidazoles; Oxidation-Reduction; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1991 |
Trypanocidal nitroarene treatment of experimental Trypanosoma cruzi infection does not prevent progression of chronic-phase heart lesions in rabbits.
Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Nifurtimox; Nitroimidazoles; Rabbits; Trypanocidal Agents | 1990 |
Malignant, non-Hodgkin's lymphomas in Trypanosoma cruzi-infected rabbits treated with nitroarenes.
Topics: Animals; Chagas Cardiomyopathy; Female; Injections, Intraperitoneal; Lymphoma, Non-Hodgkin; Male; Myocarditis; Myositis; Nifurtimox; Nitrofurans; Nitroimidazoles; Rabbits; Trypanosoma cruzi | 1990 |
Trypanosoma cruzi: efficacy of the 2-substituted, 5-nitroimidazoles, MK-436 and L634,549, in tissue culture and mice.
Topics: Animals; Antiprotozoal Agents; Benzimidazoles; Cell Line; Chagas Disease; Drug Evaluation, Preclinical; Female; Fibroblasts; Humans; Mice; Mice, Inbred BALB C; Muscles; Nifurtimox; Nitroimidazoles; Rats; Trypanosoma cruzi | 1983 |
Crithidia fasciculata: a catalase-containing trypanosomatid sensitive to nitroheterocyclic drugs.
Topics: Animals; Catalase; Crithidia; Nifurtimox; Nitroimidazoles | 1982 |
Chagas' disease: carcinogenic activity of the antitrypanosomal nitroarenes in mice.
Topics: Animals; Carcinogens; Cell Division; Chagas Disease; Female; Liver; Lymph Nodes; Lymphoma; Mice; Molecular Structure; Nifurtimox; Nitroimidazoles; Trypanocidal Agents | 1994 |
A method to assess invasion and intracellular replication of Trypanosoma cruzi based on differential uracil incorporation.
Topics: Animals; Cells, Cultured; DNA Replication; DNA, Protozoan; Drug Evaluation, Preclinical; Drug Resistance; Gamma Rays; Muscle, Skeletal; Nifurtimox; Nitroimidazoles; Rats; Reproduction; Thiadiazoles; Trypanocidal Agents; Trypanosoma cruzi; Uracil | 1998 |