Page last updated: 2024-09-03

mk 287 and web 2086

mk 287 has been researched along with web 2086 in 2 studies

Compound Research Comparison

Studies (mk 287)	Trials (mk 287)	Recent Studies (post-2010) (mk 287)	Studies (web 2086)	Trials (web 2086)	Recent Studies (post-2010) (web 2086)
6	0	0	600	8	31

Protein Interaction Comparison

Protein	Taxonomy	mk 287 (IC50)	web 2086 (IC50)
Platelet-activating factor receptor	Cavia porcellus (domestic guinea pig)		0.1093
Platelet-activating factor receptor	Homo sapiens (human)		0.1735

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bures, MG; Carrera, GM; Davidsen, SK; Guinn, DE; Heyman, HR; May, PD; Phillips, JG; Pireh, D; Sheppard, GS; Steinman, DH	1
Cai, X; Eckman, J; Hussoin, MS; Hwang, SB; Ip, SH; Killian, DB; Libertine-Garahan, L; Qian, C; Scannell, RT; Shen, TY; Yaeger, D; Yeh, CG	1

Other Studies

2 other study(ies) available for mk 287 and web 2086

Article	Year
3-(2-(3-Pyridinyl)thiazolidin-4-oyl)indoles, a novel series of platelet activating factor antagonists. Journal of medicinal chemistry, 1994, Jun-24, Volume: 37, Issue:13 Topics: Administration, Oral; Animals; Capillary Permeability; Edema; In Vitro Techniques; Indoles; Magnetic Resonance Spectroscopy; Male; Mice; Platelet Activating Factor; Rabbits; Rats; Rats, Sprague-Dawley; Serotonin; Skin; Stereoisomerism; Structure-Activity Relationship; Thiazoles	1994
(+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N- hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist. Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11 Topics: Animals; Arachidonic Acid; Blood Platelets; Cell Membrane; CHO Cells; Cricetinae; Drug Evaluation, Preclinical; Edema; Enzyme Inhibitors; Furans; Hematocrit; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urea	1998

Article

Year

3-(2-(3-Pyridinyl)thiazolidin-4-oyl)indoles, a novel series of platelet activating factor antagonists.

Journal of medicinal chemistry, 1994, Jun-24, Volume: 37, Issue:13

Topics: Administration, Oral; Animals; Capillary Permeability; Edema; In Vitro Techniques; Indoles; Magnetic Resonance Spectroscopy; Male; Mice; Platelet Activating Factor; Rabbits; Rats; Rats, Sprague-Dawley; Serotonin; Skin; Stereoisomerism; Structure-Activity Relationship; Thiazoles

1994

(+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N- hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist.

Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

Topics: Animals; Arachidonic Acid; Blood Platelets; Cell Membrane; CHO Cells; Cricetinae; Drug Evaluation, Preclinical; Edema; Enzyme Inhibitors; Furans; Hematocrit; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Urea

1998