Compounds > mk 0663

Page last updated: 2024-09-03

mk 0663 and thalidomide

mk 0663 has been researched along with thalidomide in 5 studies

Compound Research Comparison

Studies (mk 0663)	Trials (mk 0663)	Recent Studies (post-2010) (mk 0663)	Studies (thalidomide)	Trials (thalidomide)	Recent Studies (post-2010) (thalidomide)
549	173	265	9,789	1,385	4,342

Protein Interaction Comparison

Protein	Taxonomy	mk 0663 (IC50)	thalidomide (IC50)
Cereblon isoform 4	Magnetospirillum gryphiswaldense		7.8
Prostaglandin G/H synthase 1	Ovis aries (sheep)		0.37
Prostaglandin G/H synthase 2	Ovis aries (sheep)		0.5
DNA damage-binding protein 1	Homo sapiens (human)		1.38
Protein cereblon	Homo sapiens (human)		1.38

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (80.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Leung, TW; Wong, EH; Wong, KS	1
Almeida, PR; Baltazar, F; Brito, GA; Ferreira, FV; Macedo, FY; Ribeiro, RA; Schmitt, FC; Távora, F	1
Arora, SK; Khanduja, KL; Medhi, B; Pandhi, P; Rao, RS; Saikia, UN; Toor, JS	1
Gnanapandithan, K; Kumar, S; Malhotra, P; Sharma, A; Singh, S; Varma, S	1

Other Studies

5 other study(ies) available for mk 0663 and thalidomide

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Stroke caused by small vessel occlusion in a patient taking etoricoxib and thalidomide. Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2007, Volume: 17, Issue:1 Topics: Adult; Arthritis, Rheumatoid; Cerebral Infarction; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Etoricoxib; Humans; Immunosuppressive Agents; Intracranial Thrombosis; Male; Pyridines; Sulfones; Thalidomide	2007
Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats. Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:1 Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cystitis; Drug Therapy, Combination; Etoricoxib; Hemorrhage; Ifosfamide; Immunoenzyme Techniques; Indomethacin; Male; Mesna; Pentoxifylline; Protective Agents; Pyridines; Rats; Rats, Wistar; Sulfones; Thalidomide	2008
Experimentally induced various inflammatory models and seizure: understanding the role of cytokine in rat. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2008, Volume: 18, Issue:10 Topics: Acetic Acid; Analysis of Variance; Animals; Arthritis; Colitis; Cyclooxygenase Inhibitors; Cytokines; Disease Models, Animal; DNA Fragmentation; Etoricoxib; Freund's Adjuvant; Immunosuppressive Agents; Inflammation; Male; Pyridines; Rats; Rats, Wistar; Seizures; Sulfones; Thalidomide	2008
Development of multiple myeloma in a case of longstanding ankylosing spondylitis: more than a coincidence? International journal of rheumatic diseases, 2011, Volume: 14, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Diphosphonates; Etoricoxib; Humans; Imidazoles; Male; Middle Aged; Multiple Myeloma; Pyridines; Sacroiliitis; Spondylitis, Ankylosing; Sulfones; Thalidomide; Zoledronic Acid	2011