mk 0663 has been researched along with raltitrexed in 1 studies
| Studies (mk 0663) | Trials (mk 0663) | Recent Studies (post-2010) (mk 0663) | Studies (raltitrexed) | Trials (raltitrexed) | Recent Studies (post-2010) (raltitrexed) |
|---|---|---|---|---|---|
| 549 | 173 | 265 | 580 | 143 | 121 |
| Protein | Taxonomy | mk 0663 (IC50) | raltitrexed (IC50) |
|---|---|---|---|
| Thymidylate synthase | Escherichia coli | 7.0667 | |
| Dihydrofolate reductase | Homo sapiens (human) | 1.8578 | |
| Thymidylate synthase | Lacticaseibacillus casei | 8.2667 | |
| Thymidylate synthase | Homo sapiens (human) | 1.208 | |
| Thymidylate synthase | Mus musculus (house mouse) | 0.67 | |
| Thymidylate synthase | Escherichia coli K-12 | 2.32 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 2.32 | |
| Folate receptor beta | Homo sapiens (human) | 0.384 | |
| Folate receptor alpha | Homo sapiens (human) | 0.015 | |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | 0.26 | |
| Reduced folate transporter | Homo sapiens (human) | 0.0063 | |
| Thymidylate synthase | Rattus norvegicus (Norway rat) | 0.9 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 1.7956 | |
| Proton-coupled folate transporter | Homo sapiens (human) | 0.0995 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
1 other study(ies) available for mk 0663 and raltitrexed
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |