mk 0663 has been researched along with prednisolone in 7 studies
| Studies (mk 0663) | Trials (mk 0663) | Recent Studies (post-2010) (mk 0663) | Studies (prednisolone) | Trials (prednisolone) | Recent Studies (post-2010) (prednisolone) |
|---|---|---|---|---|---|
| 549 | 173 | 265 | 34,414 | 3,302 | 7,141 |
| Protein | Taxonomy | mk 0663 (IC50) | prednisolone (IC50) |
|---|---|---|---|
| Glucocorticoid receptor | Homo sapiens (human) | 0.0278 | |
| Progesterone receptor | Homo sapiens (human) | 2.08 | |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | 0.0565 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.016 | |
| Mineralocorticoid receptor | Homo sapiens (human) | 0.0322 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.016 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.016 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.016 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Berens, N; Bröcker, EB; Seitz, CS; Trautmann, A | 1 |
| Leibur, E; Tamme, T; Tiigimae-Saar, J | 1 |
| Guan, M; Liu, S; Xu, L; Xue, Y | 1 |
| Feist, J; Murray, A; Schulze-Koops, H; Skapenko, A | 1 |
1 review(s) available for mk 0663 and prednisolone
| Article | Year |
|---|---|
Leg ulceration in rheumatoid arthritis--an underreported multicausal complication with considerable morbidity: analysis of thirty-six patients and review of the literature.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Rheumatoid; Etoricoxib; Female; Gram-Positive Bacterial Infections; Humans; Isoxazoles; Leflunomide; Leg; Leg Ulcer; Male; Methotrexate; Middle Aged; Prednisolone; Pseudomonas aeruginosa; Pseudomonas Infections; Pyridines; Retrospective Studies; Risk Factors; Sulfones | 2010 |
2 trial(s) available for mk 0663 and prednisolone
| Article | Year |
|---|---|
The effect of prednisolone on reduction of complaints after impacted third molar removal.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Drug Combinations; Edema; Etoricoxib; Female; Glucocorticoids; Humans; Male; Middle Aged; Molar, Third; Pain Measurement; Pain, Postoperative; Postoperative Complications; Prednisolone; Premedication; Prospective Studies; Pyridines; Range of Motion, Articular; Sulfones; Tooth Extraction; Tooth, Impacted; Trismus; Young Adult | 2010 |
Comparison of Prednisolone, Etoricoxib, and Indomethacin in Treatment of Acute Gouty Arthritis: An Open-Label, Randomized, Controlled Trial.
Topics: Adult; Arthritis, Gouty; Etoricoxib; Female; Humans; Indomethacin; Male; Pain Measurement; Prednisolone; Pyridines; Recurrence; Sulfones; Treatment Outcome | 2016 |
4 other study(ies) available for mk 0663 and prednisolone
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
A Rare Side Effect of Checkpoint Inhibitor Therapy-Nivolumab-Induced Axial Polyarthritis of the Facet and Costovertebral Joints.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Immunological; Etoricoxib; Glucocorticoids; Humans; Magnetic Resonance Imaging; Male; Melanoma; Middle Aged; Nivolumab; Prednisolone; Range of Motion, Articular; Ribs; Skin Neoplasms; Spondylarthritis; Sternocostal Joints; Treatment Outcome; Zygapophyseal Joint | 2019 |