mk 0663 has been researched along with nimesulide in 10 studies
| Studies (mk 0663) | Trials (mk 0663) | Recent Studies (post-2010) (mk 0663) | Studies (nimesulide) | Trials (nimesulide) | Recent Studies (post-2010) (nimesulide) |
|---|---|---|---|---|---|
| 549 | 173 | 265 | 1,272 | 200 | 271 |
| Protein | Taxonomy | mk 0663 (IC50) | nimesulide (IC50) |
|---|---|---|---|
| Myeloperoxidase | Homo sapiens (human) | 2.1 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 6.2 | |
| Procathepsin L | Homo sapiens (human) | 1.92 | |
| Leukotriene A-4 hydrolase | Homo sapiens (human) | 0.023 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 2.493 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 1.8947 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 1.16 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Benoit, V; de Leval, X; Dogné, JM; Frederich, M; Julémont, F; Pirotte, B | 1 |
| Meena, S; Nageswara Rao, R; Raghuram Rao, A | 1 |
| Mullangi, R; Pavan Kumar, VV; Ramani, AV; Srinivas, NR; Vinu, MC | 1 |
| Asero, R | 1 |
| Bhushan, A; Kaur, P; Mir, R; Sharma, S; Singh, N; Singh, TP; Sinha, M; Srinivasan, A; Vikram, G | 1 |
| Aujla, U; Bjarnason, I; Kvasnovsky, CL | 1 |
| Davydkin, IL; Zolotovskaya, IA | 1 |
| Davydkin, IL; Zolotovskaia, IA | 1 |
| Alvarenga-Brant, R; Costa, FO; Cota, LOM; Esteves-Lima, RP; Mattos-Pereira, GH | 1 |
3 review(s) available for mk 0663 and nimesulide
| Article | Year |
|---|---|
First and second generations of COX-2 selective inhibitors.
Topics: Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etoricoxib; Gastrointestinal Diseases; Humans; Isoenzymes; Isoxazoles; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyridines; Sulfonamides; Sulfones | 2004 |
An overview of the recent developments in analytical methodologies for determination of COX-2 inhibitors in bulk drugs, pharmaceuticals and biological matrices.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Industry; Etodolac; Etoricoxib; Lactones; Models, Chemical; Pyrazoles; Pyridines; Spectrophotometry; Sulfonamides; Sulfones; Ultraviolet Rays | 2005 |
Nonsteroidal anti-inflammatory drugs and exacerbations of inflammatory bowel disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Etoricoxib; Gastrointestinal Tract; Humans; Inflammatory Bowel Diseases; Observational Studies as Topic; Pain; Pyrazoles; Pyridines; Recurrence; Sulfonamides; Sulfones | 2015 |
3 trial(s) available for mk 0663 and nimesulide
| Article | Year |
|---|---|
Etoricoxib challenge in patients with chronic urticaria with NSAID intolerance.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Eruptions; Etoricoxib; Female; Humans; Male; Middle Aged; Pyridines; Single-Blind Method; Sulfonamides; Sulfones; Tramadol; Urticaria | 2007 |
[Effect of nonsteroidal anti-inflammatory drugs on the indicators of cardiovascular risk in patients with acute nonspecific back pain].
Topics: Acute Pain; Aged; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Humans; Male; Meloxicam; Middle Aged; Pyridines; Sulfonamides; Sulfones; Thiazines; Thiazoles; Treatment Outcome | 2015 |
Preemptive effects of etoricoxib, acetaminophen, nimesulide, and ibuprofen on postoperative pain management after single-implant surgery: A randomized clinical trial.
Topics: Acetaminophen; Dental Implants; Double-Blind Method; Etoricoxib; Female; Humans; Ibuprofen; Male; Middle Aged; Pain, Postoperative | 2023 |
4 other study(ies) available for mk 0663 and nimesulide
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Simultaneous quantitation of etoricoxib, salicylic acid, valdecoxib, ketoprofen, nimesulide and celecoxib in plasma by high-performance liquid chromatography with UV detection.
Topics: Animals; Celecoxib; Chromatography, High Pressure Liquid; Etoricoxib; Humans; Isoxazoles; Ketoprofen; Male; Pyrazoles; Pyridines; Rats; Rats, Wistar; Reproducibility of Results; Salicylic Acid; Spectrophotometry, Ultraviolet; Sulfonamides; Sulfones | 2006 |
Structural and binding studies of C-terminal half (C-lobe) of lactoferrin protein with COX-2-specific non-steroidal anti-inflammatory drugs (NSAIDs).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cattle; Crystallography, X-Ray; Cyclooxygenase 2 Inhibitors; Etoricoxib; In Vitro Techniques; Isoxazoles; Lactoferrin; Models, Molecular; Peptide Fragments; Protein Binding; Protein Conformation; Pyridines; Sulfonamides; Sulfones | 2010 |
[Cognitive-cytokine effect of nonsteroidal antiinflammatory drugs in the therapy of elderly patients with osteoarthritis].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cognition; Cognition Disorders; Cytokines; Etoricoxib; Female; Humans; Interleukin-1beta; Interleukin-6; Male; Meloxicam; Osteoarthritis; Prospective Studies; Pyridines; Sulfonamides; Sulfones; Thiazines; Thiazoles; Transforming Growth Factor beta1 | 2017 |