Page last updated: 2024-09-03

mk 0663 and medroxyprogesterone acetate

mk 0663 has been researched along with medroxyprogesterone acetate in 2 studies

Compound Research Comparison

Studies
(mk 0663)
Trials
(mk 0663)
Recent Studies (post-2010)
(mk 0663)
Studies
(medroxyprogesterone acetate)
Trials
(medroxyprogesterone acetate)
Recent Studies (post-2010) (medroxyprogesterone acetate)
5491732655,1231,1151,099

Protein Interaction Comparison

ProteinTaxonomymk 0663 (IC50)medroxyprogesterone acetate (IC50)
Estrogen receptorHomo sapiens (human)0.924
Glucocorticoid receptorHomo sapiens (human)0.013
Progesterone receptorHomo sapiens (human)2.5081
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.019
Mineralocorticoid receptor Homo sapiens (human)1.197
Androgen receptorHomo sapiens (human)0.0061
Androgen receptorRattus norvegicus (Norway rat)0.279
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.019
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.019
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.019
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.197
Aldo-keto reductase family 1 member C3Homo sapiens (human)1.4059
Aldo-keto reductase family 1 member C2 Homo sapiens (human)4.0405
Aldo-keto reductase family 1 member C1Homo sapiens (human)1.8
Estrogen receptor betaHomo sapiens (human)0.924

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Agnes, JP; Báfica, A; Bishop, AJR; Bruxel, MA; Casagrande, T; Cassali, GD; das Neves, RN; Delgobo, M; Falchetti, M; Garcia, APV; Gelain, DP; Gonçalves, RM; Mendes, DAGB; Moreira, JCF; Rafacho, A; Somensi, N; Vieira, TC; Zanotto-Filho, A1

Other Studies

2 other study(ies) available for mk 0663 and medroxyprogesterone acetate

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice.
    Cancer letters, 2021, 04-01, Volume: 502

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aromatase; Breast Neoplasms; Cell Line, Tumor; Chemokine CCL2; Cyclooxygenase 2; Diet, High-Fat; Dinoprostone; Disease Models, Animal; Etoricoxib; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; MCF-7 Cells; Medroxyprogesterone Acetate; Mice; Sugars; Up-Regulation

2021