mk 0663 has been researched along with ethinyl estradiol in 3 studies
| Studies (mk 0663) | Trials (mk 0663) | Recent Studies (post-2010) (mk 0663) | Studies (ethinyl estradiol) | Trials (ethinyl estradiol) | Recent Studies (post-2010) (ethinyl estradiol) |
|---|---|---|---|---|---|
| 549 | 173 | 265 | 9,070 | 1,566 | 1,732 |
| Protein | Taxonomy | mk 0663 (IC50) | ethinyl estradiol (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 2 | Homo sapiens (human) | 2.2 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Estrogen receptor | Homo sapiens (human) | 0.0035 | |
| Glucocorticoid receptor | Homo sapiens (human) | 1.71 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 1.71 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.959 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 5.678 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 4.8812 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 1.71 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 1.71 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.959 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 1.71 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.054 | |
| Sulfotransferase 1A1 | Homo sapiens (human) | 0.02 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.559 | |
| Aldehyde oxidase | Homo sapiens (human) | 0.57 | |
| Nuclear receptor subfamily 1 group I member 3 | Homo sapiens (human) | 3 | |
| Estrogen receptor beta | Homo sapiens (human) | 0.0129 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Agrawal, N; Crumley, T; Gottesdiener, K; Hunt, T; Larson, P; Mehta, A; Schwartz, J; Smith, WB; Wong, P | 1 |
1 trial(s) available for mk 0663 and ethinyl estradiol
| Article | Year |
|---|---|
The effect of etoricoxib on the pharmacokinetics of oral contraceptives in healthy participants.
Topics: Adolescent; Adult; Contraceptives, Oral, Combined; Cyclooxygenase Inhibitors; Drug Combinations; Drug Interactions; Etoricoxib; Female; Headache; Humans; Mestranol; Middle Aged; Nausea; Norethindrone; Pyridines; Serum Albumin; Sex Hormone-Binding Globulin; Sulfones | 2009 |
2 other study(ies) available for mk 0663 and ethinyl estradiol
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |