mk 0663 has been researched along with diphenhydramine in 2 studies
| Studies (mk 0663) | Trials (mk 0663) | Recent Studies (post-2010) (mk 0663) | Studies (diphenhydramine) | Trials (diphenhydramine) | Recent Studies (post-2010) (diphenhydramine) |
|---|---|---|---|---|---|
| 549 | 173 | 265 | 4,146 | 415 | 542 |
| Protein | Taxonomy | mk 0663 (IC50) | diphenhydramine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.98 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 3.542 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 1.05 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.372 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.162 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.346 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.647 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 3.542 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 1.295 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.98 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.171 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 1.118 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 3.8852 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
2 other study(ies) available for mk 0663 and diphenhydramine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |