Page last updated: 2024-09-03

mk 0663 and dexfenfluramine

mk 0663 has been researched along with dexfenfluramine in 2 studies

Compound Research Comparison

Studies (mk 0663)	Trials (mk 0663)	Recent Studies (post-2010) (mk 0663)	Studies (dexfenfluramine)	Trials (dexfenfluramine)	Recent Studies (post-2010) (dexfenfluramine)
549	173	265	226	17	20

Protein Interaction Comparison

Protein	Taxonomy	dexfenfluramine (IC50)
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	3.403
5-hydroxytryptamine receptor 1B	Rattus norvegicus (Norway rat)	3.403
Sigma non-opioid intracellular receptor 1	Homo sapiens (human)	0.516

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Avorn, J	1

Other Studies

2 other study(ies) available for mk 0663 and dexfenfluramine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Keeping science on top in drug evaluation. The New England journal of medicine, 2007, Aug-16, Volume: 357, Issue:7 Topics: Advisory Committees; Cardiovascular Diseases; Conflict of Interest; Cyclooxygenase Inhibitors; Dexfenfluramine; Drug Approval; Drug Evaluation; Drug Industry; Etoricoxib; Humans; Hypoglycemic Agents; Lactones; Pyridines; Risk; Rosiglitazone; Sulfones; Thiazolidinediones; United States; United States Food and Drug Administration	2007

Article

Year

Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.

Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008

Keeping science on top in drug evaluation.

The New England journal of medicine, 2007, Aug-16, Volume: 357, Issue:7

Topics: Advisory Committees; Cardiovascular Diseases; Conflict of Interest; Cyclooxygenase Inhibitors; Dexfenfluramine; Drug Approval; Drug Evaluation; Drug Industry; Etoricoxib; Humans; Hypoglycemic Agents; Lactones; Pyridines; Risk; Rosiglitazone; Sulfones; Thiazolidinediones; United States; United States Food and Drug Administration

2007