Compounds > mk 0663
Page last updated: 2024-09-03

mk 0663 and desloratadine

mk 0663 has been researched along with desloratadine in 1 studies

Compound Research Comparison

Studies
(mk 0663)		Trials
(mk 0663)		Recent Studies (post-2010)
(mk 0663)		Studies
(desloratadine)		Trials
(desloratadine)		Recent Studies (post-2010) (desloratadine)
549173265465146166

Protein Interaction Comparison

ProteinTaxonomymk 0663 (IC50)desloratadine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.03
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.116
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.107
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.339
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.292
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.267
Alpha-2B adrenergic receptorHomo sapiens (human)2.146
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.446
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.116
Histamine H2 receptorHomo sapiens (human)1.099
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.033
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.03
Sodium-dependent serotonin transporterHomo sapiens (human)0.23
Histamine H1 receptorHomo sapiens (human)0.0059
D(3) dopamine receptorHomo sapiens (human)1.906
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.043
5-hydroxytryptamine receptor 6Homo sapiens (human)2.171
Sodium-dependent dopamine transporter Homo sapiens (human)3.879

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1

Other Studies

1 other study(ies) available for mk 0663 and desloratadine

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013